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Review: could Metformin cause Heart attack?

Summary: Heart attack could be caused by Metformin, especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years, also take Metformin hcl, and have Diabetes mellitus.

We study 97,056 people who have side effects while taking Metformin from FDA and social media. Among them, 3,322 have Heart attack. Find out below who they are, when they have Heart attack and more.

How are my drugs for patients like me? On eHealthMe, you can research 300 million drug outcomes from FDA and social media. All studies are personalized to gender and age. Start now, it's anonymous, simple & free >>>

Metformin

Metformin (latest outcomes from 100,539 users) has active ingredients of metformin hydrochloride. It is often used in diabetes.

Heart attack

Heart attack (latest reports from 629,770 patients) has been reported by people with diabetes, arthritis, pain, acupuncture and pain, high blood pressure.

On Apr, 7, 2014: 97,138 people reported to have side effects when taking Metformin. Among them, 3,322 people (3.42%) have Heart Attack. They amount to 0.53% of all the 628,891 people who have Heart Attack on eHealthMe.

Trend of Heart attack in Metformin reports

Time on Metformin when people have Heart attack * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Heart attack2.27%11.36%6.82%22.27%32.27%19.09%5.91%

Gender of people who have Heart attack when taking Metformin * :

FemaleMale
Heart attack38.01%61.99%

Age of people who have Heart attack when taking Metformin * :

0-12-910-1920-2930-3940-4950-5960+
Heart attack0.00%0.00%0.03%0.36%2.95%14.59%31.76%50.31%

Severity of Heart attack when taking Metformin ** :

n/a

How people recovered from Heart attack ** :

n/a

Top conditions involved for these people * :

  1. Diabetes mellitus (895 people, 26.94%)
  2. Type 2 diabetes mellitus (403 people, 12.13%)
  3. Hypertension (186 people, 5.60%)
  4. Pain (64 people, 1.93%)
  5. Depression (62 people, 1.87%)

Top co-used drugs for these people * :

  1. Metformin hcl (2,149 people, 64.69%)
  2. Avandia (1,703 people, 51.26%)
  3. Aspirin (780 people, 23.48%)
  4. Lisinopril (654 people, 19.69%)
  5. Lipitor (579 people, 17.43%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Metformin, Heart attack

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On eHealthMe, Metformin (metformin hydrochloride) is often used for diabetes. Find out below the conditions Metformin is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Metformin used for and how effective is it:

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Comments from related studies:

  • From this study (4 days ago):

  • Recently Dxd w/ toxic multinodular goiter/hyperthyroidism. Fibromyalgia for 20+ years. Had to titrate off Savella 100 mg. BID due to hyperthyroidism. Now all above symptoms have worsened. Because thyroid blood work was in normal range ( although I had been on low iodine diet for 2 months, which should keep in normal range) endocrinologist said see me in six months! No instructions, no explanations. Can't find much about Plummer's online! Had bad reaction during uptake scan & ER said due to RAI. If levels had been high on blood work following scan results, Dr wanted to do RAI Ablation. I am a.) Afraid of worse reaction; b.) Ablation not working, having to be repeated; c.) Ultimately having to have thyroid removed surgically.
    I need to know my options! What should I be doing now? Anger and aggression, plus crying all the time are taking over my life. Savella was like a miracle drug for my fibromyalgia, but since it was an SNRI I am wondering how much of my problems is from stopping that. I did titrate off professionally, but had been on it over 3 years. Also wondering if it, hyperthyroidism or both are reason I am on four bp meds as cardiologist says heart is healthy. No history of stroke or seizures.
    Is there anyone out there who can give me direction? Every day is worse. Also having injections in c- spine to determine if neurological surgery w/ help w/ spinal cord compression. First was done Monday.
    Eyes also not focusing! Fibromyalgia or hyperthyroidism? Dr says I have 20/20 in each eye individually & field vision test okay. Still can't see TV or anything up close such as cosmetic needs for face! Nothing helps close vision. Glasses will help distance clear enough for now.

    Reply

  • From this study (5 days ago):

  • Cardiac triple bypass surgery on 13January 2009.

    Reply

  • From this study (7 days ago):

  • have had a history of acute pancreatitis with 11000 lipase after gallbladder removal. Did have biliary sludge.

    Reply

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