Home > Metformin hydrochloride > Kidney stones > Metformin hydrochloride and Kidney stones
Review: could Metformin hydrochloride cause Kidney stones?
Summary: Kidney stones is found among people who take Metformin hydrochloride, especially for people who are female, 50-59 old, also take medication Aspirin, and have Diabetes mellitus.
We study 12,759 people who have side effects while taking Metformin hydrochloride from FDA and social media. Among them, 76 have Kidney stones. Find out below who they are, when they have Kidney stones and more.
You are not alone: join a mobile support group for people who take Metformin hydrochloride and have Kidney stones >>>
Metformin hydrochloride (latest outcomes from 14,601 users) has active ingredients of metformin hydrochloride. It is often used in diabetes.
Kidney stones (latest reports from 14,040 patients) has been reported by people with multiple sclerosis, osteoporosis, high blood pressure, rheumatoid arthritis, pain.
On Nov, 25, 2014: 12,759 people reported to have side effects when taking Metformin hydrochloride. Among them, 76 people (0.60%) have Kidney Stones.
Time on Metformin hydrochloride when people have Kidney stones * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Kidney stones||0.00%||12.50%||0.00%||0.00%||25.00%||12.50%||50.00% |
Gender of people who have Kidney stones when taking Metformin hydrochloride * :
|Kidney stones||51.85%||48.15% |
Age of people who have Kidney stones when taking Metformin hydrochloride * :
|Kidney stones||0.00%||0.00%||0.00%||0.00%||5.66%||22.64%||39.62%||32.08% |
Severity of Kidney stones when taking Metformin hydrochloride ** :
|least||moderate||severe||most severe |
|Kidney stones||0.00%||0.00%||100.00%||0.00% |
How people recovered from Kidney stones ** :
|while on the drug||after off the drug||not yet |
|Kidney stones||0.00%||0.00%||100.00% |
Top conditions involved for these people * :
- Diabetes mellitus (17 people, 22.37%)
- Metastatic neoplasm (13 people, 17.11%)
- Type 2 diabetes mellitus (12 people, 15.79%)
- Breast cancer metastatic (11 people, 14.47%)
- Hypersensitivity (10 people, 13.16%)
Top co-used drugs for these people * :
- Aspirin (27 people, 35.53%)
- Zometa (23 people, 30.26%)
- Crestor (19 people, 25.00%)
- Colace (19 people, 25.00%)
- Insulin (18 people, 23.68%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
Comments for this study:
Jones60 (6 months ago):
I have my first ever stone after a 6 month stint on Metformin....Now Im wondering if I should stop taking this drug
Reply the comment
Wil (2 years ago):
UPDATE: August and September 2012 had Lithotripsy for two large stones. Also stopped Metformin after consultation with Dr and reevaluation of the need. next recheck due in May 2013
Reply the comment
Kenneth Cruthis (2 years ago):
I am seventy years old and in pretty good health, I am borderline type two diabetic. My doctor prescribed Metphormin and within a week I was passing multiple small kidney stones and after about a week , still passing stones, then I quit for a couple of weeks and the stones subsided, then I started taking the drug again and the stones started back up again, now I have had a history of stones in the past but nothing as frequent as this. I started taking 2000 mg. of Calcium each day and haven't been bothered with stones in several years until I started taking Metphormin. This is the only Generic drug that I know of for non insulin dependent diabetes. I may try it again for another test. I have decided that my health is my reasonability with loosing weight, diet and exercise.
Reply the comment
Wil (3 years ago):
I have been on Metformin 250mg twice daily for about 7 months. My first ever kidney stone event occured at 5 months with a second event at 7 months. Metformin was the replacement for Avandia which I had taken for years without incident. I am 68 years old.
Reply the comment
Kreese (3 years ago):
I was diagnosed Type 2 diabetic late 2010 and started onn Medformin 250 mg twice a day. very strange that my blood sugars were normal afdter 1 week on the meds and continued to be normal even after having a none fasting blood sugar and A1C done, which were all normal as well.
Recently I had kidney stones from hell and was rushed to the hospital after being on Medformin for 6 Months.
