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Review: could Methotrexate cause Deafness?

Summary: Deafness could be caused by Methotrexate, especially for people who are female, 10-19 old, have been taking the drug for 2 - 5 years, also take Humira, and have Rheumatoid arthritis.

We study 7,072 people who have side effects while taking Methotrexate from FDA and social media. Among them, 12 have Deafness. Find out below who they are, when they have Deafness and more.

On Apr, 10, 2014: 7,071 people reported to have side effects when taking Methotrexate sodium. Among them, 15 people (0.21%) have Deafness. They amount to 0.03% of all the 57,159 people who have Deafness on eHealthMe.

Trend of Deafness in Methotrexate sodium reports

Time on Methotrexate sodium when people have Deafness * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Deafness0.00%0.00%0.00%0.00%100.00%0.00%0.00%

Age of people who have Deafness when taking Methotrexate sodium * :

0-12-910-1920-2930-3940-4950-5960+
Deafness0.00%0.00%33.33%0.00%0.00%0.00%33.33%33.33%

Severity of Deafness when taking Methotrexate sodium ** :

leastmoderateseveremost severe
Deafness0.00%100.00%0.00%0.00%

How people recovered from Deafness ** :

n/a

Top conditions involved for these people * :

  1. Rheumatoid arthritis (8 people, 53.33%)
  2. Ill-defined disorder (1 people, 6.67%)
  3. Pain (1 people, 6.67%)
  4. Alopecia (1 people, 6.67%)
  5. Bipolar disorder (1 people, 6.67%)

Top co-used drugs for these people * :

  1. Humira (5 people, 33.33%)
  2. Folic acid (4 people, 26.67%)
  3. Prednisolone (4 people, 26.67%)
  4. Remicade (4 people, 26.67%)
  5. Enbrel (3 people, 20.00%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Methotrexate sodium, Deafness

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On eHealthMe, Methotrexate Sodium (methotrexate sodium) is often used for rheumatoid arthritis. Find out below the conditions Methotrexate Sodium is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Methotrexate Sodium used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (22 hours ago):

  • Trying to determine if the timing of these drugs- especially the weekly mtx- should be staggered during the day to ensure they are appropriately absorbed. Periodic seizures continue- about once a quarter.

    Reply

  • From this study (3 days ago):

  • I never had any symptoms of raynauds until is was put on methotrexate,and then Enbrel,and now Humira.I used a automotive laser thermometer to check my arm
    temp. which was 97 degrees,however my fingers on the same arm were between
    69-72 degrees.

    Reply

  • From this study (4 days ago):

  • Dosage for methotrexate is 15 to 17 mg. over ten year period.
    Have been taking about 800 mg. of frolic acid per day, plus whatever occurs naturally in food.
    For about a year have been dealing with urinary retention. Don't know if there is a connection.
    Will be seeing my doctor tomorrow .

    Also take generic Zantac

    Reply

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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