Metformin and Secondary hypothyroidism - from FDA reports


Secondary hypothyroidism is reported only by a few people who take Metformin. We study 191,114 people who have side effects while taking Metformin from FDA. Among them, 5 have Secondary hypothyroidism. Find out below who they are, when they have Secondary hypothyroidism and more.

What to expect?

If you take Metformin and have Secondary hypothyroidism, find out what symptoms you could have in 1 year or longer.

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On May, 11, 2017

191,114 people reported to have side effects when taking Metformin.
Among them, 5 people (0.0%) have Secondary Hypothyroidism

Number of reports submitted per year:

Could Metformin cause Secondary hypothyroidism?

Gender of people who have Secondary Hypothyroidism when taking Metformin *:

  • female: 40 %
  • male: 60 %

Age of people who have Secondary Hypothyroidism when taking Metformin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 75 %
  • 50-59: 25 %
  • 60+: 0.0 %

Top conditions involved for these people *:

  • Nausea (2 people, 40.00%)
  • Type 2 Diabetes (1 person, 20.00%)
  • Pain (1 person, 20.00%)
  • Hormone Replacement Therapy (1 person, 20.00%)
  • Abdominal Discomfort (1 person, 20.00%)

Top co-used drugs for these people *:

  • Zyrtec (4 people, 80.00%)
  • Valium (4 people, 80.00%)
  • Byetta (4 people, 80.00%)
  • Kadian (3 people, 60.00%)
  • Gemfibrozil (3 people, 60.00%)

Top other side effects for these people *:

  • Tachypnea (3 people, 60.00%)
  • Multi-Organ Failure (3 people, 60.00%)
  • Heart Attack (3 people, 60.00%)
  • Drowsiness (3 people, 60.00%)
  • Diabetes Insipidus (3 people, 60.00%)

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Secondary hypothyroidism when taking Metformin?


Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin 198,499 users)

Secondary Hypothyroidism

Secondary hypothyroidism (pituitary gland and its failure to secrete tsh) has been reported by people with osteoporosis, pain, rheumatoid arthritis, muscle spasms, nausea (latest reports from 294 Secondary hypothyroidism patients).

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Drugs that are associated with Secondary hypothyroidism

Secondary hypothyroidism

Could your condition cause Secondary hypothyroidism

Secondary hypothyroidism

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What would happen?

Forecast new side effects and undetected conditions when you take Metformin and have Secondary hypothyroidism.

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