Metformin and Kidney failure - from FDA reports


Summary

Kidney failure is found among people who take Metformin, especially for people who are male, 60+ old , have been taking the drug for 2 - 5 years, also take medication Aspirin, and have Type 2 diabetes. This review analyzes which people have Kidney failure with Metformin. It is created by eHealthMe based on reports of 191,114 people who have side effects when taking Metformin from FDA, and is updated regularly.

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On May, 15, 2017

191,114 people reported to have side effects when taking Metformin.
Among them, 3,129 people (1.64%) have Kidney Failure


Number of reports submitted per year:

Could Metformin cause Kidney failure?

Time on Metformin when people have Kidney Failure *:

  • < 1 month: 11.33 %
  • 1 - 6 months: 19.7 %
  • 6 - 12 months: 11.82 %
  • 1 - 2 years: 15.76 %
  • 2 - 5 years: 22.66 %
  • 5 - 10 years: 6.4 %
  • 10+ years: 12.32 %

Gender of people who have Kidney Failure when taking Metformin *:

  • female: 47.85 %
  • male: 52.15 %

Age of people who have Kidney Failure when taking Metformin *:

  • 0-1: 0.12 %
  • 2-9: 0.08 %
  • 10-19: 0.28 %
  • 20-29: 1.11 %
  • 30-39: 2.98 %
  • 40-49: 9.18 %
  • 50-59: 20.66 %
  • 60+: 65.55 %

Top conditions involved for these people *:

  • Type 2 Diabetes (722 people, 23.07%)
  • Diabetes (666 people, 21.28%)
  • High Blood Pressure (434 people, 13.87%)
  • High Blood Cholesterol (160 people, 5.11%)
  • Coronary Artery Bypass (133 people, 4.25%)

Top co-used drugs for these people *:

  • Aspirin (391 people, 12.50%)
  • Lisinopril (352 people, 11.25%)
  • Lasix (329 people, 10.51%)
  • Simvastatin (255 people, 8.15%)
  • Furosemide (253 people, 8.09%)

Top other side effects for these people *:

  • Lactic Acidosis (577 people, 18.44%)
  • Nausea And Vomiting (366 people, 11.70%)
  • Diarrhea (345 people, 11.03%)
  • Hypotension (327 people, 10.45%)
  • Dehydration (324 people, 10.35%)

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Kidney failure when taking Metformin?

Metformin

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin 198,499 users)

Kidney Failure

Kidney failure (loss of kidney function) has been reported by people with high blood pressure, multiple myeloma, coronary artery bypass, diabetes, rheumatoid arthritis (latest reports from 85,558 Kidney failure patients).

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Could your condition cause Kidney failure

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What would happen?

Forecast new side effects and undetected conditions when you take Metformin and have Kidney failure.

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