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Review: could Methotrexate cause Coughing (Cough)?

We study 129,775 people who have side effects while taking Methotrexate from FDA and social media. Among them, 3,110 have Coughing. Find out below who they are, when they have Coughing and more.

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Methotrexate

Methotrexate (latest outcomes from 131,127 users) has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis.

Coughing

Coughing (latest reports from 488,304 patients) has been reported by people with rheumatoid arthritis, high blood pressure, asthma, osteoporosis, high blood cholesterol.

On Sep, 16, 2014: 129,775 people reported to have side effects when taking Methotrexate. Among them, 3,110 people (2.40%) have Coughing.

Trend of Coughing in Methotrexate reports

Time on Methotrexate when people have Coughing * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Coughing16.54%23.46%10.38%12.69%15.38%11.15%10.38%

Gender of people who have Coughing when taking Methotrexate * :

FemaleMale
Coughing73.75%26.25%

Age of people who have Coughing when taking Methotrexate * :

0-12-910-1920-2930-3940-4950-5960+
Coughing0.15%3.44%3.55%2.53%7.55%14.46%27.14%41.19%

Severity of Coughing when taking Methotrexate ** :

leastmoderateseveremost severe
Coughing10.00%60.00%30.00%0.00%

How people recovered from Coughing ** :

while on the drugafter off the drugnot yet
Coughing0.00%14.29%85.71%

Top conditions involved for these people * :

  1. Rheumatoid arthritis (1,836 people, 59.04%)
  2. Pain (192 people, 6.17%)
  3. Hypertension (160 people, 5.14%)
  4. Psoriatic arthropathy (159 people, 5.11%)
  5. Vitamin supplementation (152 people, 4.89%)

Top co-used drugs for these people * :

  1. Humira (1,079 people, 34.69%)
  2. Enbrel (1,062 people, 34.15%)
  3. Folic acid (1,039 people, 33.41%)
  4. Prednisone (667 people, 21.45%)
  5. Remicade (387 people, 12.44%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Coughing while taking Methotrexate?

Get connected! Join a mobile support group:
- group for people who take Methotrexate and have Coughing
- group for people who take Methotrexate

Comments from related studies:

  • From this study (1 week ago):

  • Sarcoidosis caused complete heart block. Pacemaker implanted in December 2009 but for the past two years I have had palpitations caused by around 3.7 million ectopic heartbeats per year.

    Sarcoidosis also in lungs and eyes. Extended use of Pred Forte caused development of cataracts, one of which has been removed and I am awaiting the second operation.

    Breathlessness is caused by lack of oxygen entering the bloodstream and my ongoing heart problems

    Rarely able to sleep properly due to pain, sleeping for about 20 minutes at a time when I become so exhausted that the pain can't keep me awake

    Muscle and joint pain have made me weak and clumsy.Pain is felt all over, from head to toes along with muscle cramps and intense burning sensation to skin on lower legs.

    ACE levels fluctuate but average 110 - 150.

    Blood pressure on average is 150 / 78 - no treatment given

    I also take Nefopam Hydrochloride (Acupan) for pain but this drug is not on the list.

    Immobility, fatigue and constant pain have left me very depressed ad harbouring thoughts of suicide. My 15 year old granddaughter has lived with me since the death of my daughter 11 years ago and it is my hope that I will live long enough to see her settled in college and independent after which the only thing I have to look forward to is to end my own suffering.

    Reply

    Kath Nugent on Aug, 26, 2014:

    I was diagnosed with Lymphatic Sarcoidosis 15 years ago. After massive weight loss, a node in my neck the size of a small egg, and at the same time an
    area of my gum opened up were i had a tooth removed 20 years earlier, Sarcoid grew out of this opening !!it was like a piece of green string. My GP & Consultant tried to pull it out but failed,it was about an inch long. i was sent away with no further appointment, So i went to see my Dentist who seemed to know what it was and sent me to the Hospital Dentist who did a jaw bone Scraping and arranged for the node in neck to be removed for biopsy, both biopsy came back as Sarcoidosis. i was then x rayed and was found to have it in on my lungs as well. at this point i had active Sarcoidosis in my Lymphatic system, bone, lungs. However it as never been active in my lungs !!! it did however eat away the inside of my nose, it attacked my eyes i almost went blind, i lost my balance,it was in my brain.
    i was so tired, and after so many steroids i was having a bad reaction to them in various organs and was taken of them. i did recover from this as the Sarcoid went dormant. i have recently been diagnosed with a brain tumor and raised platelets. given that Sarcoidosis is next door to Cancer and that i feel absolutely wasted and week!!! i am feeling anxious about the outcome of more tests. But we all have to go sometime and i know there are people out there worse than me !!! i send you all love & light and hope we can all have the strength to help each other through whatever is thrown at us!! not easy by any means. Happy to answer any questions if it will help anyone Take care Kath Nugent

    Reply

  • From this study (6 months ago):

  • I am trying to find out why I get severe edema in feet legs arms and abdomin which goes away in a day with legs up and if I should be put on antibiotics asap do bronchitis doesn't turn into pneumonia. Slso why mu primary and pulmonary doctors are afraid to treat me while on ra drugs. They seem uneducated on ra meds.

    Reply

  • From this study (6 months ago):

  • I just begsn tx for rs using safest meds possible but did not yolerste pills so we are doing injections once a week but since we started I developed abdom ook nal edema plus whole body especially feet which subsided ptior to msjor orgsn testing hestt kidney bloodwotk a nd liver ultra sound. Results were normsl all in but kidney workup. We are trying to get to third week of methotrexate tx becausr the last uri which my ra dr treated immediately with snyibiotics my ra pain seemed much better I just had abdominal swelling and pressure on lungs thrn and yhis time entire body swelled dr rulled out ra it was edrma order err d tests with bed rest feet up over weekend causing edema to go away prior to echo and ultra sound. Tests were normal so went to pulmonologist to get help breathing and they were sfraid to use antibiotics just like my primary dr brgore they know nothing about my ra drugs so how am I supposed to stop this from going inyo pneumonia?

    Reply

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On eHealthMe, Methotrexate (methotrexate sodium) is often used for rheumatoid arthritis. Find out below the conditions Methotrexate is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

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