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Review: could Methadone hydrochloride cause Rheumatoid arthritis?

Summary: Rheumatoid arthritis is found among people who take Methadone hydrochloride, especially for people who are female, 40-49 old, also take medication Zometa, and have Osteopenia.

We study 2,080 people who have side effects while taking Methadone hydrochloride from FDA and social media. Among them, 6 have Rheumatoid arthritis. Find out below who they are, when they have Rheumatoid arthritis and more.

You are not alone: join a mobile support group for people who take Methadone hydrochloride and have Rheumatoid arthritis >>>

 

 

 

 

Methadone hydrochloride

Methadone hydrochloride has active ingredients of methadone hydrochloride. It is often used in pain. (latest outcomes from 2,842 Methadone hydrochloride users)

Rheumatoid arthritis

Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints) has been reported by people with osteoporosis, high blood pressure, pain, high blood cholesterol, osteopenia. (latest reports from 218,584 Rheumatoid arthritis patients)

On Jan, 28, 2015: 2,080 people reported to have side effects when taking Methadone hydrochloride. Among them, 6 people (0.29%) have Rheumatoid Arthritis.

Trend of Rheumatoid arthritis in Methadone hydrochloride reports

Time on Methadone hydrochloride when people have Rheumatoid arthritis * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Rheumatoid arthritis0.00%0.00%0.00%50.00%0.00%0.00%50.00%

Age of people who have Rheumatoid arthritis when taking Methadone hydrochloride * :

0-12-910-1920-2930-3940-4950-5960+
Rheumatoid arthritis0.00%0.00%0.00%0.00%0.00%66.67%16.67%16.67%

Severity of Rheumatoid arthritis when taking Methadone hydrochloride ** :

leastmoderateseveremost severe
Rheumatoid arthritis0.00%100.00%0.00%0.00%

How people recovered from Rheumatoid arthritis ** :

while on the drugafter off the drugnot yet
Rheumatoid arthritis0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Osteopenia (2 people, 33.33%)
  2. Inflammation (2 people, 33.33%)
  3. Anxiety disorder (1 people, 16.67%)
  4. Constipation (1 people, 16.67%)
  5. Pain (1 people, 16.67%)

Top co-used drugs for these people * :

  1. Zometa (3 people, 50.00%)
  2. Zestril (3 people, 50.00%)
  3. Aspirin (3 people, 50.00%)
  4. Percocet (3 people, 50.00%)
  5. Protonix (3 people, 50.00%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Rheumatoid Arthritis while taking Methadone Hydrochloride?

You are not alone! Join a mobile support group:
- support group for people who take Methadone hydrochloride and have Rheumatoid Arthritis
- support group for people who take Methadone hydrochloride
- support group for people who have Rheumatoid Arthritis

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More questions for: Methadone hydrochloride, Rheumatoid arthritis

You may be interested at these reviews (Write a review):

  • Methadone and forgetting basic things.
    I have been in MMT (Methadone Maintenance Treatment) for around 7 1/2 years for chronic pain. I have gotten to where I forget things that I never would or did before and the longer in time the worse it has gotten I am currently looking at some different meds for treatment. The loss of memory is everything from childhood memories to what I did yesterday I may pay something and if I dont write it diwn I will forget it things I have known all my life I have forgotten. I can't say 100% it is from the MMT or not however I will sag I had no such problems before and I am at age 38 so I believe I am much too young to have severe memory loss that I am currently experiencing and whats scary is what if it never comes back and continues to decline?
  • 3 strong drugs together against neuropathic pain
    Neuropathic pain debuted when I was 24, now I'm 50. Received diagnosed with Ehler-Danlos syndrome (EDS), joint hypermobility type, when I was 35 years old. So it can take some time to get a diagnose. And as EDS-patient I do not belong to any clinic. Orthopedics says that EDS is not orthopedic, rheumatology says that EDS is not an autoimmune disease, GPs say that EDS is too difficult, and so on. Sooner or later we all end up at Psychiatry, even if we are not depressed.

