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Review: could Metformin cause Constipation?





Summary: Constipation is found among people who take Metformin, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Metformin hcl, and have Diabetes mellitus.

We study 97,386 people who have side effects while taking Metformin from FDA and social media. Among them, 1,586 have Constipation. Find out below who they are, when they have Constipation and more.

You are not alone: join a mobile support group for people who take Metformin and have Constipation >>>

Metformin

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (view latest outcomes from 100,893 users)

Constipation

Constipation has been reported by people with osteoporosis, pain, high blood pressure, depression, high blood cholesterol.(latest reports from Constipation 80,049 patients)

On Nov, 25, 2014: 97,351 people reported to have side effects when taking Metformin. Among them, 1,588 people (1.63%) have Constipation.

Trend of Constipation in Metformin reports

Time on Metformin when people have Constipation * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Constipation6.38%38.30%4.26%8.51%14.89%23.40%4.26%

Gender of people who have Constipation when taking Metformin * :

FemaleMale
Constipation55.38%44.62%

Age of people who have Constipation when taking Metformin * :

0-12-910-1920-2930-3940-4950-5960+
Constipation0.00%0.00%0.43%0.50%4.62%10.74%23.54%60.17%

Severity of Constipation when taking Metformin ** :

leastmoderateseveremost severe
Constipation4.55%45.45%36.36%13.64%

How people recovered from Constipation ** :

while on the drugafter off the drugnot yet
Constipation9.09%27.27%63.64%

Top conditions involved for these people * :

  1. Diabetes mellitus (324 people, 20.40%)
  2. Type 2 diabetes mellitus (276 people, 17.38%)
  3. Diabetes mellitus non-insulin-dependent (177 people, 11.15%)
  4. Hypertension (157 people, 9.89%)
  5. Pain (78 people, 4.91%)

Top co-used drugs for these people * :

  1. Metformin hcl (1,108 people, 69.77%)
  2. Byetta (418 people, 26.32%)
  3. Aspirin (407 people, 25.63%)
  4. Lisinopril (240 people, 15.11%)
  5. Lantus (179 people, 11.27%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Constipation while taking Metformin?

You are not alone! Join a mobile support group:
- support group for people who take Metformin and have Constipation
- support group for people who take Metformin
- support group for people who have Constipation

Drugs in real world that are associated with:

Could your condition cause:

Can you answer these questions (Ask a question):

  • Cymbalta r/t autonomic neuropathy
    (Asked by a 62 year old man who has Stomach Pains, GERD, Fatique, Constipation, Dizzness, Early Satiety)
    neurotin
    losartan 20 mg
    tired all the time, dizziness, chronic constipation, stomach pains, pins and needles, diabetic type 2 hx alcoholism resolved, gerd, early satiety
  • What drugs cause male breast enlargement (2 answers)
    (Asked by a 62 year old man who has Hydrocele, Breast Enlargement, and takes Hydrochlorothiazide, Metformin)
    At age 62 breast seam to enlarge over the last two years
  • How to deal with low blood pressure caused by metformin
    (Asked by a 75 year old man who has Low Blood Pressure, and takes Metformin)
    I was on Accupril 5 mg for more than 10 years with little or no side effects. I was diagnosed with early Type 2 diabetes and the doctor prescribed Metformin 500 mg 2 tablets a day. After about 3 months, the blood pressure was too low 88 Sistolic 45 diastolic and suffered syncope.

    I reduced Accupril until I am completely off Accupril. Still the BP was too low and I then reduced Metformin to one tab a day. The BP came back and gradually became too high , i.e., 150/92. I have to put Accupril back on at 5/2 mg then 5/4 mg then finally at 5/8 mg. This seems to be optimal but the Blood Sugar is at just above 100, sometimes 106. I wish to increase Metformin back to 2 a day but afraid Bp will become too low.

    Any input would be appreciated.
  • Could prilosec cause an elevated blood sugar
    (Asked by a 64 year old woman who has DIABETES, and takes Metformin, Prilosec)
    I've been on Prilosec for about 1 month & my blood sugars have been elevated starting shortly after I started on it. could Prilosec be causing it? Nothing else has changed with my meds or lifestyle.
  • Can cold sores cause bs to elevate?
    (Asked by a 65 year old woman who has Unusually Long Time Suffering With Outbreaks Of Cold Sores. BS Always In Normal Limits Unless Sick?, and takes Metformin)
    type 2 non insulin dependent DM. Having severe flu like symptoms when I get cold sore. BS never out of normal range except when I get cold sores!

