Review: could Methimazole cause Pruritus?


Pruritus is found among people who take Methimazole, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Zantac, and have Multiple myeloma . We study 1,730 people who have side effects while taking Methimazole from FDA and social media. Among them, 56 have Pruritus. Find out below who they are, when they have Pruritus and more.

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Methimazole has active ingredients of methimazole. It is often used in hyperthyroidism. (latest outcomes from Methimazole 1,924 users)


Pruritus (severe itching of the skin) has been reported by people with breathing difficulty, erythema multiforme, thrombocytopenia, feeling abnormal, diarrhea (latest reports from 109,065 Pruritus patients).

On Aug, 27, 2016

1,730 people reported to have side effects when taking Methimazole.
Among them, 56 people (3.24%) have Pruritus

Number of reports submitted per year:

Could Methimazole cause Pruritus?

Time on Methimazole when people have Pruritus *:

  • < 1 month: 62.5 %
  • 1 - 6 months: 25.0 %
  • 6 - 12 months: 12.5 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Pruritus when taking Methimazole *:

  • female: 91.07 %
  • male: 8.93 %

Age of people who have Pruritus when taking Methimazole *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 4.17 %
  • 20-29: 0.0 %
  • 30-39: 18.75 %
  • 40-49: 8.33 %
  • 50-59: 20.83 %
  • 60+: 47.92 %

Top conditions involved for these people *:

  • Multiple Myeloma (14 people)
  • Mastocytosis (12 people)
  • Hyperthyroidism (12 people)
  • Pain (6 people)
  • Blood Cholesterol Increased (5 people)

Top co-used drugs for these people *:

  • Zantac (18 people)
  • Valium (16 people)
  • Tapazole (15 people)
  • Percocet (14 people)
  • Gleevec (14 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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