Metformin and Joint pain - from FDA reports


Summary

Joint pain is found among people who take Metformin, especially for people who are female, 60+ old , have been taking the drug for 1 - 6 months, also take medication Humira, and have Diabetes . We study 176,252 people who have side effects while taking Metformin from FDA. Among them, 3,642 have Joint pain. Find out below who they are, when they have Joint pain and more.

What to expect?

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Metformin

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin 183,350 users)

Joint Pain

Joint pain has been reported by people with rheumatoid arthritis, osteoporosis, high blood pressure, psoriatic arthropathy, high blood cholesterol (latest reports from 207,349 Joint pain patients).

On Jan, 27, 2017

176,252 people reported to have side effects when taking Metformin.
Among them, 3,642 people (2.07%) have Joint Pain


Number of reports submitted per year:

Could Metformin cause Joint pain?

Time on Metformin when people have Joint Pain *:

  • < 1 month: 19.7 %
  • 1 - 6 months: 30.3 %
  • 6 - 12 months: 9.09 %
  • 1 - 2 years: 6.06 %
  • 2 - 5 years: 16.67 %
  • 5 - 10 years: 16.67 %
  • 10+ years: 1.52 %

Gender of people who have Joint Pain when taking Metformin *:

  • female: 63.4 %
  • male: 36.6 %

Age of people who have Joint Pain when taking Metformin *:

  • 0-1: 0.11 %
  • 2-9: 0.04 %
  • 10-19: 0.53 %
  • 20-29: 0.88 %
  • 30-39: 4.33 %
  • 40-49: 12.07 %
  • 50-59: 29.78 %
  • 60+: 52.27 %

Top conditions involved for these people *:

  • Diabetes (913 people, 25.07%)
  • Rheumatoid Arthritis (560 people, 15.38%)
  • High Blood Pressure (548 people, 15.05%)
  • High Blood Cholesterol (516 people, 14.17%)
  • Type 2 Diabetes (429 people, 11.78%)

Top co-used drugs for these people *:

  • Humira (534 people, 14.66%)
  • Aspirin (483 people, 13.26%)
  • Lisinopril (396 people, 10.87%)
  • Lipitor (358 people, 9.83%)
  • Methotrexate (328 people, 9.01%)

Top other side effects for these people *:

  • Pain In Extremity (763 people, 20.95%)
  • Pain (690 people, 18.95%)
  • Fatigue (657 people, 18.04%)
  • Back Pain (552 people, 15.16%)
  • Nausea (550 people, 15.10%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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