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Review: could Methadone hydrochloride cause Rheumatoid arthritis?





Summary: Rheumatoid arthritis is found among people who take Methadone hydrochloride, especially for people who are female, 40-49 old, also take medication Zometa, and have Osteopenia.

We study 2,078 people who have side effects while taking Methadone hydrochloride from FDA and social media. Among them, 6 have Rheumatoid arthritis. Find out below who they are, when they have Rheumatoid arthritis and more.

You are not alone: join a mobile support group for people who take Methadone hydrochloride and have Rheumatoid arthritis >>>

Methadone hydrochloride

Methadone Hydrochloride has active ingredients of methadone hydrochloride. It is often used in pain. (latest outcomes from Methadone Hydrochloride 2,835 users)

Rheumatoid arthritis

Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints) has been reported by people with osteoporosis, high blood pressure, pain, high blood cholesterol, osteopenia.(latest reports from Rheumatoid arthritis 218,505 patients)

On Nov, 28, 2014: 2,073 people reported to have side effects when taking Methadone hydrochloride. Among them, 6 people (0.29%) have Rheumatoid Arthritis.

Trend of Rheumatoid arthritis in Methadone hydrochloride reports

Time on Methadone hydrochloride when people have Rheumatoid arthritis * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Rheumatoid arthritis0.00%0.00%0.00%50.00%0.00%0.00%50.00%

Age of people who have Rheumatoid arthritis when taking Methadone hydrochloride * :

0-12-910-1920-2930-3940-4950-5960+
Rheumatoid arthritis0.00%0.00%0.00%0.00%0.00%66.67%16.67%16.67%

Severity of Rheumatoid arthritis when taking Methadone hydrochloride ** :

leastmoderateseveremost severe
Rheumatoid arthritis0.00%100.00%0.00%0.00%

How people recovered from Rheumatoid arthritis ** :

while on the drugafter off the drugnot yet
Rheumatoid arthritis0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Osteopenia (2 people, 33.33%)
  2. Inflammation (2 people, 33.33%)
  3. Anxiety disorder (1 people, 16.67%)
  4. Constipation (1 people, 16.67%)
  5. Pain (1 people, 16.67%)

Top co-used drugs for these people * :

  1. Zometa (3 people, 50.00%)
  2. Zestril (3 people, 50.00%)
  3. Aspirin (3 people, 50.00%)
  4. Percocet (3 people, 50.00%)
  5. Protonix (3 people, 50.00%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Rheumatoid Arthritis while taking Methadone Hydrochloride?

You are not alone! Join a mobile support group:
- support group for people who take Methadone hydrochloride and have Rheumatoid Arthritis
- support group for people who take Methadone hydrochloride
- support group for people who have Rheumatoid Arthritis

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Can you answer these questions (Ask a question):

  • What side effects do you experience from sulpfasalazine? (3 answers)
    I began taking sulfasalazine 5 days ago for Rheumatoid arthritis. Since then I've had stomach cramps and bloating. Has anyone else experienced these side effects? If so, did the symptoms go away after using taking the meds for a while? And did the meds help the RA symptoms?
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  • Is there a support group in the us for people with insulinomas? (1 answer)
    SUPPORT GROUP IN UNITED STATES!!!

    Hi, the only support group that I've been able to find for people with insulinomas is located in the UK... just wondering if there is one in the US. I had pancreatic surgery to remove my first insulinoma in 2012, we're thinking there's another because I'm still having problems with hypoglycemia... if anyone know anything, PLEASE CONTACT ME!!! :)
    I know there can't just be a support group here for FERRETS!!! people are kind of important... I hate this song, but "Don't worry, BE HAPPY" is okay, I guess... I'm trying to force it upon myself. Things will get BETTER!!!
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  • Can long-term methadone use cause or increase the risk of colon cancer?
    I had a two-level spinal fusion at L4-S1 in 2000 after being injuried at work in Sept. 24, 1997. I lost everything after...the unjury, ability to do my job, my wife and family (couldn't take the strain) my home, my sense of self and purpose, direction and belonging...credit rating and ability to pay my bills.
    After a long period of waiting to settle my workmens' comp. case, I returned home, from the Bat Area back to Arizona to take of my mother with a yet un dianosed case of moderate dementia.
    Then, in 2011 I had a 2nd surgery to relieve spinal stenosis btwn. L2-L4, just above the fusion site.
    I've been taking methadone since early 2004, a little over ten years, now. I've had high blood pressure since my injury.