    The first kind of pain I got when I was 24 came from low back, but I experienced as pelvic pain and leg pain. It was clearly a neuropathic pain, but it took years to find out. Later it was treated by a pain clinic with cortisone around the genitofemoral nerves (both sides). Since this treatment didn't result in lasting freedom from pain, the pain clinic started to give me RF (radio frequency) treatment. This made the pain disappeared after one year, and I was 80% free from it between 2002 and 2014, 12 years. The pain doctors said pain could return after 10 years.

    The other kind of neuropathic pain started 2003 with intense stomach pain. During 6 months I could hardly eat nothing due to nausea and vomiting. After this 6 months, stomach pain changed to almost unbearable pain in upper back.
    What happened 2003, and what all the doctors missed, was that the right lowest ribs slid up over the sternum. This rib dislocation is till there today, but now with a lot of cartilage formed around the rib where it is stuck in the lower end of the sternum. The dislocation is clearly visible on X-ray. This has greatly affected the thoracic spine. I have a scoliosis which I had not before 2003. And I still have severe pain in the thoracic spine.

    It was initially treated with morphine daily, and later with Durogesic (fentanyl), but this didn't help much. 2005 I was hospitalized because I had too much pain to take care of myself and my hygiene. After some months the doctors started to give me clonazepam because the muscles along the spine was in a chronic seizures. Clonazepam helped, but I could still have a lot of pain in two vertebrae in the thoracic spine. It felt as if someone drilled into the vertebrae without anesthesia. After a few months, doctors also prescribed me methadone. Then the pain disappeared almost completely. Since 2006, I have eaten clonazepam and methadone every day, and I need to sleep in an armchair to not get more pain because of moving during sleep.

    There are side effects. After 1,5 years with clonazepam and methadone I started to have panic attacks. Or rather one long panic attack which didn't stop before I got treatment with amitryptilin and pregabalin (Lyrica). These 2 medicines stopped the panic disorder completely after some hours, and the panic was then gone. Then I got side effects of these 2 medicines, amitryptilin & Lyrica, too. I gained a lot of weight (from 83 to 148 kg) and got much water (edema) in both my legs under the knees and in both feet. The feet could swallow to the double size. 2012 I stopped with amitryptilin and started to loose weight again (in Aug 2014 below 80 kg) and get less water in my legs. Today I eat as little medicines I can, but I have to take methadone, clonazepam and Lyrica every day, twice. If I try to take away one of these 3 medicines, I got pain problems at once. Lyrica is the most painful one to take away. In Sept-Dec 2013 I lowered Lyrica from 300 mg daily, to 150, then to 75 and finally 0 mg. The pain I had was extremely difficult to handle. It didn't help to take more methadone or anything else. I have checked on Internet and found that many people got pain from quitting with Lyrica. Most people start eating it again. So did I. But 2006 and 2007 it was enough to treat the pain with methadone and clonazepam, I got the Lyrica against anxiety not pain. But today I take Lyrica against pain.

    Beside weight gain and leg edema, clonazepam and Lyrica significantly affect the sexual desire. And Lyrica alone makes it almost impossible to ejaculate. All four drugs together (clonazepam, methadone, amitryptiline and Lyrica), make one forget all about sex life. You don't even miss it. When I stopped with amitryptiline and lowered Lyrica (still taking clonazepam and methadone), I could suddenly easily get erections again, feel desire, but not getting orgasms. This is quite difficult to deal with.

    The pain pattern is greatly affected, by pain and by the medicines. So is the mood. I get something which feels like heavy depression, especially if I take the medicines late that day. I should take a medicine like methadone 3 times a day, because the effects of the tablet lasts around 8 hours. But I take them every 12 hours, to have a low consumption in case doctors prescribe them too late (which happens, and then it's good to have a spouse going to the pharmacy buying them for you, because you have too much pain to go yourself).

    Since methadone is also used for treating heroine addicts, medical staff treat you with disrespect when they see that it says "methadone" in your health record. I need to show a certificate that says that I deal with chronic neuropathic pain, that I never have had problems with drug addiction, to get normal respect.

