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Review: could Methotrexate sodium cause Puffy face (Facial swelling)?

Summary: Puffy face is reported only by a few people who take Methotrexate sodium.

We study 7,195 people who have side effects while taking Methotrexate sodium from FDA and social media. Find out below who they are, when they have Puffy face and more.

You are not alone: join a mobile support group for people who take Methotrexate sodium and have Puffy face >>>

 

 

 

 

Methotrexate sodium

Methotrexate sodium has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from 7,840 Methotrexate sodium users)

Puffy face

Puffy face has been reported by people with high blood pressure, high blood cholesterol, depression, pain, hypothyroidism. (latest reports from 200 Puffy face patients)

On Jan, 2, 2015: 7,195 people reported to have side effects when taking Methotrexate sodium. Among them, 1 people (0.01%) has Puffy Face.

Trend of Puffy face in Methotrexate sodium reports

Time on Methotrexate sodium when people have Puffy face * :

n/a

Age of people who have Puffy face when taking Methotrexate sodium * :

0-12-910-1920-2930-3940-4950-5960+
Puffy face0.00%0.00%0.00%0.00%100.00%0.00%0.00%0.00%

Severity of Puffy face when taking Methotrexate sodium ** :

leastmoderateseveremost severe
Puffy face0.00%100.00%0.00%0.00%

How people recovered from Puffy face ** :

n/a

Top conditions involved for these people * :

  1. Anxiety disorder due to a general medical condition (1 people, 100.00%)
  2. Mrsa infection (1 people, 100.00%)
  3. Rheumatoid arthritis (1 people, 100.00%)
  4. Inflammatory bowel disease - ulcerative colitis (1 people, 100.00%)

Top co-used drugs for these people * :

  1. Xanax (1 people, 100.00%)
  2. Tetracycline hydrochloride - 100mg (1 people, 100.00%)
  3. Mercaptopurine (1 people, 100.00%)
  4. Prednisone - 10mg (1 people, 100.00%)
  5. Remicade (1 people, 100.00%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Puffy Face while taking Methotrexate Sodium?

You are not alone! Join a mobile support group:
- support group for people who take Methotrexate sodium and have Puffy Face
- support group for people who take Methotrexate sodium
- support group for people who have Puffy Face

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More questions for: Methotrexate sodium, Puffy face

You may be interested at these reviews (Write a review):

  • Humira: my experience
    I have had some form of arthritis probably since birth. My father and maternal grandfather had some form of arthritis. I began to realize pain in both ankles if I stood or walked too long.

    I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, sulfasalazine, etc. My best results came with methotrexate after I got cellulitis in my knee (scratch it while kayaking in the summer, fiberglass boat). It dropped my sed rate from over 100 to 35 or so within a few months. I continued with MTX from 1977 to 2000 when my MD suggested Enbrel and stopping MTX. That was a VERY bad decision. Enbrel appeared to mask the disease for a few years. I had my left MCP replaced in 2004, my right heel debrided in 2010, and both my TMJs replaced in 2012. I strongly believe that if I had kept with the MTX it would have delayed those changes. Additionally, in 2011 I was in a bus crash returning from RAGBRAI. I got knocked out from three to six minutes. I had a nasty concussion that lasted 2+ years. Towards the end of the third year post accident I started exercising more aggressively. After doing several 40, 50, and 60 miles rides, I took a leisurely 50 mile ride around Boston at night. Two days later I had a spinal edema. So much for biking and other active sports! :-(

    I have continued with MTX. Late 2013 my MD increased my MTX to .8/week. I had been taking .6/week. I stopped taking Enbrel and switched to Humira in early 2014. I took it for a few months before my doc and I realized it was not doing any better than Enbrel. I tried Humira for three months but it did not seem to work any better than Enbrel. In early June I stopped Humira and waited a few weeks before I started Otezla. I stopped Oterzla on 9/15/14 because it made me depressed and allowed my morning stiffness to get much worse.

    I started prednisone again from the start of July. By mid-August I told my MD that I was screaming louder than I ever had; my dog was very startled. I stopped it gradually over the next two weeks. Meanwhile, the Otezla made me feel awful.

    My MD is going to get me onto another injectable that I take monthly. I forget its name.
  • Nitrous oxide and mongoloidism
    On two separate dental visits I was given Nitrous Oxide. Each time my face became swollen, I looked Mongoloid. The swelling lasted a little over a month each time. No pain, just uncomfortable. I was breathing heavily and was left, unmonitored, to inhale the Nitrous Oxide for about 20 minutes before the dentist came in. I would like to know if a person who is Mongoloid is born with Nitrous Oxide in their brain or in their system that causes THEIR face to swell? Sincerely, Inabubble
  • Psoratic arthritis and trigeminal neuralgia
    hi i suffer from psorisis and psoratic athritis i was just diagnosed with trigeminal neuralgia i was looking for the connection between the two and i see that there is one from your study
    the thing is all 13 people in the study said to have psoriatic arthropathy yet only one said to have psoratic arthritis yet to the best of my knowledge it is the same condition just a diffrent name which means all those studied have psoratic arthritis like me
    also i have not been taking those medicines in the study yet i have the same condition so if you take me into account could be the oly conecction between all of us is the psorisis and psoratic arthritis and not the medicine
  • Spiriva caused me to swell up like a hippo.
    My Doctor prescribed spiriva to help me breathe due to asthma/cold. I never smoked but my parents and friends were heavy smokers. I used the spiriva 3 times. Once a day for 3 days then I started swelling in my ankles and the swelling continued until my face, hands arms... basically I was so swollen I gained 29 pounds in two days. My doctor put me on lasix and potassium for several weeks. I quit using the spiriva when my other doctor asked if I was on any new meds. Spiriva was the only new medicine. When I stopped using it the swelling went away.
  • Personalized review of arava (1 response)
    Have had RA for 10 years and was on Methotrexate those 10 years. Had nose bleeds which got progressively worse over the years and began to effect my quality of living. Doctor said it could NOT be the drug, but according to eHealth Me, it could. At urging of an ENT, I stopped taking Methotrexate and the nose bleeds have now almost completely stopped. My doctor put me on Arava 3 days ago and I am on eHealth to study the effects of it.

More reviews for: Methotrexate sodium, Puffy face

Comments from related studies:

  • From this study (3 days ago):

  • My chest begin after walking or cycling at a heart rate of 90-95 bpm for 5 minutes
    and increase in intensity for 10 minutes and a heart rate 100-105. The chest pains
    subside gradually and disappear after 5 more minutes of continued walking or cycling.

    I had the same condition before taking Folic acid and Methotrexate.

    Reply

  • From this study (5 days ago):

  • recurring vertigo that lasts from an hour to a couple of days per episode

    Reply

  • From this study (2 weeks ago):

  • Was put on metoprolol in October but discontinued for 5 days due to adverse affect and not being sure which med caused it. Began taking metoprolol again after 5 days of being off of it. Switched at that time from lisinopril to losartan 25 mg a day. Had no problems other than the inside of my mouth swelling from the metoprolol. About 2 weeks ago the metoprolol was increased from 12.5 mg to 25 mg. I now have angioedema and the dr says it's the losartan but I fully believe it's the metoprolol.

    Reply

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