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Review: could Metformin cause Acid reflux?

Summary: Acid reflux could be caused by Metformin, especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years, also take Metformin hcl, and have Type 2 diabetes mellitus.

We study 97,041 people who have side effects while taking Metformin from FDA and social media. Among them, 140 have Acid reflux. Find out below who they are, when they have Acid reflux and more.

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On Apr, 11, 2014: 97,158 people reported to have side effects when taking Metformin. Among them, 140 people (0.14%) have Acid Reflux. They amount to 0.32% of all the 43,846 people who have Acid Reflux on eHealthMe.

Trend of Acid reflux in Metformin reports

Time on Metformin when people have Acid reflux * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Acid reflux10.00%23.33%16.67%3.33%20.00%23.33%3.33%

Gender of people who have Acid reflux when taking Metformin * :

FemaleMale
Acid reflux65.00%35.00%

Age of people who have Acid reflux when taking Metformin * :

0-12-910-1920-2930-3940-4950-5960+
Acid reflux0.00%0.00%0.00%3.01%4.51%18.80%30.08%43.61%

Severity of Acid reflux when taking Metformin ** :

leastmoderateseveremost severe
Acid reflux4.00%44.00%48.00%4.00%

How people recovered from Acid reflux ** :

while on the drugafter off the drugnot yet
Acid reflux7.69%30.77%61.54%

Top conditions involved for these people * :

  1. Type 2 diabetes mellitus (36 people, 25.71%)
  2. Hypertension (19 people, 13.57%)
  3. Depression (17 people, 12.14%)
  4. Diabetes mellitus non-insulin-dependent (13 people, 9.29%)
  5. Diabetes mellitus (13 people, 9.29%)

Top co-used drugs for these people * :

  1. Metformin hcl (75 people, 53.57%)
  2. Aspirin (34 people, 24.29%)
  3. Byetta (33 people, 23.57%)
  4. Metformin hydrochloride (29 people, 20.71%)
  5. Lisinopril (23 people, 16.43%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

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On eHealthMe, Metformin (metformin hydrochloride) is often used for diabetes. Find out below the conditions Metformin is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

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Comments from related studies:

  • From this study (3 months ago):

  • I have been on this for about 2months and seem to have the heartburn and acid reflux since the, I also feel uncomfortable under my ribs

    Reply

  • From this study (3 months ago):

  • Problems digesting food, bowel irregularity, blood in feces, blood from bowel, extreme bruising, reoccurring acid reflux, fatigue and muscle pain which interrupts physical exercise program.

    Reply

  • From this study (5 months ago):

  • I have been taking metformin for 4 years and started having reflux about 8 months ago. at the same time i switched from noritripiline to the brand name, pamalor. i now have a slightly bleeding ulcer on my larnyx and severe reflux.

    Reply

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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