Being in the pharmaceutcal field I am convinced that Medformin causes Kidney Stones. Drug companies do not report all side affects from clinical trials to the FDA, this I can tell you they use the data that is good for them to get their dug approved. I am sure that the numbers are higher for people developing kidney stones from Medformin.
Reply the comment
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Do you have Kidney Stones while taking Metformin Hydrochloride?
You are not alone! Join a mobile support group:
- support group for people who take Metformin hydrochloride and have Kidney Stones
- support group for people who take Metformin hydrochloride
- support group for people who have Kidney Stones
Recent conversations of related support groups:
Drugs in real world that are associated with:
Could your condition cause:
Can you answer these questions (Ask a question):
- What drugs cause male breast enlargement
(Asked by a 62 year old man who has Hydrocele, Breast Enlargement, and takes Hydrochlorothiazide, Metformin)
At age 62 breast seam to enlarge over the last two years
- How to deal with low blood pressure caused by metformin
(Asked by a 75 year old man who has Low Blood Pressure, and takes Metformin)
I was on Accupril 5 mg for more than 10 years with little or no side effects. I was diagnosed with early Type 2 diabetes and the doctor prescribed Metformin 500 mg 2 tablets a day. After about 3 months, the blood pressure was too low 88 Sistolic 45 diastolic and suffered syncope.
I reduced Accupr ...
- Could prilosec cause an elevated blood sugar
(Asked by a 64 year old woman who has DIABETES, and takes Metformin, Prilosec)
I've been on Prilosec for about 1 month & my blood sugars have been elevated starting shortly after I started on it. could Prilosec be causing it? Nothing else has changed with my meds or lifestyle.
- Can cold sores cause bs to elevate?
(Asked by a 65 year old woman who has Unusually Long Time Suffering With Outbreaks Of Cold Sores. BS Always In Normal Limits Unless Sick?, and takes Metformin)
type 2 non insulin dependent DM. Having severe flu like symptoms when I get cold sore. BS never out of normal range except when I get cold sores!
- I have an enlarged liver...could i use buprenorphine?
(Asked by a 33 year old woman who has Enlarged Liver, and takes Allopurinol, Metformin, Lyrica, Morphine)
I want to know if i can take buprenorphine with an enlarged liver
More questions for: Metformin hydrochloride, Kidney stones
You may be interested at these reviews (Write a review):
- Hair loss with metformin hydrochloride usage
(Posted by a 58 year old woman who has Hair Loss, and takes Metformin Hydrochloride)
I have been taking the drug Metformin Hydrochloride for about 5 months and definitely find that I am losing hair which is a problem I have never experienced. Always had the healthiest hair, no problems. Well, I am finding that I am losing lair significantly and feel that the manufacturer of this dru ...
- Ranexa and erectile dysfunction
(Posted by a 67 year old man who has Metabolic Syndrome, Aortic Valve Replacement, Coronary Artery Disease, and takes Nitrostat, Acyclovir, Gabapentin, Hytrin, Metformin, Aspirin, Isosorbide Mononitrate, Ranexa, Hydrochlorothiazide, Carvedilol, Losartan Potassium)
I have experienced moderate ED with taking multiple heart and NO meds. This has been manageable and acceptable. Cardiologist added Ranexa (Ranalozine) 3 weeks ago and I am now experiencing complete erectile and ejaculatory failure.
- Victoza and liver cancer (cholangiocarcinoma)
(Posted by a 59 year old man who has Anaemia Vitamin B12 Deficiency, Sleep Apnea, Hypertension, Type 2 Diabetes Mellitus, Cholangiocarcinoma (liver Cancer), and takes Diovan, Atenolol, Metformin, Victoza)
My husband was recently diagnosed with stage 4 liver cancer after taking Victoza for several years. The doctor discontinued the Victoza when the cancer was diagnosed but he actually started feeling better after he stopped it until the cancer started progressing. Since cholangiocarcinoma nd pancreati ...
- Olfactory issues due to metformin use
(Posted by a 33 year old woman who has Infertility, and takes Metformin)
I've found that the metformin does not smell especially bad, but when I first started taking it, I could smell something horrible - to the point where I pulled apart my cupboards and fridge, fully expecting to find some maggot-riddled rotting meat. Eventually I realized I was smelling normal smel ...
