eHealthMe - Personalized health information & community eHealthMe - Personalized health information & community

Personalized health information & community

All drugs: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
All conditions: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Check symptoms   -   Check drugs   -   Compare drugs   -   Join a support group   -   More tools

Review: could Metformin cause Kidney failure (Acute kidney failure)?

Summary: Kidney failure is found among people who take Metformin, especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years, also take medication Metformin hcl, and have Diabetes.

We study 97,507 people who have side effects while taking Metformin from FDA and social media. Among them, 1,904 have Kidney failure. Find out below who they are, when they have Kidney failure and more.

You are not alone: join a support group for people who take Metformin and have Kidney failure >>>



Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from 101,041 Metformin users)

Kidney failure

Kidney failure (loss of kidney function) has been reported by people with high blood pressure, coronary artery bypass, diabetes, multiple myeloma, high blood cholesterol. (latest reports from 57,661 Kidney failure patients)

On Apr, 26, 2015: 97,507 people reported to have side effects when taking Metformin. Among them, 1,904 people (1.95%) have Kidney Failure.

Trend of Kidney failure in Metformin reports

Time on Metformin when people have Kidney failure * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Kidney failure10.62%25.66%8.85%14.16%26.55%2.65%11.50%

Gender of people who have Kidney failure when taking Metformin * :

Kidney failure47.37%52.63%

Age of people who have Kidney failure when taking Metformin * :

Kidney failure0.12%0.06%0.36%0.30%2.10%9.70%20.96%66.41%

Severity of Kidney failure when taking Metformin ** :

leastmoderateseveremost severe
Kidney failure0.00%33.33%66.67%0.00%

How people recovered from Kidney failure ** :

while on the drugafter off the drugnot yet
Kidney failure100.00%0.00%0.00%

Top conditions involved for these people * :

  1. Diabetes mellitus (373 people, 19.59%)
  2. Type 2 diabetes mellitus (343 people, 18.01%)
  3. Hypertension (261 people, 13.71%)
  4. Depression (77 people, 4.04%)
  5. Diabetes mellitus non-insulin-dependent (77 people, 4.04%)

Top co-used drugs for these people * :

  1. Metformin hcl (1,333 people, 70.01%)
  2. Aspirin (439 people, 23.06%)
  3. Lisinopril (327 people, 17.17%)
  4. Lasix (270 people, 14.18%)
  5. Furosemide (239 people, 12.55%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Kidney Failure while taking Metformin?




You are not alone! Join a support group on :
- support group for people who take Metformin and have Kidney Failure
- support group for people who take Metformin
- support group for people who have Kidney Failure

Drugs in real world that are associated with:

Could your condition cause:

Recent related drug studies (Check your drugs):

Recent Metformin related drug comparison:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


About - Terms of service - Privacy policy - Press - Testimonials - Contact us -

© 2015 All rights reserved. Use of this site constitutes acceptance of's terms of service and privacy policy.