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Review: could Methotrexate cause Headache?

Summary: Headache is found among people who take Methotrexate, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take medication Enbrel, and have Rheumatoid arthritis.

We study 129,908 people who have side effects while taking Methotrexate from FDA and social media. Among them, 4,574 have Headache. Find out below who they are, when they have Headache and more.

You are not alone: join a support group for people who take Methotrexate and have Headache >>>

 

Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from 131,250 Methotrexate users)

Headache

Headache (pain in head) has been reported by people with multiple sclerosis, depression, high blood pressure, rheumatoid arthritis, osteoporosis. (latest reports from 202,409 Headache patients)

On Mar, 15, 2015: 129,897 people reported to have side effects when taking Methotrexate. Among them, 4,574 people (3.52%) have Headache.

Trend of Headache in Methotrexate reports

Time on Methotrexate when people have Headache * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Headache31.65%16.77%12.97%8.54%8.54%12.66%8.86%

Gender of people who have Headache when taking Methotrexate * :

FemaleMale
Headache77.72%22.28%

Age of people who have Headache when taking Methotrexate * :

0-12-910-1920-2930-3940-4950-5960+
Headache0.00%3.54%7.21%5.42%10.12%18.37%27.52%27.83%

Severity of Headache when taking Methotrexate ** :

leastmoderateseveremost severe
Headache12.12%57.58%24.24%6.06%

How people recovered from Headache ** :

while on the drugafter off the drugnot yet
Headache5.88%0.00%94.12%

Top conditions involved for these people * :

  1. Rheumatoid arthritis (2,421 people, 52.93%)
  2. Pain (299 people, 6.54%)
  3. Psoriatic arthropathy (257 people, 5.62%)
  4. Hypertension (185 people, 4.04%)
  5. Psoriasis (159 people, 3.48%)

Top co-used drugs for these people * :

  1. Enbrel (1,576 people, 34.46%)
  2. Folic acid (1,497 people, 32.73%)
  3. Humira (1,115 people, 24.38%)
  4. Prednisone (951 people, 20.79%)
  5. Remicade (603 people, 13.18%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of methotrexate and headache on

Do you have Headache while taking Methotrexate?

 

 

 

You are not alone! Join a mobile support group on :
- support group for people who take Methotrexate and have Headache
- support group for people who take Methotrexate
- support group for people who have Headache

Drugs in real world that are associated with:

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Recent Methotrexate related drug comparison:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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