- Metformin changes in mentrual cycle
(Posted by a 55 year old woman who has Menstrual Periods - Heavy, Prolonged, Or Irregular, Menopause Transition, and takes Metformin)
At age 55, I started to enter menopause. When it began to taper off a couple of years ago, only one ovary was functioning, and my periods lasted only 1-2 days with minimal flow. Hadn't had a period in 4 months. Still had some PMS symptoms, but no flow. Was prescribed Metformin for pre-diabetes. My ...
More reviews for: Metformin hydrochloride, Kidney stones
- A study of drug interactions between Atorvastatin Calcium, Losartan, Metformin, Glyburide, Bystolic, Pradaxa for a patient with High Blood Cholesterol, Blood Pressure, Diabetes, Diabetic Coma, Blood Pressure Increased, A-fib. The patient has Leg Cramping, Weakness
Comments: I stop pradaxa a week before having pain shot for lower back pain. I have no pain or weakness for about a week after going back on pradaxa. This has happended three times now. Can't say for sure the pradaxa is the cause or if that is the amount of time the pain shot last.
- A study of drug interactions between Omeprazole, Trazodone Hydrochloride, Wellbutrin Xl, Norco, Simvastatin, Tricor, Lisinopril, Metformin, Gabapentin, Phentermine, Topiramate for a patient with Acid Reflux, Depression, Pain, High Blood Cholesterol And Triglycerides, High Blood Pressure, Diabetes Mellitus Non-insulin-dependent, Inflammatory Pain, Weight Loss. The patient has Hair Loss
Comments: I had some hair thinning over the past 10+ years and was told it was due to HBP and medications. Since taking phentermine and topiramate for weight loss along with the other meds hair loss has tripled at a radical rate. I stopped taking topiramate about a month ago and still the hair keeps falling ...
- A study of drug interactions between Vitamin D, Vitamin E, Vitamin C, Potassium Gluconate, Butrans, Androgel, Viibryd, Livalo, Tribenzor, Nexium, Metformin, Lantus, Atenolol, Lovaza, Allopurinol for a patient with General Physical Health Deterioration, General Physical Condition, Muscle Weakness, Pain, Testosterone, Depression, High Blood Cholesterol And Triglycerides, High Blood Pressure, Gerd, Diabetes, High Blood Cholesterol, High Blood Sugar, Gout. The patient has Diabetes Mellitus, Erectile Dysfunction, Peripheral Neuropathy
Comments: Concern about allopurinol having exacerbated peripheral neuropathy
Also concerned about drugs and their interactions causing ED if I stop taking blood pressure meds incidence of ED is reduced considerably.
- A study of drug interactions between Flonase, Hydrocodone Bitartrate And Acetaminophen, Vyvanse, Metformin, Zyrtec, Omeprazole, Cymbalta for a patient with Multiple Allergies, Polymyalgia Rheumatica, Add, Insulin Resistance, Acid Reflux, Mood Disorder. The patient has Urinary Incontinence, Fatigue, Seborrhoeic Dermatitis
Comments: 10 yrs ago, suddenly had allergic reaction to shampoo and deodorant that I had used for years. Changed deodorants. Still have issues with scalp flare ups while using any brand shampoo. Only thing that helps is Head and Shoulders medicated shampoo in dark blue bottle.
- A study of drug interactions between Effexor Xr, Minocycline Hydrochloride, Klonopin, Lasix, Metformin, Levoxyl, Adderall 20, Trazodone Hydrochloride, Methocarbamol, Baclofen, Hydrocodone Bitartrate And Acetaminophen for a patient with Depression, Acne Cystic, Anxiety Disorder, Edema, Polycystic Ovarian Syndrome (pcos), Hypothyroidism, Add, Sleep Disorder, Neck Pain. The patient has
Comments: My WBC count has been low for 4mos now. I'm lethargic, having problems sleeping & still experiencing a tremendous amount of pain (which I believe it has to do with the congenital lipoma on my brain stem-I've had excruciating pain as long as I can remember.)
More related studies for: Metformin hydrochloride, Kidney stones
NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.