Review: could Metformin cause Muscle atrophy?
Summary: Muscle atrophy is found among people who take Metformin, especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years, also take medication Metformin hcl, and have High blood cholesterol.
We study 97,464 people who have side effects while taking Metformin from FDA and social media. Among them, 115 have Muscle atrophy. Find out below who they are, when they have Muscle atrophy and more.
You are not alone: join a mobile support group for people who take Metformin and have Muscle atrophy >>>
Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from 101,000 Metformin users)
Muscle atrophy (a decrease in the mass of the muscle) has been reported by people with high blood cholesterol, multiple sclerosis, high blood pressure, osteoporosis, pain. (latest reports from 5,638 Muscle atrophy patients)
On Feb, 27, 2015: 97,464 people reported to have side effects when taking Metformin. Among them, 115 people (0.12%) have Muscle Atrophy.
Time on Metformin when people have Muscle atrophy * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Muscle atrophy||20.00%||0.00%||0.00%||0.00%||60.00%||20.00%||0.00% |
Gender of people who have Muscle atrophy when taking Metformin * :
|Muscle atrophy||38.26%||61.74% |
Age of people who have Muscle atrophy when taking Metformin * :
|Muscle atrophy||0.00%||0.00%||0.00%||1.01%||5.05%||5.05%||25.25%||63.64% |
Severity of Muscle atrophy when taking Metformin ** :
|least||moderate||severe||most severe |
|Muscle atrophy||0.00%||66.67%||33.33%||0.00% |
How people recovered from Muscle atrophy ** :
|while on the drug||after off the drug||not yet |
|Muscle atrophy||0.00%||0.00%||100.00% |
Top conditions involved for these people * :
- Hypercholesterolaemia (17 people, 14.78%)
- Pain (11 people, 9.57%)
- Blood cholesterol increased (11 people, 9.57%)
- Type 2 diabetes mellitus (10 people, 8.70%)
- Neoplasm malignant (9 people, 7.83%)
Top co-used drugs for these people * :
- Metformin hcl (82 people, 71.30%)
- Lipitor (25 people, 21.74%)
- Actos (22 people, 19.13%)
- Aspirin (20 people, 17.39%)
- Glyburide (17 people, 14.78%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
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Do you have Muscle Atrophy while taking Metformin?
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Comments from related studies:
From this study (1 year ago):
I've lost 70 lbs in two years, 40 lbs. in the past year. I am having significant atrophy in my legs, specifically my right leg. As a 52 year old man, I cannot walk normally nor can I walk up stairs.
From this study (6 years ago):
Was never a smoker, but have intense cravings for cigarettes and seek to smoke 5-10 per day. Unusually/easily emotional. Highly agitated - take 5 or more walks per day to try to relieve the feeling. Significantly changed behavior and misses social cues, so may continue to repeat questions or opinions.
Behavioral and physical changes came on seemingly all at once, not gradually over time.
NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.
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