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Home > Methotrexate > Diarrhoea > Methotrexate and Diarrhoea

Review: could Methotrexate cause Diarrhoea (Diarrhea)?

Summary: Diarrhoea is found among people who take Methotrexate, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take medication Folic acid, and have Rheumatoid arthritis.

We study 129,841 people who have side effects while taking Methotrexate from FDA and social media. Among them, 3,139 have Diarrhoea. Find out below who they are, when they have Diarrhoea and more.

You are not alone: join a mobile support group for people who take Methotrexate and have Diarrhoea >>>

Methotrexate

Methotrexate (latest outcomes from 131,185 users) has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis.

Diarrhoea

Diarrhoea (latest reports from 1,112,574 patients) has been reported by people with high blood pressure, pain, depression, rheumatoid arthritis, osteoporosis.

On Oct, 26, 2014: 129,821 people reported to have side effects when taking Methotrexate. Among them, 3,859 people (2.97%) have Diarrhoea.

Trend of Diarrhoea in Methotrexate reports

Time on Methotrexate when people have Diarrhoea * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Diarrhoea48.52%20.35%5.22%5.39%13.04%4.87%2.61%

Gender of people who have Diarrhoea when taking Methotrexate * :

FemaleMale
Diarrhoea71.53%28.47%

Age of people who have Diarrhoea when taking Methotrexate * :

0-12-910-1920-2930-3940-4950-5960+
Diarrhoea0.93%5.55%7.66%4.08%7.86%13.10%24.23%36.59%

Severity of Diarrhoea when taking Methotrexate ** :

leastmoderateseveremost severe
Diarrhoea6.67%60.00%20.00%13.33%

How people recovered from Diarrhoea ** :

while on the drugafter off the drugnot yet
Diarrhoea0.00%20.00%80.00%

Top conditions involved for these people * :

  1. Rheumatoid arthritis (1,668 people, 43.22%)
  2. Pain (256 people, 6.63%)
  3. Prophylaxis (236 people, 6.12%)
  4. Osteoporosis (217 people, 5.62%)
  5. Hypertension (209 people, 5.42%)

Top co-used drugs for these people * :

  1. Folic acid (1,150 people, 29.80%)
  2. Prednisone (926 people, 24.00%)
  3. Humira (835 people, 21.64%)
  4. Enbrel (784 people, 20.32%)
  5. Remicade (456 people, 11.82%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Diarrhoea while taking Methotrexate?

You are not alone! Join a mobile support group:
- support group for people who take Methotrexate and have Diarrhoea
- support group for people who take Methotrexate
- support group for people who have Diarrhoea

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  • Humira: my experience
    (Posted by a 66 year old man who has Ankylosing Spondylitis, Reiter's Syndrome, Psoriatic Arthritis, and takes Methotrexate Preservative Free, Enbrel, Humira)
    I have had some form of arthritis probably since birth. My father and maternal grandfather had some form of arthritis. I began to realize pain in both ankles if I stood or walked too long. I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, ...

  • Psoratic arthritis and trigeminal neuralgia
    (Posted by a 33 year old man who has Nasal Septum Deviation, Psoriasis, Psoriatic Arthritis, Trigeminal Neuralgia, Asthma Exercise Induced, and takes Methotrexate)
    hi i suffer from psorisis and psoratic athritis i was just diagnosed with trigeminal neuralgia i was looking for the connection between the two and i see that there is one from your study the thing is all 13 people in the study said to have psoriatic arthropathy yet only one said to have psoratic a ...

  • Spiriva caused me to swell up like a hippo.
    (Posted by a 46 year old woman who has Rheumatoid Arthritis, Irritable Bowel Syndrome, and takes Advair Diskus 250/50, Methotrexate, Plaquenil, Metformin, Klonopin, Zanaflex, Prednisone, Singulair, Imitrex, Nexium)
    My Doctor prescribed spiriva to help me breathe due to asthma/cold. I never smoked but my parents and friends were heavy smokers. I used the spiriva 3 times. Once a day for 3 days then I started swelling in my ankles and the swelling continued until my face, hands arms... basically I was so swollen ...

  • Isoniazid: the downside continued
    (Posted by a 62 year old woman who has Fatigue, Dizziness (excl Vertigo), Nausea, Impaired Healing, Liver Pain, Diarrhea, Hair Thinning, Liver Pain, Skin Atrophy, and takes Isoniazid)
    I also have extreme fatigue. I can sleep 8 hours and then take a 4 hour nap. I have dizziness which seems to be increasing in the last few weeks. I have nausea on and off. I have diarrhea in the morning 45 minutes after taking it. Then I am mostly constipated for the rest of the day. It seems ...

  • Personalized review of arava
    (Posted by a 65 year old woman who has Rheumatoid Arthritis, and takes Methotrexate)
    Have had RA for 10 years and was on Methotrexate those 10 years. Had nose bleeds which got progressively worse over the years and began to effect my quality of living. Doctor said it could NOT be the drug, but according to eHealth Me, it could. At urging of an ENT, I stopped taking Methotrexate ...

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