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Review: could Metformin cause Brain injury?

We study 97,185 people who have side effects while taking Metformin from FDA and social media. Among them, 750 have Brain injury. Find out below who they are, when they have Brain injury and more.

Stay connected: get help anytime and anywhere for people who take Metformin and have Brain injury >>>

Metformin

Metformin (latest outcomes from 100,693 users) has active ingredients of metformin hydrochloride. It is often used in type 2 diabetes.

Brain injury

Brain injury (latest reports from 259,717 patients) has been reported by people with osteoporosis, multiple sclerosis, rheumatoid arthritis, high blood pressure, depression.

On Jul, 18, 2014: 97,167 people reported to have side effects when taking Metformin. Among them, 750 people (0.77%) have Brain Injury. They amount to 0.29% of all the 259,616 people who have Brain Injury on eHealthMe.

Trend of Brain injury in Metformin reports

Time on Metformin when people have Brain injury * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Brain injury0.00%25.00%4.17%12.50%33.33%25.00%0.00%

Gender of people who have Brain injury when taking Metformin * :

FemaleMale
Brain injury64.80%35.20%

Age of people who have Brain injury when taking Metformin * :

0-12-910-1920-2930-3940-4950-5960+
Brain injury0.00%0.15%0.30%1.52%1.52%11.11%24.96%60.43%

Severity of Brain injury when taking Metformin ** :

n/a

How people recovered from Brain injury ** :

n/a

Top conditions involved for these people * :

  1. Diabetes mellitus (202 people, 26.93%)
  2. Hypertension (124 people, 16.53%)
  3. Type 2 diabetes mellitus (94 people, 12.53%)
  4. Breast cancer metastatic (65 people, 8.67%)
  5. Blood cholesterol increased (59 people, 7.87%)

Top co-used drugs for these people * :

  1. Metformin hcl (560 people, 74.67%)
  2. Aspirin (285 people, 38.00%)
  3. Lasix (132 people, 17.60%)
  4. Avandia (121 people, 16.13%)
  5. Metformin hydrochloride (114 people, 15.20%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Comments from related studies:

  • From this study (3 days ago):

  • For past month have been getting sudden horrible "charley horse" muscle cramps in both legs in the late afternoon and evenings

    Reply

  • From this study (6 days ago):

  • I only took the Celebrex (1 pill) yesterday in a.m., took the Levothyroxine and HCTZ and took 1/2 of Flexeril (a 5 mg tab - 2.5 mg after cut in half) at bedtime. No Ultracet taken yesterday. Was awakened in middle of night wetting myself. Underwear and PJs had a very strong smell of ammonia, which is not usual for me. Concerned about the odor.

    Reply

    Em on Jun, 23, 2014:

    HCTZ is a diuretic and should be taken in the morning.
    You need to drink more water or you will continue to have
    The odor of ammonia in your urine. The urine is concentrating in your bladder during the day and then when the HCTZ kicks in, you're urine is concentrated. You probably wet the bed because you were in very deep sleep and/or dreaming. This with the diuretic is a bad combination. To be safe ask your physician or pharmacist about the best time to take the HCTZ and tell your doctor about the odor of ammonia in your urine. I am not a primary care provider but have been a nurse for 27 years and have an MS degree so my advice and information are probably accurate but are not to be considered MEDICAL ADVICE. This information is only provided to assist you in discussing your medication and symptom, with a primary care provider (MD,DO, PA, FNP, NP. CNS...) and your pharmacist.

    Reply

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On eHealthMe, Metformin (metformin hydrochloride) is often used for diabetes. Find out below the conditions Metformin is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Metformin used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

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