Who have Dehydration with Methotrexate?


Dehydration is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Folic Acid, and have Rheumatoid arthritis . We study 197,034 people who have side effects while taking Methotrexate from FDA and social media. Among them, 1,585 have Dehydration. Find out below who they are, when they have Dehydration and more.

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Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 212,494 users)


Dehydration (dryness resulting from the removal of water) has been reported by people with high blood pressure, multiple sclerosis, pain, multiple myeloma, hepatitis c (latest reports from 94,592 Dehydration patients).

On Nov, 26, 2016

197,034 people reported to have side effects when taking Methotrexate.
Among them, 1,585 people (0.8%) have Dehydration

Number of reports submitted per year:

Could Methotrexate cause Dehydration?

Time on Methotrexate when people have Dehydration *:

  • < 1 month: 34.76 %
  • 1 - 6 months: 9.76 %
  • 6 - 12 months: 10.37 %
  • 1 - 2 years: 9.15 %
  • 2 - 5 years: 20.12 %
  • 5 - 10 years: 6.71 %
  • 10+ years: 9.15 %

Gender of people who have Dehydration when taking Methotrexate *:

  • female: 70.98 %
  • male: 29.02 %

Age of people who have Dehydration when taking Methotrexate *:

  • 0-1: 0.72 %
  • 2-9: 3.82 %
  • 10-19: 9.94 %
  • 20-29: 2.15 %
  • 30-39: 5.81 %
  • 40-49: 11.46 %
  • 50-59: 17.9 %
  • 60+: 48.21 %

Top co-used drugs for these people *:

  • Folic Acid (469 people, 29.59%)
  • Prednisone (314 people, 19.81%)
  • Humira (307 people, 19.37%)
  • Remicade (226 people, 14.26%)
  • Enbrel (209 people, 13.19%)

Forecasts by ePatient.care (We will alert you to new symptoms or undetected conditions when you take Methotrexate, learn more )

Potential co-existing conditions

  • Osteoporosis (120 people, 7.57%)
  • High Blood Pressure (107 people, 6.75%)
  • Crohn's Disease (83 people, 5.24%)

Potential co-existing symptoms

  • Nausea And Vomiting (372 people, 23.47%)
  • Diarrhea (345 people, 21.77%)
  • Nausea (332 people, 20.95%)
  • Fever (290 people, 18.30%)
  • Weakness (211 people, 13.31%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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