Could Methotrexate cause Coughing - from FDA reports


Summary

Coughing is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for 1 - 6 months, also take medication Enbrel, and have Rheumatoid arthritis . We study 197,034 people who have side effects while taking Methotrexate from FDA. Among them, 5,105 have Coughing. Find out below who they are, when they have Coughing and more.

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Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 212,494 users)

Coughing

Coughing has been reported by people with rheumatoid arthritis, high blood pressure, asthma, multiple sclerosis, chronic obstructive pulmonary disease (latest reports from 133,568 Coughing patients).

On Nov, 21, 2016

197,034 people reported to have side effects when taking Methotrexate.
Among them, 5,105 people (2.59%) have Coughing


Number of reports submitted per year:

Could Methotrexate cause Coughing?

Time on Methotrexate when people have Coughing *:

  • < 1 month: 17.21 %
  • 1 - 6 months: 23.38 %
  • 6 - 12 months: 11.36 %
  • 1 - 2 years: 13.31 %
  • 2 - 5 years: 9.74 %
  • 5 - 10 years: 15.26 %
  • 10+ years: 9.42 %

Gender of people who have Coughing when taking Methotrexate *:

  • female: 76.46 %
  • male: 23.54 %

Age of people who have Coughing when taking Methotrexate *:

  • 0-1: 0.15 %
  • 2-9: 2.81 %
  • 10-19: 3.32 %
  • 20-29: 3.0 %
  • 30-39: 6.03 %
  • 40-49: 13.58 %
  • 50-59: 29.01 %
  • 60+: 42.1 %

Severity of Coughing **:

  • least: 12.5 %
  • moderate: 62.5 %
  • severe: 25.0 %
  • most severe: 0.0 %

Top co-used drugs for these people *:

  • Enbrel (1,643 people, 32.18%)
  • Humira (1,569 people, 30.73%)
  • Folic Acid (1,304 people, 25.54%)
  • Prednisone (791 people, 15.49%)
  • Folic Acid. (451 people, 8.83%)

Forecasts by ePatient.care (We will alert you to new symptoms or undetected conditions when you take Methotrexate, learn more )

Potential co-existing conditions

  • High Blood Pressure (353 people, 6.91%)
  • Pain (282 people, 5.52%)

Potential co-existing symptoms

  • Fever (1,140 people, 22.33%)
  • Breathing Difficulty (857 people, 16.79%)
  • Nasopharyngitis (681 people, 13.34%)
  • Fatigue (653 people, 12.79%)
  • Joint Pain (607 people, 11.89%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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