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Review: could Methotrexate cause Headache?





Summary: Headache is found among people who take Methotrexate, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take medication Enbrel, and have Rheumatoid arthritis.

We study 129,858 people who have side effects while taking Methotrexate from FDA and social media. Among them, 4,573 have Headache. Find out below who they are, when they have Headache and more.

You are not alone: join a mobile support group for people who take Methotrexate and have Headache >>>

Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (view latest outcomes from 131,201 users)

Headache

Headache (pain in head) has been reported by people with multiple sclerosis, depression, high blood pressure, rheumatoid arthritis, osteoporosis.(latest reports from Headache 199,069 patients)

On Dec, 13, 2014: 129,841 people reported to have side effects when taking Methotrexate. Among them, 4,573 people (3.52%) have Headache.

Trend of Headache in Methotrexate reports

Time on Methotrexate when people have Headache * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Headache31.75%16.83%13.02%8.57%8.57%12.38%8.89%

Gender of people who have Headache when taking Methotrexate * :

FemaleMale
Headache77.72%22.28%

Age of people who have Headache when taking Methotrexate * :

0-12-910-1920-2930-3940-4950-5960+
Headache0.00%3.54%7.21%5.43%10.12%18.37%27.52%27.81%

Severity of Headache when taking Methotrexate ** :

leastmoderateseveremost severe
Headache12.50%56.25%25.00%6.25%

How people recovered from Headache ** :

while on the drugafter off the drugnot yet
Headache6.25%0.00%93.75%

Top conditions involved for these people * :

  1. Rheumatoid arthritis (2,420 people, 52.92%)
  2. Pain (299 people, 6.54%)
  3. Psoriatic arthropathy (257 people, 5.62%)
  4. Hypertension (185 people, 4.05%)
  5. Psoriasis (159 people, 3.48%)

Top co-used drugs for these people * :

  1. Enbrel (1,576 people, 34.46%)
  2. Folic acid (1,497 people, 32.74%)
  3. Humira (1,115 people, 24.38%)
  4. Prednisone (950 people, 20.77%)
  5. Remicade (603 people, 13.19%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Headache while taking Methotrexate?

You are not alone! Join a mobile support group:
- support group for people who take Methotrexate and have Headache
- support group for people who take Methotrexate
- support group for people who have Headache

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