Review: could Metformin cause Restless legs syndrome?
(By eHealthMe on Mar, 6, 2014)
Severity ratings: 2.7/4
On a scale of 1 to 4: 1=least, 2=moderate, 3=severe, 4=most severe
We study 91,513 people who take Metformin. Among them, 166 have Restless legs syndrome. See who they are, when they have Restless legs syndrome and more. This review is based on reports from FDA and social media, and is updated regularly.
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Metformin (latest outcomes from 100,457 users) has active ingredients of metformin hydrochloride. It is often used in diabetes, type 2 diabetes. Commonly reported side effects of Metformin include blood glucose increased, nausea, nausea aggravated, weight decreased, nausea and vomiting.
Restless legs syndrome
Restless legs syndrome (a powerful urge to move your legs) (latest reports from 65,992 patients) has been reported by people with restless leg syndrome, osteoporosis, depression, high blood pressure, pain.
On Mar, 6, 2014: 91,513 people reported to have side effects when taking Metformin. Among them, 166 people (0.18%) have Restless Legs Syndrome.
Time on Metformin when people have Restless legs syndrome * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Restless legs syndrome||0.00%||0.00%||22.22%||33.33%||0.00%||33.33%||11.11% |
Gender of people who have Restless legs syndrome when taking Metformin * :
|Restless legs syndrome||53.57%||46.43% |
Age of people who have Restless legs syndrome when taking Metformin * :
|Restless legs syndrome||0.00%||0.00%||0.00%||0.73%||8.76%||15.33%||29.20%||45.99% |
Severity of Restless legs syndrome when taking Metformin ** :
|least||moderate||severe||most severe |
|Restless legs syndrome||11.11%||33.33%||33.33%||22.22% |
How people recovered from Restless legs syndrome ** :
|while on the drug||after off the drug||not yet |
|Restless legs syndrome||0.00%||83.33%||16.67% |
Top conditions involved for these people * :
- Restless legs syndrome (30 people, 18.07%)
- Diabetes mellitus (30 people, 18.07%)
- Gastrooesophageal reflux disease (20 people, 12.05%)
- Hypertension (18 people, 10.84%)
- Depression (17 people, 10.24%)
Top co-used drugs for these people * :
- Metformin hcl (97 people, 58.43%)
- Aspirin (58 people, 34.94%)
- Lisinopril (50 people, 30.12%)
- Lipitor (41 people, 24.70%)
- Requip (34 people, 20.48%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
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Related topic: Metformin, Restless legs syndrome
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On eHealthMe, Metformin (metformin hydrochloride) is often used for diabetes. Find out below the conditions Metformin is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.
What is Metformin used for and how effective is it:
Other drugs that are used to treat the same conditions:
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Comments from related studies:
From this study (2 weeks ago):
Have been on Gabapentin for years now. For the past 3-4 yrs, I have had a chronically elevated WBC without evidence of illness. WBCs run 10.5 to 13.0 consistently. Even when on antibiotics, has not dropped below 10.5. Am now wondering if this could be related to Gabapentin. The elevated WBCs have resulted in delay of care for back pain issues. At one time, I tried to get off of gabapentin - was titrating the dose(c my provider's permission). I noticed that the Restless Leg Syndrome that I had been experiencing had disappeared with the lower dose of Gabapentin. Unfortunately, the Meralgia Paresthetica synotoms increased & had to increase the Gabapentin back up. RLS came back with increased dose.
From this study (2 weeks ago):
Have been on Gabapentin for years now. For the past 3-4 yrs, I have had a chronically elevated WBC without evidence of illness.WBCs run 10.5 tp 13.0 consistanly. Even when on antibiotics, has not dropped below 10.5. Am now wondering if this could be related to Gabapentin. The elevated WBCs have resulted in delay of care for back pain issues. At one time, I tried to get off of gabapentin - was titrating the dose(c my provider's permission). I noticed that the Restless Leg Syndrome that I had been experiencing had disappeared with the lower dose of Gabapentin. Unfortunately, the Meralgia Paresthetica synotoms increase & had to increase the Gabapentin back up. RLS came back with increased dose.
From this study (9 months ago):
Hoorppat on Jun, 21, 2013:
Profound Gloomy could be enduring objective been a bunch of chipboards and wires but they made it look fantastic.
It looked blood-curdling and electrifying - like something out of 2001, a humongous, raven, supercool hard compel
Abstruse Dismal could have well-grounded been a group of chipboards and wires but they made it look fantastic.
It looked spine-chilling and exciting - like something missing of 2001, a monstrous, negro, supercool severe pilot
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