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Review: could Metformin cause Brain injury?

Summary: Brain injury could be caused by Metformin, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take Metformin hcl, and have Diabetes mellitus.

We study 97,041 people who have side effects while taking Metformin from FDA and social media. Among them, 750 have Brain injury. Find out below who they are, when they have Brain injury and more.

On Apr, 5, 2014: 97,138 people reported to have side effects when taking Metformin. Among them, 750 people (0.77%) have Brain Injury. They amount to 0.29% of all the 255,621 people who have Brain Injury on eHealthMe.

Trend of Brain injury in Metformin reports

Time on Metformin when people have Brain injury * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Brain injury0.00%25.00%4.17%12.50%33.33%25.00%0.00%

Gender of people who have Brain injury when taking Metformin * :

FemaleMale
Brain injury64.80%35.20%

Age of people who have Brain injury when taking Metformin * :

0-12-910-1920-2930-3940-4950-5960+
Brain injury0.00%0.15%0.30%1.52%1.52%11.11%24.96%60.43%

Severity of Brain injury when taking Metformin ** :

n/a

How people recovered from Brain injury ** :

n/a

Top conditions involved for these people * :

  1. Diabetes mellitus (202 people, 26.93%)
  2. Hypertension (124 people, 16.53%)
  3. Type 2 diabetes mellitus (94 people, 12.53%)
  4. Breast cancer metastatic (65 people, 8.67%)
  5. Blood cholesterol increased (59 people, 7.87%)

Top co-used drugs for these people * :

  1. Metformin hcl (560 people, 74.67%)
  2. Aspirin (285 people, 38.00%)
  3. Lasix (132 people, 17.60%)
  4. Avandia (121 people, 16.13%)
  5. Metformin hydrochloride (114 people, 15.20%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Metformin, Brain injury

You can also:

On eHealthMe, Metformin (metformin hydrochloride) is often used for diabetes. Find out below the conditions Metformin is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Metformin used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (23 hours ago):

  • have had a history of acute pancreatitis with 11000 lipase after gallbladder removal. Did have biliary sludge.

    Reply

  • From this study (1 day ago):

  • i am taking these medicines for proteinurea but since last 1-2 weeks i'm having trouble breathing sometimes.

    Reply

  • From this study (2 days ago):

  • Have been on Metformin for just under 2 weeks. Stopped taking it today as since I began taking it, I have noticed mood swings, memory and cognitive impairment and a huge increase in paranoia and anxiety.

    Reply

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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