Review: could Metformin cause Systemic Lupus Erythematosus?


Summary

Systemic lupus erythematosus is found among people who take Metformin, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Plaquenil, and have Diabetes mellitus . We study 84,420 people who have side effects while taking Metformin from FDA and social media. Among them, 53 have Systemic lupus erythematosus. Find out below who they are, when they have Systemic lupus erythematosus and more.

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Metformin

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin 174,670 users)

Systemic Lupus Erythematosus

Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue) has been reported by people with breathing difficulty, fever, rashes, diarrhea, joint pain (latest reports from 22,170 Systemic lupus erythematosus patients).

On Sep, 16, 2016

84,420 people reported to have side effects when taking Metformin.
Among them, 53 people (0.06%) have Systemic Lupus Erythematosus


Number of reports submitted per year:

Could Metformin cause Systemic lupus erythematosus?

Time on Metformin when people have Systemic Lupus Erythematosus *:

  • < 1 month: 33.33 %
  • 1 - 6 months: 33.33 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 33.33 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Systemic Lupus Erythematosus when taking Metformin *:

  • female: 78.85 %
  • male: 21.15 %

Age of people who have Systemic Lupus Erythematosus when taking Metformin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 7.69 %
  • 20-29: 2.56 %
  • 30-39: 25.64 %
  • 40-49: 12.82 %
  • 50-59: 25.64 %
  • 60+: 25.64 %

Severity if Systemic Lupus Erythematosus when taking Metformin **:

  • least: 0.0 %
  • moderate: 0.0 %
  • severe: 0.0 %
  • most severe: 100 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (10 people, 18.87%)
  • Diabetes Mellitus (10 people, 18.87%)
  • Pain (9 people, 16.98%)
  • Gastrooesophageal Reflux Disease (9 people, 16.98%)
  • Systemic Lupus Erythematosus (8 people, 15.09%)

Top co-used drugs for these people *:

  • Plaquenil (12 people, 22.64%)
  • Nexium (10 people, 18.87%)
  • Prednisone. (8 people, 15.09%)
  • Methotrexate (8 people, 15.09%)
  • Lipitor (7 people, 13.21%)

Top other side effects for these people *:

  • Drug Ineffective (11 people, 20.75%)
  • Pain (10 people, 18.87%)
  • Gastrooesophageal Reflux Disease (10 people, 18.87%)
  • Nausea (8 people, 15.09%)
  • Diabetes Mellitus (8 people, 15.09%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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