Review: could Metformin cause Kidney failure?
We study 97,185 people who have side effects while taking Metformin from FDA and social media. Among them, 1,904 have Kidney failure. Find out below who they are, when they have Kidney failure and more.
Stay connected: join a mobile support group for people who take Metformin and have Kidney failure >>>
Metformin (latest outcomes from 100,671 users) has active ingredients of metformin hydrochloride. It is often used in type 2 diabetes.
Kidney failure (loss of kidney function) (latest reports from 432,188 patients) has been reported by people with high blood pressure, coronary artery bypass, diabetes, multiple myeloma, high blood cholesterol.
On Jul, 18, 2014: 97,167 people reported to have side effects when taking Metformin. Among them, 1,904 people (1.96%) have Kidney Failure. They amount to 0.44% of all the 434,521 people who have Kidney Failure on eHealthMe.
Time on Metformin when people have Kidney failure * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Kidney failure||10.62%||25.66%||8.85%||14.16%||26.55%||2.65%||11.50% |
Gender of people who have Kidney failure when taking Metformin * :
|Kidney failure||47.37%||52.63% |
Age of people who have Kidney failure when taking Metformin * :
|Kidney failure||0.12%||0.06%||0.36%||0.30%||2.10%||9.70%||20.96%||66.41% |
Severity of Kidney failure when taking Metformin ** :
|least||moderate||severe||most severe |
|Kidney failure||0.00%||33.33%||66.67%||0.00% |
How people recovered from Kidney failure ** :
|while on the drug||after off the drug||not yet |
|Kidney failure||100.00%||0.00%||0.00% |
Top conditions involved for these people * :
- Diabetes mellitus (373 people, 19.59%)
- Type 2 diabetes mellitus (343 people, 18.01%)
- Hypertension (261 people, 13.71%)
- Depression (77 people, 4.04%)
- Diabetes mellitus non-insulin-dependent (77 people, 4.04%)
Top co-used drugs for these people * :
- Metformin hcl (1,333 people, 70.01%)
- Aspirin (439 people, 23.06%)
- Lisinopril (327 people, 17.17%)
- Lasix (270 people, 14.18%)
- Furosemide (239 people, 12.55%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
You can also:
Comments from related studies:
From this study (1 year ago):
Marie L on Jun, 20, 2012:
I am a 54-year-old Caucasian woman who recently underwent removal of a benign brain tumor via general anesthetic. Although I advised the anesthesia staff that I had been taking lithium for about 30 years, at the time of my surgery, I didn't know that lithium should be discontinued at least 72 hours to two weeks before surgery to avoid dehydration and resulting diabetes insipidis (abnormal urination)which is known to cause blindness. After my surgery, I was unable to be awakened and went into a "metabolic encephalopathy" for about three weeks. When I woke up, I was blind in my right eye. According to my neurosurgeon, the reason for the coma was due to lithium being in my system. As a result, I have total, irreversible blindness in my right eye. My surgeon's position is that it was not from the surgery and, instead, the medical staff had to wait until the lithium was flushed out of my body. This NEVER should have happened. My sodium levels sky-rocketed along with my blood pressure and blood sugar. If I would have known all of this before surgery, I would not have taken my lithium for the prescribed amount of time and definitely would have advised the doctor and medical staff accordingly. If you are taking lithium and have a general anesthesia scheduled, be sure to advise your surgeon and the anesthesia staff that you want to discontinue lithium until after the surgery when your vital signs are stable. Good luck to you.
LOA/13 on Mar, 27, 2013:
Hi Marie L,
I am also a female 57yrs, and have been trying to manage my Bipolar since my very early years. I like you, had surgery and because it was emergency surgery, no one had my medical records. At that time I was taking Lithium, the outcome was sever infection which took over 8mos to counteract. I appreciate your candor with your disclosure, because up until now (15 years later) I was only told the infection was due to the nature of the surgery (being emergency). Which I concluded, it was my fault for the outcome. I always thought the surgeons simplistic reasoning for the infection was a means by which to not have to fully disclaim the actual Reason = Lithium in my blood stream. I required another surgery for a broken arm (six places), which was postpone for several weeks. Now it makes sence for the postponement, he wanted to make sure the Lithium was out of my blood prior. This other surgery went off without a hitch. When and were possible, I highly recommend people to wear Medic Alert Bracelets, listing the medications you are taking. Thanks for listening.
LOA/13 on Mar, 27, 2013:
Female, 57yrs, Bipolar, looking for any comments with reference to interation of the following daily dosage drugs and the introduction of Lamotrigine to my dialy regiment.
Seroquel 800mg, Metforin 2000mg, Vimovo 500/40mg, Tylenol 2000mg. My Doc now would like to introduce Lamotrigine as a counter measure to my mood swings.
Does anyone have comments of the interation of these 4 drugs with Lamotrigine?
Your current and introductional experiences of this drug is appreciated. Thanks
Can you answer these questions (what is this?):
- Could any of the following drugs cause bullous pemphigoid
I have not developed blisters, just hives. I have been tested for most common allergies and appear not to have allergies. I have seen some descriptions on line and with drugs that seem t indicate a relation between these drugs and Bullous pemphigoid, but I have not been able to find more than a lin ...
- Creatinine rising on crestor & causing kidney failure
Husband been on Crestor for 3 years...Creatinine been increasing and he already is a diabetic and been watching his kidney function. Everything I read online points to the Crestor causing Kidney Failure but the doctors REFUSE to listen too us and now he is heading toward dialysis or a Kidney Transpl ...
- Can testosterone cause hyperkinectic heart symtom
I used testosone injections for more that 20 years.
More questions for: Metformin, Kidney failure
You may be interested at these reviews (what is this?):
- Olfactory issues due to metformin use
I've found that the metformin does not smell especially bad, but when I first started taking it, I could smell something horrible - to the point where I pulled apart my cupboards and fridge, fully expecting to find some maggot-riddled rotting meat. Eventually I realized I was smelling normal smel ...
- Metformin changes in mentrual cycle
At age 55, I started to enter menopause. When it began to taper off a couple of years ago, only one ovary was functioning, and my periods lasted only 1-2 days with minimal flow. Hadn't had a period in 4 months. Still had some PMS symptoms, but no flow. Was prescribed Metformin for pre-diabetes. My ...
- Metformin induced psoriatiform drug eruption
I'm a medical professional and I found psoratiform drug eruptions on my glans penis after taking metformin. This is the second time it has come and made me investigate the scenario myself. Lesions are scaly erythematous lesions and I am currently using low potency topical steroids after discontinuin ...
More reviews for: Metformin, Kidney failure
On eHealthMe, Metformin (metformin hydrochloride) is often used for diabetes. Find out below the conditions Metformin is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.
What is Metformin used for and how effective is it:
Other drugs that are used to treat the same conditions:
Could it be a symptom from a condition:
Drugs in real world that are associated with:
Could your condition cause it?
NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.