Methotrexate and Bone density loss - from FDA reports
Bone density loss is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for 5 - 10 years, also take medication Folic Acid, and have Rheumatoid arthritis . We study 209,150 people who have side effects while taking Methotrexate from FDA. Among them, 202 have Bone density loss. Find out below who they are, when they have Bone density loss and more.
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Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 212,560 users)
Bone Density Loss
Bone density loss has been reported by people with osteoporosis, osteopenia, gastrooesophageal reflux disease, depression, high blood pressure (latest reports from 9,805 Bone density loss patients).
On Feb, 01, 2017
209,150 people reported to have side effects when taking Methotrexate.
Among them, 202 people (0.1%) have Bone Density Loss
Number of reports submitted per year:
Time on Methotrexate when people have Bone Density Loss *:
- < 1 month: 5.56 %
- 1 - 6 months: 11.11 %
- 6 - 12 months: 16.67 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 33.33 %
- 5 - 10 years: 33.33 %
- 10+ years: 0.0 %
Gender of people who have Bone Density Loss when taking Methotrexate *:
- female: 84.02 %
- male: 15.98 %
Age of people who have Bone Density Loss when taking Methotrexate *:
- 0-1: 1.76 %
- 2-9: 5.29 %
- 10-19: 5.88 %
- 20-29: 0.59 %
- 30-39: 7.06 %
- 40-49: 2.94 %
- 50-59: 30.0 %
- 60+: 46.47 %
Top conditions involved for these people *:
- Rheumatoid Arthritis (102 people, 50.50%)
- Osteoporosis (41 people, 20.30%)
- Breast Cancer Metastatic (33 people, 16.34%)
- Breast Cancer (29 people, 14.36%)
- Preventive Health Care (28 people, 13.86%)
Top co-used drugs for these people *:
- Folic Acid (58 people, 28.71%)
- Prednisone (52 people, 25.74%)
- Zometa (50 people, 24.75%)
- Aredia (49 people, 24.26%)
- Fosamax (42 people, 20.79%)
Top other side effects for these people *:
- Nausea (63 people, 31.19%)
- Diarrhea (59 people, 29.21%)
- Nausea And Vomiting (55 people, 27.23%)
- Osteoarthritis (53 people, 26.24%)
- Joint Pain (52 people, 25.74%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
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Can you answer these questions?
I started a low dose (10 mg) of methotrexate for rheumatoid arthritis last week and noticed this week, after taking my second does, that my face is breaking out. Does anyone have any similar experiences? I also take 5 mg of folic acid daily. Thanks for any help you can offer up.
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Hi there, My names Adele I am 41 and have RA. I had my Gall Bladder removed in March of this year due to stones and constant infections. 2 years ago I stopped taking MTX subcutaneous and unfortunately my RA has progressed to a point I have (today) re-started these. I have headache, nausea and ...
Several years ago in 2013 I was"diagnosed" with RA. I went through every medication including, humira, embral, to now IV fusions of remicade which has been almost a year. I am not feeling any better and body aches and joint pains getting worse. I started researching my symptoms and lyme kept ...
This is for my father. Shortly after starting methotrexate injections and cortisone for Rheumatoid arthritis my father started having language difficulties and now has dementia. He was diagnosed with Pick's disease. Could it be caused by these drugs? He is still taking them.
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