Metformin and Coronary heart disease - from FDA reports


Summary

Coronary heart disease is found among people who take Metformin, especially for people who are male, 60+ old , have been taking the drug for 2 - 5 years, also take medication Avandia, and have Diabetes . We study 176,252 people who have side effects while taking Metformin from FDA. Among them, 1,561 have Coronary heart disease. Find out below who they are, when they have Coronary heart disease and more.

What to expect?

If you take Metformin and have Coronary heart disease, find out what symptoms you could have in 1 year or longer.

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Metformin

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin 183,363 users)

Coronary Heart Disease

Coronary heart disease (narrowing or blockage of the coronary arteries) has been reported by people with diabetes, arthritis, high blood pressure, type 2 diabetes, osteoporosis (latest reports from 45,040 Coronary heart disease patients).

On Jan, 31, 2017

176,252 people reported to have side effects when taking Metformin.
Among them, 1,561 people (0.89%) have Coronary Heart Disease


Number of reports submitted per year:

Could Metformin cause Coronary heart disease?

Time on Metformin when people have Coronary Heart Disease *:

  • < 1 month: 3.61 %
  • 1 - 6 months: 4.82 %
  • 6 - 12 months: 3.61 %
  • 1 - 2 years: 28.92 %
  • 2 - 5 years: 36.14 %
  • 5 - 10 years: 19.28 %
  • 10+ years: 3.61 %

Gender of people who have Coronary Heart Disease when taking Metformin *:

  • female: 36.95 %
  • male: 63.05 %

Age of people who have Coronary Heart Disease when taking Metformin *:

  • 0-1: 0.08 %
  • 2-9: 0.0 %
  • 10-19: 0.08 %
  • 20-29: 0.53 %
  • 30-39: 2.5 %
  • 40-49: 13.79 %
  • 50-59: 33.11 %
  • 60+: 49.92 %

Top conditions involved for these people *:

  • Diabetes (537 people, 34.40%)
  • Type 2 Diabetes (276 people, 17.68%)
  • High Blood Pressure (132 people, 8.46%)
  • High Blood Cholesterol (71 people, 4.55%)
  • Depression (48 people, 3.07%)

Top co-used drugs for these people *:

  • Avandia (854 people, 54.71%)
  • Aspirin (348 people, 22.29%)
  • Lisinopril (344 people, 22.04%)
  • Lipitor (327 people, 20.95%)
  • Avandamet (240 people, 15.37%)

Top other side effects for these people *:

  • Heart Attack (731 people, 46.83%)
  • Cardiac Failure Congestive (469 people, 30.04%)
  • High Blood Pressure (275 people, 17.62%)
  • Chest Pain (218 people, 13.97%)
  • Pain (210 people, 13.45%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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