    Now, I waiting to be scheduled for a colonoscopy, with my father having had polyps and the way I've been feeling..drained, tired all the time, and stomach pains ( in addition to my chronic low back pain), I...
    find myself wondering if there is any relationtionship between the methadone and other meds and cancer?
    Reply
  • I am a 56 year old female with rheumatoid arthritis. i also have found out i have osteoporosis. i keep getting right breast sensitivity also tingling and tenderness in right scapula area... (2 answers)
    I am a 56 year old female with tingling in my right shoulder blade and some tenderness. I have occasional breast discomfort in the same side and sometimes my rt. nipple feels sensitive. If I touch the area, the symptom on the nipple vanishes. at times the tingling travels into my neck and symptoms seem more noticeable in the evening. If I shower in a warm shower the symptoms will vanish for a time.. All my mammograms have been normal and never miss any but it has me very worried. I check my breasts often for lumps. From time to time it also seems like I have tenderness along the sternum on that side. I have rhematoid arthritis as well as was recently told I have osteoporosis. I had a thoracic x-ray and they can see loss of bone density and some vertebrae degeneration. Take methotrexate each week and folic acid every day....Any ideas out there???? Thanks
    Reply
  • Do i need to temporarily stop taking my enbrel and methotrexate (that i take every week) while i am on azithromycin for severe cold symptoms? (1 answer)
    i have RA and take Enbrel and methotrexate every week. i am currently taking azithromycin, tussicaps and dexamethasone to treat a severe cold, cough, sore throat, etc. My question is should i stop taking the ra meds until my antibiotics and steroids are done? Or should i just continue as normal, don't want to get sicker than i already am!!!! thanks
    Reply

More questions for: Methadone hydrochloride, Rheumatoid arthritis

You may be interested at these reviews (Write a review):

  • 3 strong drugs together against neuropathic pain
    Neuropathic pain debuted when I was 24, now I'm 50. Received diagnosed with Ehler-Danlos syndrome (EDS), joint hypermobility type, when I was 35 years old. So it can take some time to get a diagnose. And as EDS-patient I do not belong to any clinic. Orthopedics says that EDS is not orthopedic, rheumatology says that EDS is not an autoimmune disease, GPs say that EDS is too difficult, and so on. Sooner or later we all end up at Psychiatry, even if we are not depressed.

    The first kind of pain I got when I was 24 came from low back, but I experienced as pelvic pain and leg pain. It was clearly a neuropathic pain, but it took years to find out. Later it was treated by a pain clinic with cortisone around the genitofemoral nerves (both sides). Since this treatment didn't result in lasting freedom from pain, the pain clinic started to give me RF (radio frequency) treatment. This made the pain disappeared after one year, and I was 80% free from it between 2002 and 2014, 12 years. The pain doctors said pain could return after 10 years.

    The other kind of neuropathic pain started 2003 with intense stomach pain. During 6 months I could hardly eat nothing due to nausea and vomiting. After this 6 months, stomach pain changed to almost unbearable pain in upper back.
    What happened 2003, and what all the doctors missed, was that the right lowest ribs slid up over the sternum. This rib dislocation is till there today, but now with a lot of cartilage formed around the rib where it is stuck in the lower end of the sternum. The dislocation is clearly visible on X-ray. This has greatly affected the thoracic spine. I have a scoliosis which I had not before 2003. And I still have severe pain in the thoracic spine.

    It was initially treated with morphine daily, and later with Durogesic (fentanyl), but this didn't help much. 2005 I was hospitalized because I had too much pain to take care of myself and my hygiene. After some months the doctors started to give me clonazepam because the muscles along the spine was in a chronic seizures. Clonazepam helped, but I could still have a lot of pain in two vertebrae in the thoracic spine. It felt as if someone drilled into the vertebrae without anesthesia. After a few months, doctors also prescribed me methadone. Then the pain disappeared almost completely. Since 2006, I have eaten clonazepam and methadone every day, and I need to sleep in an armchair to not get more pain because of moving during sleep.

    There are side effects. After 1,5 years with clonazepam and methadone I started to have panic attacks. Or rather one long panic attack which didn't stop before I got treatment with amitryptilin and pregabalin (Lyrica). These 2 medicines stopped the panic disorder completely after some hours, and the panic was then gone. Then I got side effects of these 2 medicines, amitryptilin & Lyrica, too. I gained a lot of weight (from 83 to 148 kg) and got much water (edema) in both my legs under the knees and in both feet. The feet could swallow to the double size. 2012 I stopped with amitryptilin and started to loose weight again (in Aug 2014 below 80 kg) and get less water in my legs. Today I eat as little medicines I can, but I have to take methadone, clonazepam and Lyrica every day, twice. If I try to take away one of these 3 medicines, I got pain problems at once. Lyrica is the most painful one to take away. In Sept-Dec 2013 I lowered Lyrica from 300 mg daily, to 150, then to 75 and finally 0 mg. The pain I had was extremely difficult to handle. It didn't help to take more methadone or anything else. I have checked on Internet and found that many people got pain from quitting with Lyrica. Most people start eating it again. So did I. But 2006 and 2007 it was enough to treat the pain with methadone and clonazepam, I got the Lyrica against anxiety not pain. But today I take Lyrica against pain.

