Methotrexate sodium and Fluid retention - from FDA reports


Summary

Fluid retention is found among people who take Methotrexate Sodium, especially for people who are female, 60+ old , have been taking the drug for 1 - 6 months, also take medication Enbrel, and have Rheumatoid arthritis . We study 11,813 people who have side effects while taking Methotrexate sodium from FDA. Among them, 20 have Fluid retention. Find out below who they are, when they have Fluid retention and more.

What to expect?

If you take Methotrexate sodium and have Fluid retention, find out what symptoms you could have in 1 year or longer.

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Methotrexate Sodium

Methotrexate sodium has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate sodium 13,112 users)

Fluid Retention

Fluid retention (an abnormal accumulation of fluid in the blood) has been reported by people with primary pulmonary hypertension, pulmonary hypertension, high blood pressure, diabetes, multiple sclerosis (latest reports from 35,420 Fluid retention patients).

On Feb, 19, 2017

11,813 people reported to have side effects when taking Methotrexate Sodium.
Among them, 20 people (0.17%) have Fluid Retention


Number of reports submitted per year:

Could Methotrexate sodium cause Fluid retention?

Time on Methotrexate Sodium when people have Fluid Retention *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 66.67 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 33.33 %
  • 10+ years: 0.0 %

Gender of people who have Fluid Retention when taking Methotrexate Sodium *:

  • female: 70 %
  • male: 30 %

Age of people who have Fluid Retention when taking Methotrexate Sodium *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 7.14 %
  • 20-29: 14.29 %
  • 30-39: 7.14 %
  • 40-49: 14.29 %
  • 50-59: 14.29 %
  • 60+: 42.86 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (10 people, 50.00%)
  • Psoriasis (2 people, 10.00%)
  • Pain (2 people, 10.00%)
  • Multiple Sclerosis (1 person, 5.00%)
  • Fatigue (1 person, 5.00%)

Top co-used drugs for these people *:

  • Enbrel (8 people, 40.00%)
  • Folic Acid (5 people, 25.00%)
  • Plaquenil (3 people, 15.00%)
  • Orencia (3 people, 15.00%)
  • Vitamins (2 people, 10.00%)

Top other side effects for these people *:

  • Breathing Difficulty (5 people, 25.00%)
  • Weight Increased (4 people, 20.00%)
  • Pleural Effusion (4 people, 20.00%)
  • Joint Swelling (3 people, 15.00%)
  • Ascites (3 people, 15.00%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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