Review: could Methotrexate sodium cause Insomnia?
Summary: Insomnia is found among people who take Methotrexate sodium, especially for people who are female, 40-49 old, also take medication Folic acid, and have Rheumatoid arthritis.
We study 7,195 people who have side effects while taking Methotrexate sodium from FDA and social media. Among them, 54 have Insomnia. Find out below who they are, when they have Insomnia and more.
You are not alone: join a mobile support group for people who take Methotrexate sodium and have Insomnia >>>
Methotrexate sodium has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from 7,840 Methotrexate sodium users)
Insomnia (sleeplessness) has been reported by people with depression, quit smoking, pain, high blood pressure, stress and anxiety. (latest reports from 143,724 Insomnia patients)
On Jan, 6, 2015: 7,195 people reported to have side effects when taking Methotrexate sodium. Among them, 59 people (0.82%) have Insomnia.
Time on Methotrexate sodium when people have Insomnia * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
Age of people who have Insomnia when taking Methotrexate sodium * :
Severity of Insomnia when taking Methotrexate sodium ** :
|least||moderate||severe||most severe |
How people recovered from Insomnia ** :
|while on the drug||after off the drug||not yet |
Top conditions involved for these people * :
- Rheumatoid arthritis (57 people, 96.61%)
- Osteoporosis (16 people, 27.12%)
- Pain (16 people, 27.12%)
- Pain management (12 people, 20.34%)
- Vitamin b complex deficiency (12 people, 20.34%)
Top co-used drugs for these people * :
- Folic acid (26 people, 44.07%)
- Enbrel (25 people, 42.37%)
- Remicade (21 people, 35.59%)
- Prednisone (19 people, 32.20%)
- Fosamax (18 people, 30.51%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Do you have Insomnia while taking Methotrexate Sodium?
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- support group for people who take Methotrexate sodium and have Insomnia
- support group for people who take Methotrexate sodium
- support group for people who have Insomnia
Recent conversations of related support groups:
- Support group for people who have Insomnia
Hi Everyone - I am desperate to talk to people who suffer like me. I have RLS and insomnia. I take Mirapex, Gabapenten, and have tried about 6 different kinds of sleeping pills and for the last 3 years I sleep about 3 to 4 hours a night. I can fall asleep but I cannot stay asleep. I am so sick of living like this. Nothing helps to keep me asleep. I go to bed at the same time every night (9) and around 1:00am, I wake up to go to the bathroom then the nightmare begins.... I cannot go back to sleep. I feel tired, depressed, alone and desperate for help. I have been to the Mayo Clinic twice and to numerous doctors and although they try, I can't get better. I exercise everyday for 1 - 1&1/2 hrs a day. I do not have any other health issues at all. This is a real big problem and a awful way to live. I just feel so alone and sad.
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Comments from related studies:
From this study (1 month ago):
I have had insomnia off and on all my life until I turned 40 and the I was diagnosed with Psoriatic Arthritis and I was tired all the time and I was sleeping a lot for me and it was good to be able to sleep. The doctor put me on Methotrexate and Enbrel and I could still sleep not as much as before I started the drugs but better than before when I was younger. I went on and off the Enbrel and Methotrexate over the years. I took Adipex for about six months this year for weight loss and that is when I started taking Benadryl to sleep, after I stopped the Adipex and started the Enbrel again my insomnia is worse, I take 2 Benadryl and a 0.5 Xanax every night to sleep and most nights I still don't get to sleep before 1am and many nights even later, I get up at 7am everyday no mater what time I get to sleep and most of the time I am not tired when I wake up, it just really bothers me not being able to sleep when everyone else does.
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Sleep Apnea - treated with Cpap.
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Thrash around (awake, needing to move, repetition song or poem in head, no worries) in bed until about 6:00a.m. Then sleep about 3-4 hours. Exhausted. Losing weight. Don't take naps. Methotrexate at 10mg, folic acid at 1mg per day. Recently reduced folic acid to 5mcg daily, in hopes of improvement. This unrelenting cycle started when pharmacy switched my Advair for cheaper Dulera. After 2 months of about 3 hours of morning sleep only and 6 pounds lost, back to Advair. But imsomnia pattern continues, though with very slow weight gain (good, for me). Age 65. Only a 12.5mg CR Ambien works--so take it about 2X month. 5mg Ambien (generic) does not work. Afraid of taking Ambien often. Wonder if a sensitivity to the folic acid might be the likely culprit.
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