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Review: could Metformin cause Vitamin d deficiency?

Summary: Vitamin d deficiency could be caused by Metformin, especially for people who are female, 60+ old, also take Metformin hcl, and have Diabetes mellitus.

We study 97,041 people who have side effects while taking Metformin from FDA and social media. Among them, 80 have Vitamin d deficiency. Find out below who they are, when they have Vitamin d deficiency and more.

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Metformin

Metformin (latest outcomes from 100,539 users) has active ingredients of metformin hydrochloride. It is often used in diabetes, type 2 diabetes. Commonly reported side effects of Metformin include blood glucose increased, nausea aggravated, nausea, weight decreased, diarrhea.

Vitamin d deficiency

Vitamin d deficiency (softening of bones) (latest reports from 31,311 patients) has been reported by people with osteoporosis, osteopenia, high blood pressure, gastrooesophageal reflux disease, multiple sclerosis.

On Apr, 11, 2014: 97,158 people reported to have side effects when taking Metformin. Among them, 80 people (0.08%) have Vitamin D Deficiency. They amount to 0.26% of all the 31,174 people who have Vitamin D Deficiency on eHealthMe.

Trend of Vitamin d deficiency in Metformin reports

Time on Metformin when people have Vitamin d deficiency * :

n/a

Gender of people who have Vitamin d deficiency when taking Metformin * :

FemaleMale
Vitamin d deficiency70.67%29.33%

Age of people who have Vitamin d deficiency when taking Metformin * :

0-12-910-1920-2930-3940-4950-5960+
Vitamin d deficiency0.00%0.00%0.00%0.00%4.35%17.39%27.54%50.72%

Severity of Vitamin d deficiency when taking Metformin ** :

leastmoderateseveremost severe
Vitamin d deficiency0.00%100.00%0.00%0.00%

How people recovered from Vitamin d deficiency ** :

n/a

Top conditions involved for these people * :

  1. Diabetes mellitus (30 people, 37.50%)
  2. Type 2 diabetes mellitus (13 people, 16.25%)
  3. Osteoporosis (11 people, 13.75%)
  4. Blood pressure (10 people, 12.50%)
  5. Gastrooesophageal reflux disease (9 people, 11.25%)

Top co-used drugs for these people * :

  1. Metformin hcl (38 people, 47.50%)
  2. Aspirin (29 people, 36.25%)
  3. Lisinopril (21 people, 26.25%)
  4. Vitamin d (15 people, 18.75%)
  5. Fosamax (14 people, 17.50%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Metformin, Vitamin d deficiency

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On eHealthMe, Metformin (metformin hydrochloride) is often used for diabetes. Find out below the conditions Metformin is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Metformin used for and how effective is it:

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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