Review: could Methotrexate cause Abdominal Cramps?


Summary

Abdominal cramps is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Folic Acid, and have Rheumatoid arthritis . We study 128,586 people who have side effects while taking Methotrexate from FDA and social media. Among them, 1,973 have Abdominal cramps. Find out below who they are, when they have Abdominal cramps and more.

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Methotrexate

It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 129,243 users)

Abdominal Cramps

Abdominal cramps has been reported by people with breathing difficulty, pain, abdominal pain upper, cholecystitis chronic, abdominal pain (latest reports from 75,742 Abdominal cramps patients).

On Jul, 23, 2016

128,586 people reported to have side effects when taking Methotrexate.
Among them, 1,973 people (1.53%) have Abdominal Cramps


Number of reports submitted per year:

Could Methotrexate cause Abdominal cramps?

Time on Methotrexate when people have Abdominal Cramps *:

  • < 1 month: 39.31 %
  • 1 - 6 months: 14.89 %
  • 6 - 12 months: 11.45 %
  • 1 - 2 years: 12.21 %
  • 2 - 5 years: 10.31 %
  • 5 - 10 years: 9.54 %
  • 10+ years: 2.29 %

Gender of people who have Abdominal Cramps when taking Methotrexate *:

  • female: 72.15 %
  • male: 27.85 %

Age of people who have Abdominal Cramps when taking Methotrexate *:

  • 0-1: 0.25 %
  • 2-9: 6.24 %
  • 10-19: 13.98 %
  • 20-29: 6.99 %
  • 30-39: 7.55 %
  • 40-49: 14.92 %
  • 50-59: 22.1 %
  • 60+: 27.97 %

Severity if Abdominal Cramps when taking Methotrexate **:

  • least: 5.26 %
  • moderate: 63.16 %
  • severe: 21.05 %
  • most severe: 10.53 %

How people recovered from Abdominal Cramps **:

  • while on drug: 0.0 %
  • after off the drug: 14.29 %
  • not yet: 85.71 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (789 people)
  • Crohn's Disease (132 people)
  • Pain (112 people)
  • Prophylaxis (99 people)
  • Hypertension (92 people)

Top co-used drugs for these people *:

  • Folic Acid (502 people)
  • Humira (446 people)
  • Prednisone (359 people)
  • Enbrel (278 people)
  • Remicade (181 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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