Review: could Metformin cause Coronary Heart Disease?


Summary

Coronary heart disease is found among people who take Metformin, especially for people who are male, 60+ old , have been taking the drug for 2 - 5 years, also take medication Avandia, and have Diabetes mellitus . We study 37,644 people who have side effects while taking Metformin from FDA and social media. Among them, 401 have Coronary heart disease. Find out below who they are, when they have Coronary heart disease and more.

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Metformin

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin 117,555 users)

Coronary Heart Disease

Coronary heart disease (narrowing or blockage of the coronary arteries) has been reported by people with breathing difficulty, hypotension, renal failure acute, diarrhea, pneumonia (latest reports from 32,295 Coronary heart disease patients).

On Aug, 18, 2016

37,644 people reported to have side effects when taking Metformin.
Among them, 401 people (1.07%) have Coronary Heart Disease


Number of reports submitted per year:

Could Metformin cause Coronary heart disease?

Time on Metformin when people have Coronary Heart Disease *:

  • < 1 month: 4.35 %
  • 1 - 6 months: 4.35 %
  • 6 - 12 months: 4.35 %
  • 1 - 2 years: 30.43 %
  • 2 - 5 years: 39.13 %
  • 5 - 10 years: 17.39 %
  • 10+ years: 0.0 %

Gender of people who have Coronary Heart Disease when taking Metformin *:

  • female: 39.75 %
  • male: 60.25 %

Age of people who have Coronary Heart Disease when taking Metformin *:

  • 0-1: 0.28 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.85 %
  • 30-39: 2.54 %
  • 40-49: 14.37 %
  • 50-59: 33.24 %
  • 60+: 48.73 %

Severity if Coronary Heart Disease when taking Metformin **:

  • least: 0.0 %
  • moderate: 100 %
  • severe: 0.0 %
  • most severe: 0.0 %

How people recovered from Coronary Heart Disease **:

  • while on drug: 0.0 %
  • after off the drug: 0.0 %
  • not yet: 100 %

Top conditions involved for these people *:

  • Diabetes Mellitus (128 people)
  • Type 2 Diabetes Mellitus (56 people)
  • Hypertension (26 people)
  • Osteoporosis (11 people)
  • Rheumatoid Arthritis (10 people)

Top co-used drugs for these people *:

  • Avandia (248 people)
  • Lisinopril (101 people)
  • Lipitor (94 people)
  • Aspirin (93 people)
  • Avandamet (80 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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