Review: could Methotrexate cause Basal Cell Carcinoma?


Summary

Basal cell carcinoma is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for 2 - 5 years, also take medication Folic Acid, and have Rheumatoid arthritis . We study 191,458 people who have side effects while taking Methotrexate from FDA and social media. Among them, 983 have Basal cell carcinoma. Find out below who they are, when they have Basal cell carcinoma and more.

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Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 205,727 users)

Basal Cell Carcinoma

Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills) has been reported by people with ageusia, weight decreased, death, rashes, hair loss (latest reports from 8,766 Basal cell carcinoma patients).

On Sep, 16, 2016

191,458 people reported to have side effects when taking Methotrexate.
Among them, 983 people (0.51%) have Basal Cell Carcinoma


Number of reports submitted per year:

Could Methotrexate cause Basal cell carcinoma?

Time on Methotrexate when people have Basal Cell Carcinoma *:

  • < 1 month: 12.12 %
  • 1 - 6 months: 9.09 %
  • 6 - 12 months: 6.06 %
  • 1 - 2 years: 16.67 %
  • 2 - 5 years: 24.24 %
  • 5 - 10 years: 22.73 %
  • 10+ years: 9.09 %

Gender of people who have Basal Cell Carcinoma when taking Methotrexate *:

  • female: 67.16 %
  • male: 32.84 %

Age of people who have Basal Cell Carcinoma when taking Methotrexate *:

  • 0-1: 0.0 %
  • 2-9: 0.56 %
  • 10-19: 0.56 %
  • 20-29: 1.13 %
  • 30-39: 1.27 %
  • 40-49: 10.28 %
  • 50-59: 19.3 %
  • 60+: 66.76 %

Severity if Basal Cell Carcinoma when taking Methotrexate **:

  • least: 0.0 %
  • moderate: 0.0 %
  • severe: 100 %
  • most severe: 0.0 %

How people recovered from Basal Cell Carcinoma **:

  • while on drug: 50 %
  • after off the drug: 50 %
  • not yet: 0.0 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (572 people, 58.19%)
  • Psoriatic Arthropathy (59 people, 6.00%)
  • Osteoporosis (56 people, 5.70%)
  • Crohn's Disease (44 people, 4.48%)
  • Psoriasis (43 people, 4.37%)

Top co-used drugs for these people *:

  • Folic Acid (368 people, 37.44%)
  • Remicade (331 people, 33.67%)
  • Prednisone (154 people, 15.67%)
  • Humira (150 people, 15.26%)
  • Enbrel (110 people, 11.19%)

Top other side effects for these people *:

  • Pain (77 people, 7.83%)
  • Squamous Cell Carcinoma (71 people, 7.22%)
  • Osteoarthritis (60 people, 6.10%)
  • Fall (60 people, 6.10%)
  • Depression (57 people, 5.80%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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