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Review: could Methotrexate sodium cause Insomnia?

Summary: Insomnia is found among people who take Methotrexate sodium, especially for people who are female, 40-49 old, also take medication Folic acid, and have Rheumatoid arthritis.

We study 7,195 people who have side effects while taking Methotrexate sodium from FDA and social media. Among them, 54 have Insomnia. Find out below who they are, when they have Insomnia and more.

You are not alone: join a mobile support group for people who take Methotrexate sodium and have Insomnia >>>

 

 

 

 

Methotrexate sodium

Methotrexate sodium has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from 7,840 Methotrexate sodium users)

Insomnia

Insomnia (sleeplessness) has been reported by people with depression, quit smoking, pain, high blood pressure, stress and anxiety. (latest reports from 143,888 Insomnia patients)

On Feb, 6, 2015: 7,195 people reported to have side effects when taking Methotrexate sodium. Among them, 59 people (0.82%) have Insomnia.

Trend of Insomnia in Methotrexate sodium reports

Time on Methotrexate sodium when people have Insomnia * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Insomnia16.67%8.33%0.00%25.00%25.00%0.00%25.00%

Age of people who have Insomnia when taking Methotrexate sodium * :

0-12-910-1920-2930-3940-4950-5960+
Insomnia0.00%0.00%6.25%0.00%4.69%40.62%28.12%20.31%

Severity of Insomnia when taking Methotrexate sodium ** :

leastmoderateseveremost severe
Insomnia0.00%33.33%66.67%0.00%

How people recovered from Insomnia ** :

while on the drugafter off the drugnot yet
Insomnia0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Rheumatoid arthritis (57 people, 96.61%)
  2. Osteoporosis (16 people, 27.12%)
  3. Pain (16 people, 27.12%)
  4. Pain management (12 people, 20.34%)
  5. Vitamin b complex deficiency (12 people, 20.34%)

Top co-used drugs for these people * :

  1. Folic acid (26 people, 44.07%)
  2. Enbrel (25 people, 42.37%)
  3. Remicade (21 people, 35.59%)
  4. Prednisone (19 people, 32.20%)
  5. Fosamax (18 people, 30.51%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of methotrexate sodium and insomnia on

Do you have Insomnia while taking Methotrexate Sodium?

You are not alone! Join a mobile support group:
- support group for people who take Methotrexate sodium and have Insomnia
- support group for people who take Methotrexate sodium
- support group for people who have Insomnia

Recent conversations of related support groups:

  • Support group for people who have Insomnia
    Hi Everyone - I am desperate to talk to people who suffer like me. I have RLS and insomnia. I take Mirapex, Gabapenten, and have tried about 6 different kinds of sleeping pills and for the last 3 years I sleep about 3 to 4 hours a night. I can fall asleep but I cannot stay asleep. I am so sick of living like this. Nothing helps to keep me asleep. I go to bed at the same time every night (9) and around 1:00am, I wake up to go to the bathroom then the nightmare begins.... I cannot go back to sleep. I feel tired, depressed, alone and desperate for help. I have been to the Mayo Clinic twice and to numerous doctors and although they try, I can't get better. I exercise everyday for 1 - 1&1/2 hrs a day. I do not have any other health issues at all. This is a real big problem and a awful way to live. I just feel so alone and sad.

Drugs in real world that are associated with:

Could your condition cause:

Can you answer these questions (Ask a question):

