Review: could Methotrexate cause Constipation?
(By eHealthMe on Mar, 7, 2014)
Severity ratings: 3.0/4
On a scale of 1 to 4: 1=least, 2=moderate, 3=severe, 4=most severe
We study 6,472 people who take Methotrexate. Among them, 44 have Constipation. See who they are, when they have Constipation and more. This review is based on reports from FDA and social media, and is updated regularly.
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Methotrexate sodium (latest outcomes from 7,237 users) has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis, psoriatic arthritis. Commonly reported side effects of Methotrexate sodium include fever, pneumonia, nausea, joint pain, fatigue.
Constipation (latest reports from 493,583 patients) has been reported by people with pain, osteoporosis, high blood pressure, depression, high blood cholesterol.
On Feb, 13, 2014: 6,472 people reported to have side effects when taking Methotrexate sodium. Among them, 37 people (0.57%) have Constipation.
Time on Methotrexate sodium when people have Constipation * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
Age of people who have Constipation when taking Methotrexate sodium * :
Severity of Constipation when taking Methotrexate sodium ** :
|least||moderate||severe||most severe |
How people recovered from Constipation ** :
Top conditions involved for these people * :
- Rheumatoid arthritis (21 people, 56.76%)
- Pain (13 people, 35.14%)
- Osteoporosis (11 people, 29.73%)
- Pain management (8 people, 21.62%)
- Blood thyroid stimulating hormone decreased (8 people, 21.62%)
Top co-used drugs for these people * :
- Prednisone (23 people, 62.16%)
- Folic acid (18 people, 48.65%)
- Remicade (15 people, 40.54%)
- Levothyroxine sodium (14 people, 37.84%)
- Humira (13 people, 35.14%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Related topic: Methotrexate sodium, Constipation
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On eHealthMe, Methotrexate Sodium (methotrexate sodium) is often used for rheumatoid arthritis. Find out below the conditions Methotrexate Sodium is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.
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Comments from related studies:
From this study (5 months ago):
I suffer from UC for 8 years, the past 2 years I have had many flare ups, so I am almost Steroid dependent, as they are the only thing that works. So to get off Steroids, i have tried Azathiopran (didn't work caused severe side-effects) then 6MP, (also failed due to lowering my WBC and caused me to become Neurtaphinic and i caught C-Diff), so I am now trying Methotrexate, but I got a blood clot on the lung (4 weeks ago). After I came out of hospital for a week, I was given Warfarin tablets (3 weeks ago) and ever since I've taken them, I have not passed ANY stools naturally. I went 8 days with no movement, so ended up using Microlex Enema to release some, which works, but I have been using them every day for the past 13 days as its the only thing that gets me 'going', only only some soft stools slide out (look normal and soft), so am I constipated or do I have a blockage, or are these drugs stopping me from having the "urge" to go. My belly is ever so bloated, tight and aches a little.
I am only 10.5 stone and 36 years old, I have a swollen face too....
I've only taken 3 doeses (one a week) of Methotrexate, so I think it is too early for any side affects of this drug to kick in yet (I began the Warfarin on the Friday and the Methotrexate on the Monday (3 weeks ago)...
Help please?.... as all the consultants and doctors say is "Try enemas and water etc bla bla...." but I am now dependent on the Microlex enema to go...
From this study (5 years ago):
Extreme constipation not responding to daily dose of Miralax fiber laxative with 3 Dulcolax tabs and water enema, for over one week. Trying to find nuke or rocket-propelled grenade, but I'm a middle-aged accountant and don't have the contacts. Am considering eating nothing but raisins for a week but not sure I can survive long enough for this to work. Also extremely depressed to the point of disorientation and almost constant suicidal ideation.
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Recent related drug studies:
- A study of drug interactions between Methotrexate, Warfarin Sodium for a patient with Inflammatory Bowel Disease - Ulcerative Colitis, Blood Clot - Lung. The patient has Constipation
- A study of drug interactions between Methotrexate Sodium, Naproxen, Folic Acid, Alprazolam, Hydrocodone Bitartrate And Acetaminophen for a patient with Psoriatic Arthritis, Arthritis - Psoriatic, Methotrexate - Serum, Anxiety. The patient has Depression, Constipation
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