Metformin and Kidney failure - from FDA reports


Summary

Kidney failure is found among people who take Metformin, especially for people who are male, 60+ old , have been taking the drug for 2 - 5 years, also take medication Aspirin, and have Type 2 diabetes . We study 176,252 people who have side effects while taking Metformin from FDA. Among them, 2,952 have Kidney failure. Find out below who they are, when they have Kidney failure and more.

What to expect?

If you take Metformin and have Kidney failure, find out what symptoms you could have in 1 year or longer.

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Metformin

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin 183,363 users)

Kidney Failure

Kidney failure (loss of kidney function) has been reported by people with high blood pressure, multiple myeloma, coronary artery bypass, diabetes, rheumatoid arthritis (latest reports from 82,171 Kidney failure patients).

On Feb, 03, 2017

176,252 people reported to have side effects when taking Metformin.
Among them, 2,952 people (1.67%) have Kidney Failure


Number of reports submitted per year:

Could Metformin cause Kidney failure?

Time on Metformin when people have Kidney Failure *:

  • < 1 month: 10.7 %
  • 1 - 6 months: 19.79 %
  • 6 - 12 months: 10.16 %
  • 1 - 2 years: 16.04 %
  • 2 - 5 years: 24.6 %
  • 5 - 10 years: 5.88 %
  • 10+ years: 12.83 %

Gender of people who have Kidney Failure when taking Metformin *:

  • female: 48.28 %
  • male: 51.72 %

Age of people who have Kidney Failure when taking Metformin *:

  • 0-1: 0.13 %
  • 2-9: 0.08 %
  • 10-19: 0.29 %
  • 20-29: 1.13 %
  • 30-39: 3.02 %
  • 40-49: 9.2 %
  • 50-59: 20.79 %
  • 60+: 65.31 %

Top conditions involved for these people *:

  • Type 2 Diabetes (659 people, 22.32%)
  • Diabetes (622 people, 21.07%)
  • High Blood Pressure (398 people, 13.48%)
  • High Blood Cholesterol (149 people, 5.05%)
  • Coronary Artery Bypass (133 people, 4.51%)

Top co-used drugs for these people *:

  • Aspirin (391 people, 13.25%)
  • Lisinopril (352 people, 11.92%)
  • Lasix (320 people, 10.84%)
  • Simvastatin (255 people, 8.64%)
  • Furosemide (253 people, 8.57%)

Top other side effects for these people *:

  • Lactic Acidosis (534 people, 18.09%)
  • Nausea And Vomiting (350 people, 11.86%)
  • Diarrhea (330 people, 11.18%)
  • Hypotension (314 people, 10.64%)
  • Dehydration (305 people, 10.33%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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