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Review: could Metformin cause Muscle atrophy?

Summary: Muscle atrophy could be caused by Metformin, especially for people who are male, 60+ old, have been taking the drug for 5 - 10 years, also take Simvastatin, and have Hypercholesterolaemia.

We study 12,739 people who have side effects while taking Metformin from FDA and social media. Among them, 8 have Muscle atrophy. Find out below who they are, when they have Muscle atrophy and more.

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Metformin hydrochloride

Metformin hydrochloride (latest outcomes from 14,580 users) has active ingredients of metformin hydrochloride. It is often used in diabetes.

Muscle atrophy

Muscle atrophy (a decrease in the mass of the muscle) (latest reports from 36,961 patients) has been reported by people with high blood cholesterol, high blood pressure, multiple sclerosis, osteoporosis, pain.

On Apr, 11, 2014: 12,527 people reported to have side effects when taking Metformin hydrochloride. Among them, 8 people (0.06%) have Muscle Atrophy. They amount to 0.02% of all the 36,890 people who have Muscle Atrophy on eHealthMe.

Trend of Muscle atrophy in Metformin hydrochloride reports

Time on Metformin hydrochloride when people have Muscle atrophy * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Muscle atrophy0.00%0.00%0.00%0.00%50.00%50.00%0.00%

Gender of people who have Muscle atrophy when taking Metformin hydrochloride * :

FemaleMale
Muscle atrophy0.00%100.00%

Age of people who have Muscle atrophy when taking Metformin hydrochloride * :

0-12-910-1920-2930-3940-4950-5960+
Muscle atrophy0.00%0.00%0.00%0.00%0.00%0.00%0.00%100.00%

Severity of Muscle atrophy when taking Metformin hydrochloride ** :

leastmoderateseveremost severe
Muscle atrophy0.00%100.00%0.00%0.00%

How people recovered from Muscle atrophy ** :

n/a

Top conditions involved for these people * :

  1. Hypercholesterolaemia (3 people, 37.50%)
  2. Myocardial infarction (2 people, 25.00%)
  3. Type 2 diabetes mellitus (2 people, 25.00%)
  4. Bph (1 people, 12.50%)
  5. Neuropathy (1 people, 12.50%)

Top co-used drugs for these people * :

  1. Simvastatin (4 people, 50.00%)
  2. Ramipril (3 people, 37.50%)
  3. Furosemide (1 people, 12.50%)
  4. Metolazone (1 people, 12.50%)
  5. All other therapeutic products (1 people, 12.50%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Metformin hydrochloride, Muscle atrophy

You can also:

On eHealthMe, Metformin Hydrochloride (metformin hydrochloride) is often used for diabetes. Find out below the conditions Metformin Hydrochloride is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Metformin Hydrochloride used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (6 months ago):

  • I've lost 70 lbs in two years, 40 lbs. in the past year. I am having significant atrophy in my legs, specifically my right leg. As a 52 year old man, I cannot walk normally nor can I walk up stairs.

    Reply

  • From this study (5 years ago):

  • Was never a smoker, but have intense cravings for cigarettes and seek to smoke 5-10 per day. Unusually/easily emotional. Highly agitated - take 5 or more walks per day to try to relieve the feeling. Significantly changed behavior and misses social cues, so may continue to repeat questions or opinions.

    Behavioral and physical changes came on seemingly all at once, not gradually over time.

    Reply

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Related study

- Metformin Hydrochloride side effects

 

Related symptom

- Muscle Atrophy

 

 

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