  • Does clonazapam cause tinnitus or ringing in the ears?
    Patient fell a year ago and injured her neck and broke a bone in her arm. Has had severe pain in her neck. Getting acupuncture frequently. Recently tried to change medication from Valium to Clonazepam, and developed severe tinnitus. She said she only missed two days of Valium. She also says she has skipped days without taking valium and never had a problem. She says Clonazepam caused the tinnitus. I can't find anything that states a side effect of clonazepam is tinnitus.
  • Does humira cause excessive sweating?
    Having psoriaticarthritis,fibromyalgia,psoriais,restless leg syndrome,roseacea and high blood pressure means complex health issues and a complex list of medication to go with it. Iam suffering extreme sweating,flushing and now a tickled cough. Now it could be due to going through the change (menopause) but that started a year ago and although I was getting the flushes and sweating,it was nothing like it is now! To me,it seems the excessive sweating started roughly a month after taking Humira. Having so many health issues I'm in tune with any changes and note and monitor them. I started Humira 10 months ago now. My Psoriasis has cleared completely so I'm really pleased. Usually,there's a trade off and you end up with something else! Could the issues I have be down to a single drug on the list,or a combination?
  • Would the tinnitus abate with if i discontinue methotrexate?
    I've just begun my 4th year of Methotrexate for Rheumatoid issue, but it also alleviated my psoriasis. I am hesitant to discontinue because the benefits are great. However, the tinnitus is becoming unbearable and almost maddening. I will more likely consider talking to my doctor about changing medications if 1. The tinnitus subsides with the discontinuance of Methotrexate and if 2. Other rheumatoid medication would not have the same issues with tinnitus. Just discovered the possible connection minutes ago and am eager and hopeful. Please help. Thank you. -Celeste
  • Can i take humira while i still have pinpoint red spots on my skin? i have been told to stop the methotrextrate and they started me on prednisone to clear it up, i am scheduled to start humira.
    I have been diagnosed with R/A and started taking Methotrextate and Folic Acid. I began to break out like I had the measles. Was told it was a reaction to the methotrextate. I was taken off of it and given a large dose of prednisone. My question is I am scheduled to start taking Humira injections and I have been off of the methotrextate 24 days and it has not cleared up yet. Is is safe to start the Humira injections?
  • What does unmasking mean; and does it mean that i always had hight cholesterol and triglycerides, or did actemra increase them?
    I have failed many RA meds, and now receive actemera x's 10 months I have never had high cholesterol or triglycerides and did not get my cholesterol checked except for the baseline 2/2014 and 12/2014 I was 198 TChol and now am 245; my tri up 85 points. my MD said that now that my inflammation is normal it shows my true cholestorol. I don't understand.

More questions for: Methotrexate sodium, Insomnia

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More reviews for: Methotrexate sodium, Insomnia

Comments from related studies:

  • From this study (2 months ago):

  • I have had insomnia off and on all my life until I turned 40 and the I was diagnosed with Psoriatic Arthritis and I was tired all the time and I was sleeping a lot for me and it was good to be able to sleep. The doctor put me on Methotrexate and Enbrel and I could still sleep not as much as before I started the drugs but better than before when I was younger. I went on and off the Enbrel and Methotrexate over the years. I took Adipex for about six months this year for weight loss and that is when I started taking Benadryl to sleep, after I stopped the Adipex and started the Enbrel again my insomnia is worse, I take 2 Benadryl and a 0.5 Xanax every night to sleep and most nights I still don't get to sleep before 1am and many nights even later, I get up at 7am everyday no mater what time I get to sleep and most of the time I am not tired when I wake up, it just really bothers me not being able to sleep when everyone else does.

    Reply

  • From this study (1 year ago):

  • Sleep Apnea - treated with Cpap.

    Reply

  • From this study (2 years ago):

  • Thrash around (awake, needing to move, repetition song or poem in head, no worries) in bed until about 6:00a.m. Then sleep about 3-4 hours. Exhausted. Losing weight. Don't take naps. Methotrexate at 10mg, folic acid at 1mg per day. Recently reduced folic acid to 5mcg daily, in hopes of improvement. This unrelenting cycle started when pharmacy switched my Advair for cheaper Dulera. After 2 months of about 3 hours of morning sleep only and 6 pounds lost, back to Advair. But imsomnia pattern continues, though with very slow weight gain (good, for me). Age 65. Only a 12.5mg CR Ambien works--so take it about 2X month. 5mg Ambien (generic) does not work. Afraid of taking Ambien often. Wonder if a sensitivity to the folic acid might be the likely culprit.

    Reply

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