Review: could Metformin cause Pre-eclampsia?


Summary

Pre-eclampsia is found among people who take Metformin, especially for people who are female, 30-39 old , have been taking the drug for 6 - 12 months, also take medication Folio, and have Depression . We study 84,420 people who have side effects while taking Metformin from FDA and social media. Among them, 16 have Pre-eclampsia. Find out below who they are, when they have Pre-eclampsia and more.

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Metformin

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin 174,668 users)

Pre-eclampsia

Pre-eclampsia (high blood pressure and significant amounts of protein in the urine of a pregnant woman) has been reported by people with serotonin syndrome, blood magnesium increased, failure to thrive, insomnia, drug exposure during pregnancy (latest reports from 2,969 Pre-eclampsia patients).

On Sep, 20, 2016

84,420 people reported to have side effects when taking Metformin.
Among them, 16 people (0.02%) have Pre-eclampsia


Number of reports submitted per year:

Could Metformin cause Pre-eclampsia?

Time on Metformin when people have Pre-eclampsia *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Pre-eclampsia when taking Metformin *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Pre-eclampsia when taking Metformin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 33.33 %
  • 30-39: 66.67 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

Top conditions involved for these people *:

  • Depression (5 people, 31.25%)
  • Insulin Resistance (3 people, 18.75%)
  • Hypothyroidism (3 people, 18.75%)
  • Glaucoma (3 people, 18.75%)
  • Polycystic Ovaries (2 people, 12.50%)

Top co-used drugs for these people *:

  • Latano Tim-Vision (3 people, 18.75%)
  • Folio (3 people, 18.75%)
  • L-Thyroxin (2 people, 12.50%)
  • Januvia (2 people, 12.50%)
  • Humalog (2 people, 12.50%)

Top other side effects for these people *:

  • Drug Exposure During Pregnancy (6 people, 37.50%)
  • Premature Labour (5 people, 31.25%)
  • Maternal Exposure During Pregnancy (4 people, 25.00%)
  • Premature Delivery (3 people, 18.75%)
  • Exposure During Pregnancy (3 people, 18.75%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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