Review: could Metformin cause Kidney Failure?


Summary

Kidney failure is found among people who take Metformin, especially for people who are male, 60+ old , have been taking the drug for 2 - 5 years, also take medication Lasix, and have Type 2 diabetes mellitus . We study 84,423 people who have side effects while taking Metformin from FDA and social media. Among them, 1,035 have Kidney failure. Find out below who they are, when they have Kidney failure and more.

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 86 million people have used us. 300+ peer-reviewed medical journals have referenced our original studies. Start now >>>

Metformin

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin 174,670 users)

Kidney Failure

Kidney failure (loss of kidney function) has been reported by people with breathing difficulty, hypotension, acute kidney failure, sepsis, pneumonia (latest reports from 80,375 Kidney failure patients).

On Sep, 23, 2016

84,423 people reported to have side effects when taking Metformin.
Among them, 1,035 people (1.23%) have Kidney Failure


Number of reports submitted per year:

Could Metformin cause Kidney failure?

Time on Metformin when people have Kidney Failure *:

  • < 1 month: 8.82 %
  • 1 - 6 months: 17.65 %
  • 6 - 12 months: 7.35 %
  • 1 - 2 years: 17.65 %
  • 2 - 5 years: 23.53 %
  • 5 - 10 years: 13.24 %
  • 10+ years: 11.76 %

Gender of people who have Kidney Failure when taking Metformin *:

  • female: 47.14 %
  • male: 52.86 %

Age of people who have Kidney Failure when taking Metformin *:

  • 0-1: 0.12 %
  • 2-9: 0.0 %
  • 10-19: 0.12 %
  • 20-29: 1.59 %
  • 30-39: 4.41 %
  • 40-49: 9.91 %
  • 50-59: 20.07 %
  • 60+: 63.77 %

Severity if Kidney Failure when taking Metformin **:

  • least: 0.0 %
  • moderate: 0.0 %
  • severe: 100 %
  • most severe: 0.0 %

How people recovered from Kidney Failure **:

  • while on drug: 100 %
  • after off the drug: 0.0 %
  • not yet: 0.0 %

Top conditions involved for these people *:

  • Type 2 Diabetes Mellitus (231 people, 22.32%)
  • Diabetes Mellitus (224 people, 21.64%)
  • Hypertension (146 people, 14.11%)
  • Pain (48 people, 4.64%)
  • Atrial Fibrillation (46 people, 4.44%)

Top co-used drugs for these people *:

  • Lasix (113 people, 10.92%)
  • Aspirin (110 people, 10.63%)
  • Lisinopril (99 people, 9.57%)
  • Lantus (91 people, 8.79%)
  • Januvia (79 people, 7.63%)

Top other side effects for these people *:

  • Lactic Acidosis (144 people, 13.91%)
  • Dehydration (122 people, 11.79%)
  • Vomiting (116 people, 11.21%)
  • Diarrhoea (113 people, 10.92%)
  • Nausea (106 people, 10.24%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Kidney failure when taking Metformin?

Browse all side effects of Metformin

a b c d e f g h i j k l m n o p q r s t u v w x y z

Drugs that are associated with Kidney failure

Kidney failure

Could your condition cause Kidney failure

Kidney failure

Related studies

Can you answer these questions?

More questions for: Metformin, Kidney failure

You may be interested in these reviews

More reviews for: Metformin, Kidney failure


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.