More questions for: Metformin, Constipation

You may be interested at these reviews (Write a review):

  • Hair loss with metformin hydrochloride usage
    (Posted by a 58 year old woman who has Hair Loss, and takes Metformin Hydrochloride)
    I have been taking the drug Metformin Hydrochloride for about 5 months and definitely find that I am losing hair which is a problem I have never experienced. Always had the healthiest hair, no problems. Well, I am finding that I am losing lair significantly and feel that the manufacturer of this drug should post that this is a side effect as so many have been complaining of the same side effect. I also began having problems with my teeth and always prided myself of having great teeth with no problems. I also understand that if there is a deficiency of Vitamin B12 that this together with taking this drug can cause these issues of hair loss and mouth/teeth problems. Again; I feel this should be totally and more readily informed to anyone taking this drug. I don't feel that anyone should have to give up things important to them to maintain a healthy way of living...I am going to see my physician and discuss what other options that may exist as I am not feeling very comfortable with this drug and the side effects I am experiencing.
  • Ranexa and erectile dysfunction
    (Posted by a 67 year old man who has Metabolic Syndrome, Aortic Valve Replacement, Coronary Artery Disease, and takes Nitrostat, Acyclovir, Gabapentin, Hytrin, Metformin, Aspirin, Isosorbide Mononitrate, Ranexa, Hydrochlorothiazide, Carvedilol, Losartan Potassium)
    I have experienced moderate ED with taking multiple heart and NO meds. This has been manageable and acceptable. Cardiologist added Ranexa (Ranalozine) 3 weeks ago and I am now experiencing complete erectile and ejaculatory failure.
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    (Posted by a 59 year old man who has Anaemia Vitamin B12 Deficiency, Sleep Apnea, Hypertension, Type 2 Diabetes Mellitus, Cholangiocarcinoma (liver Cancer), and takes Diovan, Atenolol, Metformin, Victoza)
    My husband was recently diagnosed with stage 4 liver cancer after taking Victoza for several years. The doctor discontinued the Victoza when the cancer was diagnosed but he actually started feeling better after he stopped it until the cancer started progressing. Since cholangiocarcinoma nd pancreatic cancer are similar, is there a link between Victoza and cholangiocarcinoma?
  • Nexium improves my constipation
    (Posted by a 53 year old woman who has Constipation, GERD, and takes Lyrica, Methadone Hydrochloride, Lipitor)
    Started taking Nexium 1 week ago and I noticed improvement with my chronic constipation.
  • I need advise, badly ckd!! (1 response)
    (Posted by a 49 year old woman who has Constipation, Peripheral Neuropathy, Orthostatic Hypotension, Chronic Kidney Disease, and takes Milk Thistle, Zolpidem, Melatonin, Xanax, Adderall 30, Zorvolex)
    The orthostatic BP started in mid April, I was only dizzy upon wakening then it would subside. I have never been a big breakfast eater so I started doing that. We were in Disney later in April and I was extremely fatigued, to the point of not wanting to walk, Disney would be the first time I passed out when getting dizzy. I of course said I had gotten too warm and was exhausted from work the previous week. The dizziness continued in the mornings & I passed out several more times. On May 1st, I passed out while putting my make-up on and hit my eye on the faucet and head on the tile floor, despite that I went to work thinking it would subside, it didn't. I went to the ER directly after work. They ran a B-met on me and my GFR was 11 and creatinine 3.95. They admitted me to a larger hospital for evaluation. While in there, they pumped me with fluids continuously, saying I had severe dehydration. My kidney function improved, my creatinine levels went back down to 1.34. After 5 days I was discharged and told to see a cardiologist and endo. The endo doc cancelled my appointment on the basis it was not his area. I had had a cortisol and ACTH testing which I guess was normal. I saw the cardiologist, who said it wasn't cardio. I had had an echocardiogram in the hospital and EKG monitoring. Cardio sent me to neurology, the PNRN did a basic neurological exam and drew blood for disease markers such as Lupus, sjorgens, hepatitis, ect. All disease markers came back negative, but my GFR was at 11 again and creatinine was 4.25, BUN 50 along with an elevated ACE level. They called me and said I sarcoidosis. I really don't have any of the primary S/S of this autoimmune disease. I don't know where to go from here, they are referring me to another neurologist at a bigger hospital. I can't live my normal life, can't walk on my feet due extreme pain and I pass out at least 2x a week, which is not good for my old body. My BP upon laying and sitting runs like 117/72, upon standing it drops to like 70/50-50/30. I am on 0.1 mg of florinef, I tried increasing it but then my legs swelled up for a gain of 23#. I talked to Mayo Clinic today and all there specialists are booked out thru December. I have to be able to work, I can't stay home any longer than September 8th! Please advise me!

More reviews for: Metformin, Constipation

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More related studies for: Metformin, Constipation

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