Review: could Metformin cause Parkinson's Disease?


Summary

Parkinson's disease is found among people who take Metformin, especially for people who are male, 60+ old , have been taking the drug for 2 - 5 years, also take medication Simvastatin, and have Diabetes mellitus . We study 84,420 people who have side effects while taking Metformin from FDA and social media. Among them, 120 have Parkinson's disease. Find out below who they are, when they have Parkinson's disease and more.

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Metformin

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin 174,670 users)

Parkinson's Disease

Parkinson's disease has been reported by people with pathological gambling, drug ineffective, confusional state, weakness, drowsiness (latest reports from 35,890 Parkinson's disease patients).

On Sep, 21, 2016

84,420 people reported to have side effects when taking Metformin.
Among them, 120 people (0.14%) have Parkinson's Disease


Number of reports submitted per year:

Could Metformin cause Parkinson's disease?

Time on Metformin when people have Parkinson's Disease *:

  • < 1 month: 7.14 %
  • 1 - 6 months: 7.14 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 14.29 %
  • 2 - 5 years: 64.29 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 7.14 %

Gender of people who have Parkinson's Disease when taking Metformin *:

  • female: 49.09 %
  • male: 50.91 %

Age of people who have Parkinson's Disease when taking Metformin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 12.09 %
  • 40-49: 5.49 %
  • 50-59: 5.49 %
  • 60+: 76.92 %

Severity if Parkinson's Disease when taking Metformin **:

  • least: 50 %
  • moderate: 50 %
  • severe: 0.0 %
  • most severe: 0.0 %

How people recovered from Parkinson's Disease **:

  • while on drug: 0.0 %
  • after off the drug: 0.0 %
  • not yet: 100 %

Top conditions involved for these people *:

  • Diabetes Mellitus (42 people, 35.00%)
  • Hypertension (23 people, 19.17%)
  • Type 2 Diabetes Mellitus (20 people, 16.67%)
  • Parkinson's Disease (17 people, 14.17%)
  • Blood Cholesterol (9 people, 7.50%)

Top co-used drugs for these people *:

  • Simvastatin (18 people, 15.00%)
  • Aspirin (14 people, 11.67%)
  • Lipitor (13 people, 10.83%)
  • Glipizide (12 people, 10.00%)
  • Metoclopramide (11 people, 9.17%)

Top other side effects for these people *:

  • Tremor (31 people, 25.83%)
  • Feeling Abnormal (15 people, 12.50%)
  • Balance Disorder (14 people, 11.67%)
  • Muscle Spasms (13 people, 10.83%)
  • Fatigue (13 people, 10.83%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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