Review: could Methotrexate cause Back pain?
Summary: Back pain is found among people who take Methotrexate, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take medication Folic acid, and have Rheumatoid arthritis.
We study 129,897 people who have side effects while taking Methotrexate from FDA and social media. Among them, 2,084 have Back pain. Find out below who they are, when they have Back pain and more.
You are not alone: join a mobile support group for people who take Methotrexate and have Back pain >>>
Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from 131,243 Methotrexate users)
Back pain has been reported by people with osteoporosis, multiple sclerosis, pain, high blood pressure, rheumatoid arthritis. (latest reports from 107,077 Back pain patients)
On Feb, 25, 2015: 129,897 people reported to have side effects when taking Methotrexate. Among them, 2,084 people (1.60%) have Back Pain.
Time on Methotrexate when people have Back pain * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Back pain||26.11%||20.38%||14.65%||16.56%||5.10%||10.19%||7.01% |
Gender of people who have Back pain when taking Methotrexate * :
|Back pain||77.34%||22.66% |
Age of people who have Back pain when taking Methotrexate * :
|Back pain||0.06%||2.00%||3.67%||2.84%||7.07%||18.26%||22.88%||43.21% |
Severity of Back pain when taking Methotrexate ** :
|least||moderate||severe||most severe |
|Back pain||0.00%||75.00%||25.00%||0.00% |
How people recovered from Back pain ** :
|while on the drug||after off the drug||not yet |
|Back pain||0.00%||25.00%||75.00% |
Top conditions involved for these people * :
- Rheumatoid arthritis (1,098 people, 52.69%)
- Osteoporosis (217 people, 10.41%)
- Pain (184 people, 8.83%)
- Psoriatic arthropathy (122 people, 5.85%)
- Hypertension (115 people, 5.52%)
Top co-used drugs for these people * :
- Folic acid (746 people, 35.80%)
- Humira (620 people, 29.75%)
- Prednisone (511 people, 24.52%)
- Enbrel (509 people, 24.42%)
- Remicade (349 people, 16.75%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
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- Does humira cause excessive sweating?
Having psoriaticarthritis,fibromyalgia,psoriais,restless leg syndrome,roseacea and high blood pressure means complex health issues and a complex list of medication to go with it. Iam suffering extreme sweating,flushing and now a tickled cough. Now it could be due to going through the change (menopause) but that started a year ago and although I was getting the flushes and sweating,it was nothing like it is now! To me,it seems the excessive sweating started roughly a month after taking Humira. Having so many health issues I'm in tune with any changes and note and monitor them. I started Humira 10 months ago now. My Psoriasis has cleared completely so I'm really pleased. Usually,there's a trade off and you end up with something else! Could the issues I have be down to a single drug on the list,or a combination?
- Would the tinnitus abate with if i discontinue methotrexate?
I've just begun my 4th year of Methotrexate for Rheumatoid issue, but it also alleviated my psoriasis. I am hesitant to discontinue because the benefits are great. However, the tinnitus is becoming unbearable and almost maddening. I will more likely consider talking to my doctor about changing medications if 1. The tinnitus subsides with the discontinuance of Methotrexate and if 2. Other rheumatoid medication would not have the same issues with tinnitus. Just discovered the possible connection minutes ago and am eager and hopeful. Please help. Thank you. -Celeste
- Kindly tell me whether this treatment is accurate for spine tb?
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- Can i take humira while i still have pinpoint red spots on my skin? i have been told to stop the methotrextrate and they started me on prednisone to clear it up, i am scheduled to start humira.
I have been diagnosed with R/A and started taking Methotrextate and Folic Acid. I began to break out like I had the measles. Was told it was a reaction to the methotrextate. I was taken off of it and given a large dose of prednisone. My question is I am scheduled to start taking Humira injections and I have been off of the methotrextate 24 days and it has not cleared up yet. Is is safe to start the Humira injections?
More questions for: Methotrexate, Back pain
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I have had some form of arthritis probably since birth. My father and maternal grandfather had some form of arthritis. I began to realize pain in both ankles if I stood or walked too long.
I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, sulfasalazine, etc. My best results came with methotrexate after I got cellulitis in my knee (scratch it while kayaking in the summer, fiberglass boat). It dropped my sed rate from over 100 to 35 or so within a few months. I continued with MTX from 1977 to 2000 when my MD suggested Enbrel and stopping MTX. That was a VERY bad decision. Enbrel appeared to mask the disease for a few years. I had my left MCP replaced in 2004, my right heel debrided in 2010, and both my TMJs replaced in 2012. I strongly believe that if I had kept with the MTX it would have delayed those changes. Additionally, in 2011 I was in a bus crash returning from RAGBRAI. I got knocked out from three to six minutes. I had a nasty concussion that lasted 2+ years. Towards the end of the third year post accident I started exercising more aggressively. After doing several 40, 50, and 60 miles rides, I took a leisurely 50 mile ride around Boston at night. Two days later I had a spinal edema. So much for biking and other active sports! :-(
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I started prednisone again from the start of July. By mid-August I told my MD that I was screaming louder than I ever had; my dog was very startled. I stopped it gradually over the next two weeks. Meanwhile, the Otezla made me feel awful.
My MD is going to get me onto another injectable that I take monthly. I forget its name.
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hi i suffer from psorisis and psoratic athritis i was just diagnosed with trigeminal neuralgia i was looking for the connection between the two and i see that there is one from your study
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Comments from related studies:
From this study (6 days ago):
I had the flu for two weeks it has been gone two weeks but I stayed fatigued with dry cough. I had my infusion of Simponi Aria 10 days ago. My Methotrexate injection is due tomorrow.
NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.
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