Methotrexate sodium and Dementia - from FDA reports


Dementia is found among people who take Methotrexate sodium, especially for people who are female, 60+ old also take medication Enbrel, and have Rheumatoid arthritis. This review analyzes which people have Dementia with Methotrexate sodium. It is created by eHealthMe based on reports of 15,178 people who have side effects when taking Methotrexate sodium from FDA, and is updated regularly.

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On Apr, 25, 2017

15,178 people reported to have side effects when taking Methotrexate Sodium.
Among them, 19 people (0.13%) have Dementia

Number of reports submitted per year:

Could Methotrexate sodium cause Dementia?

Gender of people who have Dementia when taking Methotrexate Sodium *:

  • female: 57.89 %
  • male: 42.11 %

Age of people who have Dementia when taking Methotrexate Sodium *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 13.33 %
  • 60+: 86.67 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (16 people, 84.21%)
  • Burkitt's Lymphoma (2 people, 10.53%)
  • Hyperlipidaemia (1 person, 5.26%)
  • High Blood Pressure (1 person, 5.26%)
  • Depression (1 person, 5.26%)

Top co-used drugs for these people *:

  • Enbrel (9 people, 47.37%)
  • Lansoprazole (8 people, 42.11%)
  • Actonel (8 people, 42.11%)
  • Leucovorin Calcium (7 people, 36.84%)
  • Celebrex (7 people, 36.84%)

Top other side effects for these people *:

  • Weight Decreased (13 people, 68.42%)
  • Schizophrenia (8 people, 42.11%)
  • Persecutory Delusion (7 people, 36.84%)
  • Hallucination, Auditory (7 people, 36.84%)
  • Tuberculosis (4 people, 21.05%)

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Dementia when taking Methotrexate sodium?

Methotrexate Sodium

Methotrexate sodium has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate sodium 16,479 users)


Dementia (madness) has been reported by people with osteoporosis, high blood pressure, multiple sclerosis, depression, rheumatoid arthritis (latest reports from 19,499 Dementia patients).

Browse all side effects of Methotrexate sodium

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Drugs that are associated with Dementia


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What would happen?

Forecast new side effects and undetected conditions when you take Methotrexate sodium and have Dementia.

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