Review: could Metformin cause Kidney stones?
(By eHealthMe on Mar, 6, 2014)
Severity ratings: 3.0/4
On a scale of 1 to 4: 1=least, 2=moderate, 3=severe, 4=most severe
We study 12,522 people who take Metformin. Among them, 76 have Kidney stones. See who they are, when they have Kidney stones and more. This review is based on reports from FDA and social media, and is updated regularly.
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Metformin hydrochloride (latest outcomes from 14,573 users) has active ingredients of metformin hydrochloride. It is often used in diabetes, type 2 diabetes. Commonly reported side effects of Metformin hydrochloride include nausea aggravated, nausea, blood glucose increased, renal failure acute, lactic acidosis.
Kidney stones (latest reports from 103,194 patients) has been reported by people with multiple sclerosis, osteoporosis, high blood pressure, rheumatoid arthritis, pain.
On Mar, 6, 2014: 12,522 people reported to have side effects when taking Metformin hydrochloride. Among them, 76 people (0.61%) have Kidney Stones.
Time on Metformin hydrochloride when people have Kidney stones * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Kidney stones||0.00%||12.50%||0.00%||0.00%||25.00%||12.50%||50.00% |
Gender of people who have Kidney stones when taking Metformin hydrochloride * :
|Kidney stones||51.85%||48.15% |
Age of people who have Kidney stones when taking Metformin hydrochloride * :
|Kidney stones||0.00%||0.00%||0.00%||0.00%||5.66%||22.64%||39.62%||32.08% |
Severity of Kidney stones when taking Metformin hydrochloride ** :
|least||moderate||severe||most severe |
|Kidney stones||0.00%||0.00%||100.00%||0.00% |
How people recovered from Kidney stones ** :
|while on the drug||after off the drug||not yet |
|Kidney stones||0.00%||0.00%||100.00% |
Top conditions involved for these people * :
- Diabetes mellitus (17 people, 22.37%)
- Metastatic neoplasm (13 people, 17.11%)
- Type 2 diabetes mellitus (12 people, 15.79%)
- Breast cancer metastatic (11 people, 14.47%)
- Hypersensitivity (10 people, 13.16%)
Top co-used drugs for these people * :
- Aspirin (27 people, 35.53%)
- Zometa (23 people, 30.26%)
- Colace (19 people, 25.00%)
- Crestor (19 people, 25.00%)
- Insulin (18 people, 23.68%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
Comments for this study:
Wil (1 year ago):
UPDATE: August and September 2012 had Lithotripsy for two large stones. Also stopped Metformin after consultation with Dr and reevaluation of the need. next recheck due in May 2013
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Kenneth Cruthis (1 year ago):
I am seventy years old and in pretty good health, I am borderline type two diabetic. My doctor prescribed Metphormin and within a week I was passing multiple small kidney stones and after about a week , still passing stones, then I quit for a couple of weeks and the stones subsided, then I started taking the drug again and the stones started back up again, now I have had a history of stones in the past but nothing as frequent as this. I started taking 2000 mg. of Calcium each day and haven't been bothered with stones in several years until I started taking Metphormin. This is the only Generic drug that I know of for non insulin dependent diabetes. I may try it again for another test. I have decided that my health is my reasonability with loosing weight, diet and exercise.
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Wil (3 years ago):
I have been on Metformin 250mg twice daily for about 7 months. My first ever kidney stone event occured at 5 months with a second event at 7 months. Metformin was the replacement for Avandia which I had taken for years without incident. I am 68 years old.
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Kreese (3 years ago):
I was diagnosed Type 2 diabetic late 2010 and started onn Medformin 250 mg twice a day. very strange that my blood sugars were normal afdter 1 week on the meds and continued to be normal even after having a none fasting blood sugar and A1C done, which were all normal as well.
Recently I had kidney stones from hell and was rushed to the hospital after being on Medformin for 6 Months.
Being in the pharmaceutcal field I am convinced that Medformin causes Kidney Stones. Drug companies do not report all side affects from clinical trials to the FDA, this I can tell you they use the data that is good for them to get their dug approved. I am sure that the numbers are higher for people developing kidney stones from Medformin.
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Related topic: Metformin hydrochloride, Kidney stones
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On eHealthMe, Metformin Hydrochloride (metformin hydrochloride) is often used for diabetes. Find out below the conditions Metformin Hydrochloride is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.
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From this study (13 hours ago):
with Metformin I have stomach problems. if I lose body fluids I drink pedialyte I take metformin for type 2
I have taken more than 4 Met. prescribed because high blood sugar at times.
I have Black out suddenly or have spells of blackout with shacking and jerking.
I come to in a few seconds. (what happen I ask) They tell me I was uncontrolably jerking and making puffing sounds with my month.
My Heart can be racing 159/92 or as low as 78/41 but comes back to normal 120/70 range in about 5 min.
This started 1 year ago this March. Have been through every test from ears,blood,heart,thyroid,stomach medicines removed.
Now the only thing I still take every day is the metformin could that cause blackout/seziers? if you take when body fluids are low or take to much at a time?
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Believe my problem is with Formoterol. Symptoms (breathlessness and being winded with minimal exertion) first noted three years ago after taking Foradil aerolizer (formoterol) and asmanex twisthaler for one to two years. Health, stamina gradually dimished to shortness of breath with minimal exertion. One - two years ago prescription changed to symbicort. health improved dramatically for approximately two months. Began walking one to two miles a day. Now back to being winded with minimal exertion. Health seems better until I take my symbicort. Spiriva seems to counter act breathlessness at morning when I take with symbicort. At evening with no Spiriva, breathlessness prevails. using Spiriva twice daily works but doctor says no.
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