Review: could Metformin cause Bladder Cancer?


Summary

Bladder cancer is found among people who take Metformin, especially for people who are male, 60+ old , have been taking the drug for 2 - 5 years, also take medication Actos, and have Type 2 diabetes mellitus . We study 84,420 people who have side effects while taking Metformin from FDA and social media. Among them, 1,702 have Bladder cancer. Find out below who they are, when they have Bladder cancer and more.

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Metformin

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin 174,670 users)

Bladder Cancer

Bladder cancer has been reported by people with death, thrombocytopenia, urinary tract infection, haematuria, fever (latest reports from 14,143 Bladder cancer patients).

On Sep, 21, 2016

84,420 people reported to have side effects when taking Metformin.
Among them, 1,702 people (2.02%) have Bladder Cancer


Number of reports submitted per year:

Could Metformin cause Bladder cancer?

Time on Metformin when people have Bladder Cancer *:

  • < 1 month: 0.41 %
  • 1 - 6 months: 6.4 %
  • 6 - 12 months: 5.58 %
  • 1 - 2 years: 15.29 %
  • 2 - 5 years: 32.23 %
  • 5 - 10 years: 27.07 %
  • 10+ years: 13.02 %

Gender of people who have Bladder Cancer when taking Metformin *:

  • female: 20.09 %
  • male: 79.91 %

Age of people who have Bladder Cancer when taking Metformin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.47 %
  • 20-29: 0.47 %
  • 30-39: 0.0 %
  • 40-49: 1.41 %
  • 50-59: 13.15 %
  • 60+: 84.51 %

Top conditions involved for these people *:

  • Type 2 Diabetes Mellitus (1,629 people, 95.71%)
  • Diabetes Mellitus (427 people, 25.09%)
  • Hypertension (20 people, 1.18%)
  • Pain (16 people, 0.94%)
  • Multiple Myeloma (14 people, 0.82%)

Top co-used drugs for these people *:

  • Actos (1,573 people, 92.42%)
  • Glucophage (559 people, 32.84%)
  • Glucotrol (518 people, 30.43%)
  • Januvia (460 people, 27.03%)
  • Lantus (406 people, 23.85%)

Top other side effects for these people *:

  • Death (190 people, 11.16%)
  • Haematuria (41 people, 2.41%)
  • Urinary Tract Infection (30 people, 1.76%)
  • Pain (22 people, 1.29%)
  • Dyspnoea (20 people, 1.18%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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