Metformin and Brain injury - from FDA reports


Summary

Brain injury is found among people who take Metformin, especially for people who are female, 60+ old , have been taking the drug for 1 - 6 months, also take medication Aspirin, and have Diabetes . We study 176,252 people who have side effects while taking Metformin from FDA. Among them, 1,467 have Brain injury. Find out below who they are, when they have Brain injury and more.

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Metformin

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin 183,350 users)

Brain Injury

Brain injury has been reported by people with multiple sclerosis, osteoporosis, rheumatoid arthritis, high blood pressure, depression (latest reports from 67,742 Brain injury patients).

On Feb, 16, 2017

176,252 people reported to have side effects when taking Metformin.
Among them, 1,467 people (0.83%) have Brain Injury


Number of reports submitted per year:

Could Metformin cause Brain injury?

Time on Metformin when people have Brain Injury *:

  • < 1 month: 19.15 %
  • 1 - 6 months: 27.66 %
  • 6 - 12 months: 14.89 %
  • 1 - 2 years: 10.64 %
  • 2 - 5 years: 14.89 %
  • 5 - 10 years: 10.64 %
  • 10+ years: 2.13 %

Gender of people who have Brain Injury when taking Metformin *:

  • female: 61.14 %
  • male: 38.86 %

Age of people who have Brain Injury when taking Metformin *:

  • 0-1: 0.0 %
  • 2-9: 0.09 %
  • 10-19: 0.43 %
  • 20-29: 1.37 %
  • 30-39: 2.58 %
  • 40-49: 8.84 %
  • 50-59: 20.69 %
  • 60+: 65.92 %

Top conditions involved for these people *:

  • Diabetes (358 people, 24.40%)
  • Type 2 Diabetes (223 people, 15.20%)
  • High Blood Pressure (222 people, 15.13%)
  • High Blood Cholesterol (167 people, 11.38%)
  • Atrial Fibrillation/flutter (114 people, 7.77%)

Top co-used drugs for these people *:

  • Aspirin (225 people, 15.34%)
  • Lisinopril (153 people, 10.43%)
  • Lipitor (146 people, 9.95%)
  • Lasix (136 people, 9.27%)
  • Lantus (136 people, 9.27%)

Top other side effects for these people *:

  • Fall (592 people, 40.35%)
  • Pain (236 people, 16.09%)
  • Fatigue (221 people, 15.06%)
  • Dizziness (207 people, 14.11%)
  • Nausea (206 people, 14.04%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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