Review: could Metformin cause Muscle Atrophy?


Summary

Muscle atrophy is found among people who take Metformin, especially for people who are male, 60+ old , have been taking the drug for 2 - 5 years, also take medication Simvastatin, and have Diabetes mellitus . We study 41,587 people who have side effects while taking Metformin from FDA and social media. Among them, 59 have Muscle atrophy. Find out below who they are, when they have Muscle atrophy and more.

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Metformin

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin 117,555 users)

Muscle Atrophy

Muscle atrophy (a decrease in the mass of the muscle) has been reported by people with nephrogenic systemic fibrosis, pain, gait disturbance, weakness, tendon disorder (latest reports from 6,173 Muscle atrophy patients).

On Aug, 24, 2016

41,587 people reported to have side effects when taking Metformin.
Among them, 59 people (0.14%) have Muscle Atrophy


Number of reports submitted per year:

Could Metformin cause Muscle atrophy?

Time on Metformin when people have Muscle Atrophy *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Muscle Atrophy when taking Metformin *:

  • female: 41.38 %
  • male: 58.62 %

Age of people who have Muscle Atrophy when taking Metformin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 1.85 %
  • 30-39: 1.85 %
  • 40-49: 1.85 %
  • 50-59: 31.48 %
  • 60+: 62.96 %

Severity if Muscle Atrophy when taking Metformin **:

  • least: 0.0 %
  • moderate: 0.0 %
  • severe: 100 %
  • most severe: 0.0 %

How people recovered from Muscle Atrophy **:

  • while on drug: 0.0 %
  • after off the drug: 0.0 %
  • not yet: 100 %

Top conditions involved for these people *:

  • Diabetes Mellitus (10 people)
  • Hypercholesterolaemia (9 people)
  • Blood Cholesterol Increased (9 people)
  • Gastrointestinal Disorder (8 people)
  • Arthralgia (8 people)

Top co-used drugs for these people *:

  • Simvastatin (14 people)
  • Aspirin (13 people)
  • Zometa (10 people)
  • Metoclopramide (10 people)
  • Insulin Glargine (10 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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