Review: could Methotrexate cause Headache?
Summary: Headache is found among people who take Methotrexate, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take medication Enbrel, and have Rheumatoid arthritis.
We study 129,897 people who have side effects while taking Methotrexate from FDA and social media. Among them, 3,827 have Headache. Find out below who they are, when they have Headache and more.
You are not alone: join a mobile support group for people who take Methotrexate and have Headache >>>
Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from 131,243 Methotrexate users)
Headache (pain in head) has been reported by people with multiple sclerosis, depression, high blood pressure, rheumatoid arthritis, osteoporosis. (latest reports from 202,378 Headache patients)
On Feb, 12, 2015: 129,882 people reported to have side effects when taking Methotrexate. Among them, 4,574 people (3.52%) have Headache.
Time on Methotrexate when people have Headache * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
Gender of people who have Headache when taking Methotrexate * :
Age of people who have Headache when taking Methotrexate * :
Severity of Headache when taking Methotrexate ** :
|least||moderate||severe||most severe |
How people recovered from Headache ** :
|while on the drug||after off the drug||not yet |
Top conditions involved for these people * :
- Rheumatoid arthritis (2,421 people, 52.93%)
- Pain (299 people, 6.54%)
- Psoriatic arthropathy (257 people, 5.62%)
- Hypertension (185 people, 4.04%)
- Psoriasis (159 people, 3.48%)
Top co-used drugs for these people * :
- Enbrel (1,576 people, 34.46%)
- Folic acid (1,497 people, 32.73%)
- Humira (1,115 people, 24.38%)
- Prednisone (951 people, 20.79%)
- Remicade (603 people, 13.18%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
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Can you answer these questions (Ask a question):
- I too have hashimoto's and hydrocephalus
I have been HYPOTHYROID since at least 18 years old, now 43, and last 2 years found out that I did test positive for Hashimotos and was told I have no thyroid left. When I was 26, I had visual disturbance and went to the ER. Was told by the neurologist that I had mild hydroencephaly, and may require a shunt. Due to lack of insurance, went years with no treatment or follow up. Now have numerous problems with Hashimotos/Hypothyroid and investigating the correlation between the Hydroencephaly and Hashimotos. Is this the only study of the two relations?
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Having psoriaticarthritis,fibromyalgia,psoriais,restless leg syndrome,roseacea and high blood pressure means complex health issues and a complex list of medication to go with it. Iam suffering extreme sweating,flushing and now a tickled cough. Now it could be due to going through the change (menopause) but that started a year ago and although I was getting the flushes and sweating,it was nothing like it is now! To me,it seems the excessive sweating started roughly a month after taking Humira. Having so many health issues I'm in tune with any changes and note and monitor them. I started Humira 10 months ago now. My Psoriasis has cleared completely so I'm really pleased. Usually,there's a trade off and you end up with something else! Could the issues I have be down to a single drug on the list,or a combination?
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Can these things be connected?
- Would the tinnitus abate with if i discontinue methotrexate?
I've just begun my 4th year of Methotrexate for Rheumatoid issue, but it also alleviated my psoriasis. I am hesitant to discontinue because the benefits are great. However, the tinnitus is becoming unbearable and almost maddening. I will more likely consider talking to my doctor about changing medications if 1. The tinnitus subsides with the discontinuance of Methotrexate and if 2. Other rheumatoid medication would not have the same issues with tinnitus. Just discovered the possible connection minutes ago and am eager and hopeful. Please help. Thank you. -Celeste
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Comments from related studies:
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I had the flu for two weeks it has been gone two weeks but I stayed fatigued with dry cough. I had my infusion of Simponi Aria 10 days ago. My Methotrexate injection is due tomorrow.
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All lesions necrosis
I live in chronic pain and fatigue
Lisa on Sep, 4, 2014:
Female 55 I have bechets. Diagnosed at 39. I take every medication on that list except I dropped methotrexate. I worse since I dropped it. And I have every symptom including ganglion cyst which needs to be surgically removed to the throat lesion. I can barely function. The only 5hing I dont have is the allergic cough. I did have mrsa phenomia once. Oh most recently plursey. I have been ivig dependent for 13 years.
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