Could Metformin cause Constipation - from FDA reports


Summary

Constipation is found among people who take Metformin, especially for people who are female, 60+ old , have been taking the drug for 1 - 6 months, also take medication Byetta, and have Diabetes . We study 91,597 people who have side effects while taking Metformin from FDA. Among them, 1,260 have Constipation. Find out below who they are, when they have Constipation and more.

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Metformin

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin 183,204 users)

Constipation

Constipation has been reported by people with osteoporosis, pain, high blood pressure, multiple myeloma, multiple sclerosis (latest reports from 135,352 Constipation patients).

On Nov, 24, 2016

91,597 people reported to have side effects when taking Metformin.
Among them, 1,260 people (1.38%) have Constipation


Number of reports submitted per year:

Could Metformin cause Constipation?

Time on Metformin when people have Constipation *:

  • < 1 month: 10.26 %
  • 1 - 6 months: 20.51 %
  • 6 - 12 months: 12.82 %
  • 1 - 2 years: 12.82 %
  • 2 - 5 years: 15.38 %
  • 5 - 10 years: 17.95 %
  • 10+ years: 10.26 %

Gender of people who have Constipation when taking Metformin *:

  • female: 57.02 %
  • male: 42.98 %

Age of people who have Constipation when taking Metformin *:

  • 0-1: 0.0 %
  • 2-9: 0.11 %
  • 10-19: 0.32 %
  • 20-29: 0.95 %
  • 30-39: 4.53 %
  • 40-49: 8.95 %
  • 50-59: 23.68 %
  • 60+: 61.47 %

Severity of Constipation **:

  • least: 0.0 %
  • moderate: 50.0 %
  • severe: 33.33 %
  • most severe: 16.67 %

Top conditions involved for these people *:

  • Diabetes (319 people, 25.32%)
  • Type 2 Diabetes (308 people, 24.44%)
  • High Blood Pressure (215 people, 17.06%)
  • High Blood Cholesterol (151 people, 11.98%)
  • Pain (95 people, 7.54%)

Top co-used drugs for these people *:

  • Byetta (134 people, 10.63%)
  • Lipitor (112 people, 8.89%)
  • Lisinopril (100 people, 7.94%)
  • Lantus (100 people, 7.94%)
  • Januvia (99 people, 7.86%)

Top other side effects for these people *:

  • Nausea (346 people, 27.46%)
  • Diarrhea (238 people, 18.89%)
  • Fatigue (226 people, 17.94%)
  • Nausea And Vomiting (191 people, 15.16%)
  • Weight Decreased (171 people, 13.57%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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