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Review: could Methotrexate cause Diarrhoea?

We study 129,746 people who have side effects while taking Methotrexate from FDA and social media. Among them, 3,856 have Diarrhoea. Find out below who they are, when they have Diarrhoea and more.

Stay connected: join a mobile support group for people who take Methotrexate and have Diarrhoea >>>

Methotrexate

Methotrexate (latest outcomes from 131,079 users) has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis.

Diarrhoea

Diarrhoea (latest reports from 1,107,090 patients) has been reported by people with high blood pressure, pain, rheumatoid arthritis, osteoporosis, depression.

On Jul, 17, 2014: 129,740 people reported to have side effects when taking Methotrexate. Among them, 3,856 people (2.97%) have Diarrhoea. They amount to 0.35% of all the 1,096,364 people who have Diarrhoea on eHealthMe.

Trend of Diarrhoea in Methotrexate reports

Time on Methotrexate when people have Diarrhoea * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Diarrhoea48.78%20.45%5.24%5.07%13.11%4.90%2.45%

Gender of people who have Diarrhoea when taking Methotrexate * :

FemaleMale
Diarrhoea71.55%28.45%

Age of people who have Diarrhoea when taking Methotrexate * :

0-12-910-1920-2930-3940-4950-5960+
Diarrhoea0.93%5.55%7.64%4.09%7.87%13.08%24.22%36.62%

Severity of Diarrhoea when taking Methotrexate ** :

leastmoderateseveremost severe
Diarrhoea0.00%58.33%25.00%16.67%

How people recovered from Diarrhoea ** :

while on the drugafter off the drugnot yet
Diarrhoea0.00%14.29%85.71%

Top conditions involved for these people * :

  1. Rheumatoid arthritis (1,668 people, 43.26%)
  2. Pain (256 people, 6.64%)
  3. Prophylaxis (236 people, 6.12%)
  4. Osteoporosis (217 people, 5.63%)
  5. Hypertension (209 people, 5.42%)

Top co-used drugs for these people * :

  1. Folic acid (1,148 people, 29.77%)
  2. Prednisone (926 people, 24.01%)
  3. Humira (835 people, 21.65%)
  4. Enbrel (783 people, 20.31%)
  5. Remicade (456 people, 11.83%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Comments from related studies:

  • From this study (1 year ago):

  • Injected 4 doses of Methotrexate. Am now at 6 weeks after last methotrexate injection. Diarrhea and nausea are getting worse instead of better.

    Reply

  • From this study (2 years ago):

  • B.R.Bahl on Nov, 25, 2012:

    MY WIFE HAS BEEN USING fosavance 70 mg for the last 4 years without break.She feels fed up with the medicine,should she discontinue and use the one at monthly intervals.would you please reply which is the best medicine. Is there loss/damage if she discontinues.She feels no relief from the pain in the right side of her body.she takes pain killer medicine,doctor tell her to continue using till we are alive and forever.She feel difficulty to walk even upto few yards .She feel bodily and mentally weakness.will you pl tell her what she should do,continue to take or discontinue the medicine.

    Reply

    CC on Nov, 30, 2012:

    I saw the same symptoms on Mystery Diagnosis. It was the patient’s thyroid. Have your wife go to a thyroid specialist.

    Reply

  • From this study (3 years ago):

  • Mrs Susan Spence on Dec, 9, 2011:

    WITHOUT YOUR HELP I WOULD NEVER HAVE KNOWN WHY I STARTED SLEEP WALKING AND ASHAMED TO SAY WET THE BED. I HAVE PSORIASIS ARTHRITIS AND WAS STARTED ON PLAQUENIL WHILST ALREADY TAKING A HIGH DOSE OF AMITRIPTYLINE. DURING SLEEP WALKING I FELL OVER AND CRACKED MY HEAD SERIOUSLY. WITHIN 48 HOURS OF WITHDRAWING MYSELF OFF PLAQUENIL I WAS BACK TO NORMAL. THANKYOU SO MUCH. I AM PASSING THIS ON TO THE HEALTH PROFESSIONALS THAT NEED TO KNOW.

    Reply

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More reviews for: Methotrexate, Diarrhoea

On eHealthMe, Methotrexate (methotrexate sodium) is often used for rheumatoid arthritis. Find out below the conditions Methotrexate is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Methotrexate used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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