Review: could Methotrexate cause Bone density loss (Bone Density Decreased)?
Summary: Bone density loss is found among people who take Methotrexate, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Folic acid, and have Rheumatoid arthritis.
We study 129,908 people who have side effects while taking Methotrexate from FDA and social media. Among them, 135 have Bone density loss. Find out below who they are, when they have Bone density loss and more.
You are not alone: join a support group for people who take Methotrexate and have Bone density loss >>>
Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from 131,259 Methotrexate users)
Bone density loss
Bone density loss has been reported by people with osteoporosis, osteopenia, depression, breast cancer, high blood pressure. (latest reports from 6,637 Bone density loss patients)
On Apr, 1, 2015: 129,908 people reported to have side effects when taking Methotrexate. Among them, 135 people (0.10%) have Bone Density Loss.
Time on Methotrexate when people have Bone density loss * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Bone density loss||0.00%||9.09%||27.27%||0.00%||45.45%||18.18%||0.00% |
Gender of people who have Bone density loss when taking Methotrexate * :
|Bone density loss||89.13%||10.87% |
Age of people who have Bone density loss when taking Methotrexate * :
|Bone density loss||0.00%||3.20%||1.60%||0.00%||13.60%||1.60%||33.60%||46.40% |
Severity of Bone density loss when taking Methotrexate ** :
How people recovered from Bone density loss ** :
Top conditions involved for these people * :
- Rheumatoid arthritis (65 people, 48.15%)
- Osteoporosis (40 people, 29.63%)
- Breast cancer metastatic (32 people, 23.70%)
- Breast cancer (25 people, 18.52%)
- Prophylaxis (24 people, 17.78%)
Top co-used drugs for these people * :
- Folic acid (49 people, 36.30%)
- Zometa (47 people, 34.81%)
- Aredia (47 people, 34.81%)
- Fosamax (45 people, 33.33%)
- Prednisone (45 people, 33.33%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Do you have Bone Density Loss while taking Methotrexate?
You are not alone! Join a mobile support group on :
- support group for people who take Methotrexate and have Bone Density Loss
- support group for people who take Methotrexate
Drugs in real world that are associated with:
Could your condition cause:
- A study of drug interactions between Folic Acid, Asacol, Plaquenil, Methotrexate, Stelara for a 19-year old boy with Lupus-like Syndrome, Crohn's Disease. The patient has Acne Rosacea
- A study of drug interactions between Calcium Acetate, Multivitamin, Levothyroxine Sodium, Folic Acid, Methotrexate for a 56-year old woman with Flat Bones, General Health, Low Thyroid, Psoriatic Arthritis. The patient has Jaw Inflammation
- A study of side effects of Methotrexate for a 40-year old woman with Rheumatoid Arthritis. The patient has Elevated Mood
- A study of side effects of Methotrexate for a 53-year old woman with Rheumatoid Arthritis. The patient has Hearing Loss, Ringing In The Ears (a ringing in the ears)
- A study of side effects of Methotrexate for a 71-year old man with RA. The patient has Itching - Burning Eyes, Muscle Weakness (a lack of muscle strength)
Recent Methotrexate related drug comparison:
NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.