Review: could Meropenem cause Thrombocytopenia?


Summary

Thrombocytopenia is found among people who take Meropenem, especially for people who are male, 60+ old , have been taking the drug for < 1 month, also take medication Vancomycin, and have Prophylaxis . We study 5,559 people who have side effects while taking Meropenem from FDA and social media. Among them, 465 have Thrombocytopenia. Find out below who they are, when they have Thrombocytopenia and more.

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Meropenem

Meropenem has active ingredients of meropenem. It is often used in pneumonia. (latest outcomes from Meropenem 7,733 users)

Thrombocytopenia

Thrombocytopenia (decrease of platelets in blood) has been reported by people with breathing difficulty, death, drug ineffective, sepsis, diarrhea (latest reports from 132,179 Thrombocytopenia patients).

On Sep, 18, 2016

5,559 people reported to have side effects when taking Meropenem.
Among them, 465 people (8.36%) have Thrombocytopenia


Number of reports submitted per year:

Could Meropenem cause Thrombocytopenia?

Time on Meropenem when people have Thrombocytopenia *:

  • < 1 month: 93.78 %
  • 1 - 6 months: 5.81 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.41 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Thrombocytopenia when taking Meropenem *:

  • female: 45.52 %
  • male: 54.48 %

Age of people who have Thrombocytopenia when taking Meropenem *:

  • 0-1: 1.2 %
  • 2-9: 2.89 %
  • 10-19: 4.1 %
  • 20-29: 6.51 %
  • 30-39: 3.61 %
  • 40-49: 11.81 %
  • 50-59: 13.49 %
  • 60+: 56.39 %

Top conditions involved for these people *:

  • Prophylaxis (70 people, 15.05%)
  • Pneumonia (38 people, 8.17%)
  • Myelodysplastic Syndrome (30 people, 6.45%)
  • Acute Lymphocytic Leukaemia (29 people, 6.24%)
  • Multiple Myeloma (27 people, 5.81%)

Top co-used drugs for these people *:

  • Vancomycin (104 people, 22.37%)
  • Fluconazole (67 people, 14.41%)
  • Lasix (60 people, 12.90%)
  • Allopurinol (58 people, 12.47%)
  • Acyclovir (53 people, 11.40%)

Top other side effects for these people *:

  • Anaemia (112 people, 24.09%)
  • Pyrexia (91 people, 19.57%)
  • White Blood Cell Count Decreased (85 people, 18.28%)
  • Neutrophil Count Decreased (64 people, 13.76%)
  • Neutropenia (63 people, 13.55%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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