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Review: could Metformin cause Pre-eclampsia?

Summary: Pre-eclampsia is found among people who take Metformin, especially for people who are female, 30-39 old, have been taking the drug for 6 - 12 months, also take medication Metformin hcl, and have Type 2 diabetes.

We study 97,507 people who have side effects while taking Metformin from FDA and social media. Among them, 27 have Pre-eclampsia. Find out below who they are, when they have Pre-eclampsia and more.

You are not alone: join a support group for people who take Metformin and have Pre-eclampsia >>>



Metformin has active ingredients of metformin hydrochloride. It is often used in type 2 diabetes. (latest outcomes from 101,036 Metformin users)


Pre-eclampsia (high blood pressure and significant amounts of protein in the urine of a pregnant woman) has been reported by people with hiv infection, depression, birth control, high blood pressure, multiple sclerosis. (latest reports from 1,977 Pre-eclampsia patients)

On Apr, 3, 2015: 97,488 people reported to have side effects when taking Metformin. Among them, 27 people (0.03%) have Pre-eclampsia.

Trend of Pre-eclampsia in Metformin reports

Time on Metformin when people have Pre-eclampsia * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years

Gender of people who have Pre-eclampsia when taking Metformin * :


Age of people who have Pre-eclampsia when taking Metformin * :


Severity of Pre-eclampsia when taking Metformin ** :


How people recovered from Pre-eclampsia ** :


Top conditions involved for these people * :

  1. Type 2 diabetes mellitus (8 people, 29.63%)
  2. Pregnancy (4 people, 14.81%)
  3. Urinary tract infection (3 people, 11.11%)
  4. Polycystic ovaries (3 people, 11.11%)
  5. Amniotic cavity infection (2 people, 7.41%)

Top co-used drugs for these people * :

  1. Metformin hcl (16 people, 59.26%)
  2. Folic acid (6 people, 22.22%)
  3. Aspirin (4 people, 14.81%)
  4. Levothyroxine sodium (4 people, 14.81%)
  5. Atorvastatin (3 people, 11.11%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Pre-eclampsia while taking Metformin?




You are not alone! Join a support group on :
- support group for people who take Metformin and have Pre-eclampsia
- support group for people who take Metformin
- support group for people who have Pre-eclampsia

Drugs in real world that are associated with:

Could your condition cause:

Recent related drug studies (Check your drugs):

Recent Metformin related drug comparison:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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