Review: could Methotrexate Sodium cause Fluid Retention?


Summary

Fluid retention is found among people who take Methotrexate Sodium, especially for people who are female, 20-29 old , have been taking the drug for 1 - 6 months, also take medication Enbrel, and have Rheumatoid arthritis . We study 7,031 people who have side effects while taking Methotrexate sodium from FDA and social media. Among them, 12 have Fluid retention. Find out below who they are, when they have Fluid retention and more.

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Methotrexate Sodium

Methotrexate sodium has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate sodium 7,518 users)

Fluid Retention

Fluid retention (an abnormal accumulation of fluid in the blood) has been reported by people with breathing difficulty, pain, weakness, diarrhea, high blood pressure (latest reports from 17,764 Fluid retention patients).

On Jul, 21, 2016

7,031 people reported to have side effects when taking Methotrexate Sodium.
Among them, 12 people (0.17%) have Fluid Retention


Number of reports submitted per year:

Could Methotrexate sodium cause Fluid retention?

Time on Methotrexate Sodium when people have Fluid Retention *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 66.67 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 33.33 %
  • 10+ years: 0.0 %

Gender of people who have Fluid Retention when taking Methotrexate Sodium *:

  • female: 66.67 %
  • male: 33.33 %

Age of people who have Fluid Retention when taking Methotrexate Sodium *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 33.33 %
  • 30-39: 11.11 %
  • 40-49: 11.11 %
  • 50-59: 22.22 %
  • 60+: 22.22 %

Severity if Fluid Retention when taking Methotrexate Sodium **:

  • least: 0.0 %
  • moderate: 100 %
  • severe: 0.0 %
  • most severe: 0.0 %

How people recovered from Fluid Retention **:

  • while on drug: 0.0 %
  • after off the drug: 0.0 %
  • not yet: 100 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (5 people)
  • Psoriasis (2 people)
  • Lymphocytic Leukaemia (1 person)
  • Clostridium Difficile Colitis (1 person)

Top co-used drugs for these people *:

  • Folic Acid (4 people)
  • Enbrel (4 people)
  • Prednisone (2 people)
  • Indomethacin (2 people)
  • Cyclophosphamide (2 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Fluid retention when taking Methotrexate sodium?

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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