Could Methotrexate cause Diarrhoea - from FDA reports


Summary

Diarrhoea is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Humira, and have Rheumatoid arthritis . We study 209,150 people who have side effects while taking Methotrexate from FDA. Among them, 5,805 have Diarrhoea. Find out below who they are, when they have Diarrhoea and more.

What to expect?

If you take Methotrexate and have Diarrhoea, find out what symptoms you could have in 1 year or longer.

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Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 212,533 users)

Diarrhoea

Diarrhoea has been reported by people with high blood pressure, multiple sclerosis, rheumatoid arthritis, crohn's disease, pain (latest reports from 264,594 Diarrhoea patients).

On Jan, 17, 2017

209,150 people reported to have side effects when taking Methotrexate.
Among them, 5,805 people (2.78%) have Diarrhoea


Number of reports submitted per year:

Could Methotrexate cause Diarrhoea?

Time on Methotrexate when people have Diarrhoea *:

  • < 1 month: 43.97 %
  • 1 - 6 months: 18.73 %
  • 6 - 12 months: 7.65 %
  • 1 - 2 years: 7.49 %
  • 2 - 5 years: 11.56 %
  • 5 - 10 years: 7.49 %
  • 10+ years: 3.09 %

Gender of people who have Diarrhoea when taking Methotrexate *:

  • female: 72.76 %
  • male: 27.24 %

Age of people who have Diarrhoea when taking Methotrexate *:

  • 0-1: 1.27 %
  • 2-9: 4.45 %
  • 10-19: 6.35 %
  • 20-29: 4.15 %
  • 30-39: 7.03 %
  • 40-49: 14.42 %
  • 50-59: 25.86 %
  • 60+: 36.48 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (2,707 people, 46.63%)
  • Psoriatic Arthropathy (454 people, 7.82%)
  • High Blood Pressure (377 people, 6.49%)
  • Pain (354 people, 6.10%)
  • Crohn's Disease (319 people, 5.50%)

Top co-used drugs for these people *:

  • Humira (1,303 people, 22.45%)
  • Folic Acid (1,144 people, 19.71%)
  • Enbrel (1,047 people, 18.04%)
  • Prednisone (771 people, 13.28%)
  • Remicade (425 people, 7.32%)

Top other side effects for these people *:

  • Nausea (1,609 people, 27.72%)
  • Nausea And Vomiting (1,541 people, 26.55%)
  • Fever (953 people, 16.42%)
  • Abdominal Pain (874 people, 15.06%)
  • Fatigue (832 people, 14.33%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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