    Beside weight gain and leg edema, clonazepam and Lyrica significantly affect the sexual desire. And Lyrica alone makes it almost impossible to ejaculate. All four drugs together (clonazepam, methadone, amitryptiline and Lyrica), make one forget all about sex life. You don't even miss it. When I stopped with amitryptiline and lowered Lyrica (still taking clonazepam and methadone), I could suddenly easily get erections again, feel desire, but not getting orgasms. This is quite difficult to deal with.

    The pain pattern is greatly affected, by pain and by the medicines. So is the mood. I get something which feels like heavy depression, especially if I take the medicines late that day. I should take a medicine like methadone 3 times a day, because the effects of the tablet lasts around 8 hours. But I take them every 12 hours, to have a low consumption in case doctors prescribe them too late (which happens, and then it's good to have a spouse going to the pharmacy buying them for you, because you have too much pain to go yourself).

    Since methadone is also used for treating heroine addicts, medical staff treat you with disrespect when they see that it says "methadone" in your health record. I need to show a certificate that says that I deal with chronic neuropathic pain, that I never have had problems with drug addiction, to get normal respect.

    I wanted to share this because I think I am alone in the world with these medicines in combination against neuropathic pain caused by hypermobile joints, joint dislocation and muscle spasms. After trying almost everything else, including surgery cutting nerves, methadone, clonazepam and Lyrica seems to be the only way to kill my pain. But it's a life where you always is questioned, because of the use of methadone. I can guarantee that everybody in the world should accept these medicines if they had experienced the unbearable pain I had in upper back before they started to give me clonazepam and methadone.
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  • Why has my bloodpresher now shot up
    My blood pressure was always low 120/68 now since being treated for rheumatoid arthritis it has shot up to 175/92
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    Started taking Nexium 1 week ago and I noticed improvement with my chronic constipation.
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  • Had nms in 2005, will trileptal increase chance of recurrence?
    In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrollable shivering) continued & got higher. By 5/05 my temps were reaching 105 deg F. Husband said I became combative, refused to go to hospital. Early June/05 he came home to find me wrapped in blankets, with a temp over 105 F. He tried to place me in a tub of cold water, said I was rigid & screamed when he tried to move me. I was in the tub, speaking "in tongues" (his description, I have no memory of this). He called 911, took me to hospital. I woke, no idea where I was or why. After a lumbar puncture & 2 days in ICU I went home. The fevers continued...2 weeks later he came home to find me wrapped in sheets, towels, blankets, with the heat on full (it was in the 90's outside) he called ambulance again. I awoke to find myself under an ice blanket with nurses pushing large vials of dantrolene into both arms, several liters. Another LP, a stint in ICU...this time they told me it was NMS. The dr who dxd me said he was surprised I was alive, & not a vegetable, as my temp had peaked at 109 deg F. I suffered brain damage; short-term memory loss, brain can't control my body temp, my blood pressure went up. An arteriogram showed completely healthy heart & arteries, no plaque at all. I lost all body fat as well as some muscle mass. The fevers continued even after stopping the Seroquel. I visited my PCP for a checkup in 9/05, temp was normal. I started shuddering, my temp went up a full degree every 5 minutes. PCP admitted me to ER, my heart rate was over 272 B/M; they stopped my heart 3 times to "reset" it, which didn't work. I spent 3 days in hospital. Several months later my P doc tried me on Lamictal alone; I got Stevens-Johnson syndrome. I stopped the drug as soon as the signs appeared. I've been untreated, except for Neurontin & Primidone, until my manic episodes became unlivable. 3 weeks ago I went 8 days with no sleep, became psychotic. My P doc gave me Trileptal, which has evened my moods, but I've been getting low-grade fevers (highest was 103.6). Would having had NMS in the past make me more prone to falling to it again with the Trileptal? It's the only new med I've taken in over a year.
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  • Sulfasalazine and the never ending menstrual cycle
    I started this drug and never had menstrual problems begore. Within 3 months, I started my period and it never stopped even with stopping the drug for 3 mon ths. I ended up going my gyne and he prescribed megace. I had been bleeding for a total of 6 months. Made an appt with my rhuemy and explained this situation. His words were "it hasn't been listed in the literature as a side effect". Keep taking it. I started it again. Same situation and same treatment. Never took it again and changed rheumy.
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More reviews for: Methadone hydrochloride, Rheumatoid arthritis

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