Review: could Metformin cause Parkinson's Disease?


Summary

Parkinson's disease is found among people who take Metformin, especially for people who are male, 60+ old , have been taking the drug for 2 - 5 years, also take medication Simvastatin, and have Diabetes mellitus . We study 41,587 people who have side effects while taking Metformin from FDA and social media. Among them, 74 have Parkinson's disease. Find out below who they are, when they have Parkinson's disease and more.

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Metformin

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin 117,555 users)

Parkinson's Disease

Parkinson's disease has been reported by people with drug ineffective, pathological gambling, confusional state, drowsiness, depression (latest reports from 25,664 Parkinson's disease patients).

On Aug, 23, 2016

41,587 people reported to have side effects when taking Metformin.
Among them, 74 people (0.18%) have Parkinson's Disease


Number of reports submitted per year:

Could Metformin cause Parkinson's disease?

Time on Metformin when people have Parkinson's Disease *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 8.33 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 16.67 %
  • 2 - 5 years: 75.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Parkinson's Disease when taking Metformin *:

  • female: 48.44 %
  • male: 51.56 %

Age of people who have Parkinson's Disease when taking Metformin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 17.24 %
  • 40-49: 8.62 %
  • 50-59: 5.17 %
  • 60+: 68.97 %

Severity if Parkinson's Disease when taking Metformin **:

  • least: 50 %
  • moderate: 50 %
  • severe: 0.0 %
  • most severe: 0.0 %

How people recovered from Parkinson's Disease **:

  • while on drug: 0.0 %
  • after off the drug: 0.0 %
  • not yet: 100 %

Top conditions involved for these people *:

  • Diabetes Mellitus (32 people)
  • Hypertension (14 people)
  • Parkinson's Disease (10 people)
  • Blood Cholesterol (9 people)
  • Type 2 Diabetes Mellitus (7 people)

Top co-used drugs for these people *:

  • Simvastatin (18 people)
  • Aspirin (14 people)
  • Glipizide (12 people)
  • Metoclopramide (11 people)
  • Lipitor (10 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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