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Review: could Methotrexate cause Back pain?

Summary: Back pain could be caused by Methotrexate, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take Folic acid, and have Rheumatoid arthritis.

We study 129,658 people who have side effects while taking Methotrexate from FDA and social media. Among them, 2,082 have Back pain. Find out below who they are, when they have Back pain and more.

On Apr, 10, 2014: 129,615 people reported to have side effects when taking Methotrexate. Among them, 2,082 people (1.61%) have Back Pain. They amount to 0.31% of all the 667,909 people who have Back Pain on eHealthMe.

Trend of Back pain in Methotrexate reports

Time on Methotrexate when people have Back pain * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Back pain26.45%20.65%14.19%16.77%5.16%9.68%7.10%

Gender of people who have Back pain when taking Methotrexate * :

FemaleMale
Back pain77.32%22.68%

Age of people who have Back pain when taking Methotrexate * :

0-12-910-1920-2930-3940-4950-5960+
Back pain0.06%2.01%3.68%2.84%7.08%18.28%22.91%43.14%

Severity of Back pain when taking Methotrexate ** :

leastmoderateseveremost severe
Back pain0.00%100.00%0.00%0.00%

How people recovered from Back pain ** :

while on the drugafter off the drugnot yet
Back pain0.00%50.00%50.00%

Top conditions involved for these people * :

  1. Rheumatoid arthritis (1,097 people, 52.69%)
  2. Osteoporosis (217 people, 10.42%)
  3. Pain (184 people, 8.84%)
  4. Psoriatic arthropathy (122 people, 5.86%)
  5. Hypertension (115 people, 5.52%)

Top co-used drugs for these people * :

  1. Folic acid (745 people, 35.78%)
  2. Humira (620 people, 29.78%)
  3. Prednisone (510 people, 24.50%)
  4. Enbrel (508 people, 24.40%)
  5. Remicade (349 people, 16.76%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Methotrexate, Back pain

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On eHealthMe, Methotrexate (methotrexate sodium) is often used for rheumatoid arthritis. Find out below the conditions Methotrexate is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Methotrexate used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (19 hours ago):

  • Trying to determine if the timing of these drugs- especially the weekly mtx- should be staggered during the day to ensure they are appropriately absorbed. Periodic seizures continue- about once a quarter.

    Reply

  • From this study (3 days ago):

  • I never had any symptoms of raynauds until is was put on methotrexate,and then Enbrel,and now Humira.I used a automotive laser thermometer to check my arm
    temp. which was 97 degrees,however my fingers on the same arm were between
    69-72 degrees.

    Reply

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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