Metformin and Parkinson's disease - from FDA reports


Summary

Parkinson's disease is found among people who take Metformin, especially for people who are male, 60+ old , have been taking the drug for 2 - 5 years, also take medication Aspirin, and have Diabetes . We study 176,252 people who have side effects while taking Metformin from FDA. Among them, 212 have Parkinson's disease. Find out below who they are, when they have Parkinson's disease and more.

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Metformin

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin 183,363 users)

Parkinson's Disease

Parkinson's disease has been reported by people with parkinson's disease, depression, high blood pressure, osteoporosis, bipolar disorder (latest reports from 37,856 Parkinson's disease patients).

On Jan, 28, 2017

176,252 people reported to have side effects when taking Metformin.
Among them, 212 people (0.12%) have Parkinson's Disease


Number of reports submitted per year:

Could Metformin cause Parkinson's disease?

Time on Metformin when people have Parkinson's Disease *:

  • < 1 month: 15.38 %
  • 1 - 6 months: 7.69 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 69.23 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 7.69 %

Gender of people who have Parkinson's Disease when taking Metformin *:

  • female: 46.27 %
  • male: 53.73 %

Age of people who have Parkinson's Disease when taking Metformin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 7.83 %
  • 40-49: 5.42 %
  • 50-59: 8.43 %
  • 60+: 78.31 %

Top conditions involved for these people *:

  • Diabetes (60 people, 28.30%)
  • High Blood Pressure (39 people, 18.40%)
  • Type 2 Diabetes (35 people, 16.51%)
  • High Blood Cholesterol (22 people, 10.38%)
  • Depression (14 people, 6.60%)

Top co-used drugs for these people *:

  • Aspirin (38 people, 17.92%)
  • Simvastatin (27 people, 12.74%)
  • Lipitor (25 people, 11.79%)
  • Glipizide (25 people, 11.79%)
  • Seroquel (20 people, 9.43%)

Top other side effects for these people *:

  • Tremor (59 people, 27.83%)
  • Gait Disturbance (29 people, 13.68%)
  • Depression (29 people, 13.68%)
  • Weakness (28 people, 13.21%)
  • Fall (27 people, 12.74%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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