Review: could Metformin Hydrochloride cause Muscle Atrophy?


Summary

Muscle atrophy is found among people who take Metformin Hydrochloride, especially for people who are male, 60+ old , have been taking the drug for 6 - 12 months, also take medication Simvastatin, and have Hypercholesterolaemia . We study 12,307 people who have side effects while taking Metformin hydrochloride from FDA and social media. Among them, 11 have Muscle atrophy. Find out below who they are, when they have Muscle atrophy and more.

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Metformin Hydrochloride

Metformin hydrochloride has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin hydrochloride 17,825 users)

Muscle Atrophy

Muscle atrophy (a decrease in the mass of the muscle) has been reported by people with weight decreased, nephrogenic systemic fibrosis, pain, gait disturbance, weakness (latest reports from 7,949 Muscle atrophy patients).

On Sep, 18, 2016

12,307 people reported to have side effects when taking Metformin Hydrochloride.
Among them, 11 people (0.09%) have Muscle Atrophy


Number of reports submitted per year:

Could Metformin hydrochloride cause Muscle atrophy?

Time on Metformin Hydrochloride when people have Muscle Atrophy *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 50 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 50 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Muscle Atrophy when taking Metformin Hydrochloride *:

  • female: 9.09 %
  • male: 90.91 %

Age of people who have Muscle Atrophy when taking Metformin Hydrochloride *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 9.09 %
  • 60+: 90.91 %

Severity if Muscle Atrophy when taking Metformin Hydrochloride **:

  • least: 0.0 %
  • moderate: 100 %
  • severe: 0.0 %
  • most severe: 0.0 %

Top conditions involved for these people *:

  • Hypercholesterolaemia (3 people, 27.27%)
  • Type 2 Diabetes Mellitus (2 people, 18.18%)
  • Myocardial Infarction (2 people, 18.18%)
  • Asthma (2 people, 18.18%)
  • Anxiety (2 people, 18.18%)

Top co-used drugs for these people *:

  • Simvastatin (4 people, 36.36%)
  • Ramipril (3 people, 27.27%)
  • Aspirin (2 people, 18.18%)
  • Tafil (1 person, 9.09%)
  • Gabapentin (1 person, 9.09%)

Top other side effects for these people *:

  • Pain (4 people, 36.36%)
  • Myopathy (4 people, 36.36%)
  • Muscular Weakness (4 people, 36.36%)
  • Blood Creatine Phosphokinase Increased (4 people, 36.36%)
  • Weight Decreased (3 people, 27.27%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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