    I wanted to share this because I think I am alone in the world with these medicines in combination against neuropathic pain caused by hypermobile joints, joint dislocation and muscle spasms. After trying almost everything else, including surgery cutting nerves, methadone, clonazepam and Lyrica seems to be the only way to kill my pain. But it's a life where you always is questioned, because of the use of methadone. I can guarantee that everybody in the world should accept these medicines if they had experienced the unbearable pain I had in upper back before they started to give me clonazepam and methadone.
  • Why has my bloodpresher now shot up
    My blood pressure was always low 120/68 now since being treated for rheumatoid arthritis it has shot up to 175/92
  • Nexium improves my constipation
    Started taking Nexium 1 week ago and I noticed improvement with my chronic constipation.
  • Had nms in 2005, will trileptal increase chance of recurrence?
    In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrollable shivering) continued & got higher. By 5/05 my temps were reaching 105 deg F. Husband said I became combative, refused to go to hospital. Early June/05 he came home to find me wrapped in blankets, with a temp over 105 F. He tried to place me in a tub of cold water, said I was rigid & screamed when he tried to move me. I was in the tub, speaking "in tongues" (his description, I have no memory of this). He called 911, took me to hospital. I woke, no idea where I was or why. After a lumbar puncture & 2 days in ICU I went home. The fevers continued...2 weeks later he came home to find me wrapped in sheets, towels, blankets, with the heat on full (it was in the 90's outside) he called ambulance again. I awoke to find myself under an ice blanket with nurses pushing large vials of dantrolene into both arms, several liters. Another LP, a stint in ICU...this time they told me it was NMS. The dr who dxd me said he was surprised I was alive, & not a vegetable, as my temp had peaked at 109 deg F. I suffered brain damage; short-term memory loss, brain can't control my body temp, my blood pressure went up. An arteriogram showed completely healthy heart & arteries, no plaque at all. I lost all body fat as well as some muscle mass. The fevers continued even after stopping the Seroquel. I visited my PCP for a checkup in 9/05, temp was normal. I started shuddering, my temp went up a full degree every 5 minutes. PCP admitted me to ER, my heart rate was over 272 B/M; they stopped my heart 3 times to "reset" it, which didn't work. I spent 3 days in hospital. Several months later my P doc tried me on Lamictal alone; I got Stevens-Johnson syndrome. I stopped the drug as soon as the signs appeared. I've been untreated, except for Neurontin & Primidone, until my manic episodes became unlivable. 3 weeks ago I went 8 days with no sleep, became psychotic. My P doc gave me Trileptal, which has evened my moods, but I've been getting low-grade fevers (highest was 103.6). Would having had NMS in the past make me more prone to falling to it again with the Trileptal? It's the only new med I've taken in over a year.

More reviews for: Methadone hydrochloride, Rheumatoid arthritis

Comments from related studies:

  • From this study (17 hours ago):

  • I take a lot of medications other than Methadone as follows:
    1.Remeron (30 mg daily)
    2. Elavil (100 mg daily)
    3. Trazadone (300 mg daily)
    4. Cymbalta (120 mg daily)
    5. gabapentin (1600 mg daily)
    6. vistaril (75 mg daily)
    7. Vytorin (10/40 mg)
    8. synthroid (100 mg.)

    Reply

  • From this study (1 month ago):

  • Rosacea appeared after a few months on Methadone.

    Reply

  • From this study (2 months ago):

  • I have pain on the left side of my chest below the rib cage, but I can't seem to find it though when I push on that area, but when I move or cough can feel it there. It comes and goes, but always seems to be there. I drink coffee, and have just started using a morning egg white protein mix by Jay Robb the last few weeks, along with an energy supplement. It seems to be more pronounced now, and I am contemplating seeing a doctor. I figured I had pulled stomach muscles on that side as I know that can also make this type of pain. Pushing on it doesn't locate the pain. I have had this more than a year, but since it comes and goes figured it was an ulcer.
    Could it be a simple ulcer brought on by years (12) of methadone use? I use between 10 to 15mG/day which isn't a lot but I did use more when the pain was worse. I had been using up to 30mg/day about three years ago and started using less as the pain seemed better. I had surgery for a ruptured C5/C6 disk (no fused disk) in 2001 and that never got rid of all of the pain in arm/hand and left side of neck, though it did take care of the pain in between my shoulders. I took oxycontin for the first few years up to 60mG/day, and then started methadone treatment as it was cheaper, and the results were as good.

    Reply

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