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Review: could Metformin hydrochloride cause Bone and joint pain (Joint pain)?

Summary: Bone and joint pain is found among people who take Metformin hydrochloride, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Aspirin, and have Diabetes.

We study 12,771 people who have side effects while taking Metformin hydrochloride from FDA and social media. Among them, 274 have Bone and joint pain. Find out below who they are, when they have Bone and joint pain and more.

You are not alone: join a mobile support group for people who take Metformin hydrochloride and have Bone and joint pain >>>

 

 

 

 

Metformin hydrochloride

Metformin hydrochloride has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from 14,611 Metformin hydrochloride users)

Bone and joint pain

Bone and joint pain has been reported by people with rheumatoid arthritis, osteoporosis, high blood cholesterol, high blood pressure, multiple sclerosis. (latest reports from 118,740 Bone and joint pain patients)

On Feb, 1, 2015: 12,771 people reported to have side effects when taking Metformin hydrochloride. Among them, 274 people (2.15%) have Bone And Joint Pain.

Trend of Bone and joint pain in Metformin hydrochloride reports

Time on Metformin hydrochloride when people have Bone and joint pain * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Bone and joint pain9.68%35.48%3.23%0.00%29.03%22.58%0.00%

Gender of people who have Bone and joint pain when taking Metformin hydrochloride * :

FemaleMale
Bone and joint pain61.54%38.46%

Age of people who have Bone and joint pain when taking Metformin hydrochloride * :

0-12-910-1920-2930-3940-4950-5960+
Bone and joint pain0.00%0.00%0.90%1.35%5.86%13.96%31.98%45.95%

Severity of Bone and joint pain when taking Metformin hydrochloride ** :

leastmoderateseveremost severe
Bone and joint pain0.00%61.90%38.10%0.00%

How people recovered from Bone and joint pain ** :

while on the drugafter off the drugnot yet
Bone and joint pain0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Diabetes mellitus (52 people, 18.98%)
  2. Hypertension (36 people, 13.14%)
  3. Rheumatoid arthritis (28 people, 10.22%)
  4. Type 2 diabetes mellitus (20 people, 7.30%)
  5. Multiple myeloma (17 people, 6.20%)

Top co-used drugs for these people * :

  1. Aspirin (53 people, 19.34%)
  2. Lisinopril (37 people, 13.50%)
  3. Simvastatin (30 people, 10.95%)
  4. Actos (27 people, 9.85%)
  5. Lantus (26 people, 9.49%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Bone And Joint Pain while taking Metformin Hydrochloride?

You are not alone! Join a mobile support group:
- support group for people who take Metformin hydrochloride and have Bone And Joint Pain
- support group for people who take Metformin hydrochloride
- support group for people who have Bone And Joint Pain

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Comments from related studies:

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    Sumac on Oct, 24, 2014:

    I think a lot of you have disseminated histoplasmosis. Histoplasmosis is carried by bats.

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  • From this study (6 months ago):

  • I've been diagnosed with sero-negative rheumatoid arthritis. I have only tested minimally positive on the anti-CCP test and had a slightly high SED rate. My most recent tests showed some slight elevation in some RA marker tests, but nothing really significant. My rheumatologist is now doubting whether I have RA or some other pain syndrome going on.

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    IHateRA on Jul, 22, 2014:

    My first RA Dr. put me on Plaquenil, it seemed to work for six months, then stopped - I thought the dose would be adjusted but it wasn't, so I went to another RA Doc - C-RP wasn't too high, sero neg. Was put on methotrexate - I ended up with a mouth sore the NEXT day, then bumps started appearing on my face, like zits, but NOT zits. I didn't touch them, but they ulcerated, left me full of scars on face, legs, etc - I have been OFF methotrexate for 5 years AND still have the same problem along with a daily fever (100+) and severe sweating - I knew the bumps were a sign of being allergic to Methotrexate, I quit it right away, called Dr. to get in - they told me 3 months (I was an established patient). In terms of fever and sweating, the ONLY thing I have in common with some of these posts and drug lists is METHOTREXATE - I wouldn't allow a pet to take it. I seem to have more in common with a friend who as MS - but my reg. doc doesn't listen to that. I can't take bio. drugs (live in "fungal" region), so I take pain medicine - as little as possible, I guess the Methotrexate is STILL messing with my body. I have a very good acupuncturist - when I told him that my Doc. wasn't "sure" about RA, he poked me (lightly) with his finger in two places and ask which hurt more. He confirmed the RA as it travels on certain meridians in Chinese medicine. Had I picked a different spot for hurting more, then we would have to figure out what I really had. My joints are deteriorating but now I'm afraid of the drugs for RA, so I just put up with and manage the pain (which is extreme) with pain meds, cold therapy (I love my cryo-cuff), and acupuncture. I wish that the side effects of RA drugs weren't as bad as they are! Leaving Cymbalta, Lyrica, Plaquenil and Methotrexate (all at different times) OUT of my body made me realize that they did affect me - I was "foggy" and sluggish mentally but didn't really notice it until I quit them.

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