Review: could Methotrexate cause Abdominal Cramps?


Summary

Abdominal cramps is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Humira, and have Rheumatoid arthritis . We study 191,458 people who have side effects while taking Methotrexate from FDA and social media. Among them, 2,966 have Abdominal cramps. Find out below who they are, when they have Abdominal cramps and more.

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Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 205,730 users)

Abdominal Cramps

Abdominal cramps has been reported by people with breathing difficulty, pain, drug ineffective, abdominal pain upper, abdominal pain (latest reports from 122,068 Abdominal cramps patients).

On Sep, 16, 2016

191,458 people reported to have side effects when taking Methotrexate.
Among them, 2,966 people (1.55%) have Abdominal Cramps


Number of reports submitted per year:

Could Methotrexate cause Abdominal cramps?

Time on Methotrexate when people have Abdominal Cramps *:

  • < 1 month: 34.95 %
  • 1 - 6 months: 12.46 %
  • 6 - 12 months: 11.25 %
  • 1 - 2 years: 13.98 %
  • 2 - 5 years: 13.68 %
  • 5 - 10 years: 9.42 %
  • 10+ years: 4.26 %

Gender of people who have Abdominal Cramps when taking Methotrexate *:

  • female: 71.9 %
  • male: 28.1 %

Age of people who have Abdominal Cramps when taking Methotrexate *:

  • 0-1: 0.29 %
  • 2-9: 5.62 %
  • 10-19: 12.64 %
  • 20-29: 6.73 %
  • 30-39: 7.77 %
  • 40-49: 14.09 %
  • 50-59: 22.64 %
  • 60+: 30.24 %

Severity if Abdominal Cramps when taking Methotrexate **:

  • least: 0.0 %
  • moderate: 62.5 %
  • severe: 18.75 %
  • most severe: 18.75 %

How people recovered from Abdominal Cramps **:

  • while on drug: 0.0 %
  • after off the drug: 13.33 %
  • not yet: 86.67 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (1,303 people, 43.93%)
  • Crohn's Disease (303 people, 10.22%)
  • Pain (182 people, 6.14%)
  • Psoriatic Arthropathy (172 people, 5.80%)
  • Hypertension (170 people, 5.73%)

Top co-used drugs for these people *:

  • Humira (801 people, 27.01%)
  • Folic Acid (697 people, 23.50%)
  • Prednisone (467 people, 15.75%)
  • Enbrel (421 people, 14.19%)
  • Remicade (260 people, 8.77%)

Top other side effects for these people *:

  • Diarrhoea (782 people, 26.37%)
  • Nausea (706 people, 23.80%)
  • Vomiting (650 people, 21.92%)
  • Pyrexia (467 people, 15.75%)
  • Arthralgia (350 people, 11.80%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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