Review: could Methotrexate cause Headache?
Summary: Headache is found among people who take Methotrexate, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take medication Enbrel, and have Rheumatoid arthritis.
We study 129,858 people who have side effects while taking Methotrexate from FDA and social media. Among them, 4,573 have Headache. Find out below who they are, when they have Headache and more.
You are not alone: join a mobile support group for people who take Methotrexate and have Headache >>>
Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (view latest outcomes from 131,201 users)
Headache (pain in head) has been reported by people with multiple sclerosis, depression, high blood pressure, rheumatoid arthritis, osteoporosis.(latest reports from Headache 199,069 patients)
On Dec, 13, 2014: 129,841 people reported to have side effects when taking Methotrexate. Among them, 4,573 people (3.52%) have Headache.
Time on Methotrexate when people have Headache * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
Gender of people who have Headache when taking Methotrexate * :
Age of people who have Headache when taking Methotrexate * :
Severity of Headache when taking Methotrexate ** :
|least||moderate||severe||most severe |
How people recovered from Headache ** :
|while on the drug||after off the drug||not yet |
Top conditions involved for these people * :
- Rheumatoid arthritis (2,420 people, 52.92%)
- Pain (299 people, 6.54%)
- Psoriatic arthropathy (257 people, 5.62%)
- Hypertension (185 people, 4.05%)
- Psoriasis (159 people, 3.48%)
Top co-used drugs for these people * :
- Enbrel (1,576 people, 34.46%)
- Folic acid (1,497 people, 32.74%)
- Humira (1,115 people, 24.38%)
- Prednisone (950 people, 20.77%)
- Remicade (603 people, 13.19%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Do you have Headache while taking Methotrexate?
You are not alone! Join a mobile support group:
- support group for people who take Methotrexate and have Headache
- support group for people who take Methotrexate
- support group for people who have Headache
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- Hlab27 antigen and unexplained scratches caused by accutane
Guinea pig user of Accutane 1982. Experimental drug (told at that time) when a woman hits menopause we are not sure what will happen. I have hit early menopause 42 to be exact. Conjunctivitis, unexplained swelling in fingers, toes, kness, pseudogout (not normal according to my rheumatologist) unexplained scratches in same location, forearms, lower thigh (by knee) fingers. Scratches always are in a line with a break in the line. When a woman hits menopause hormones cease and when this happens the path that Accutane takes to cease sebaceous gland function, skin proliferation ceases. Therefore, my friends the HLA B27 (abnormal antigen targeted for skin proliferation does not know where to go so it randomly attacks whatever organ it chooses. Accutane if I remember correctly and I do have proof, permanently alters DNA. There is no other way orally ingesting a retinolic acid it could control skin, hormonal cesessation. I have only been diagnosed thus far with psoriatic arthritis with no other explanations for these other symptoms. I wonder why this is and I also wonder why dermatologists refuse to take a biopsy of my skin to rule out cell skin proliferation dysfunction. What will this damaging drug attack next. Do no be fooled by Dr.s who tell you that you took this drug so long ago how could this be. Well folks, it is because it has already changed your DNA to the HLAB27 antigen. My question also is, what was supposed to be where this abnormal DNA antigen is and how come this antigen only shows up at menopause. My disease (autoimmune) is progressive) and has already attacked nervous, muscle, skin, joints etc. Interesting
- What's the best home remedy for jaundice?
I started out thinking that I had pancreatitis, had all the symptoms, abdominal pain that went all the way thru to the back & inability to digest food (chronic indigestion). I read about keeping the bodys pH better balanced, bought pH test strips (urine) & found I was very acidic. I began eating more alkaline foods, alkalizing my water, and avoiding really acidic foods. Stopped taking my acid reducers because they actually KEPT me more acidic. I noticed that when my body's pH was up (alkaline) the pain was tolerable but when it began to drop (acid) the pain kicked up again. My doctors say they don't necessarily think it's pancreatitis because the ultrasound doesn't show inflammation & my blood test numbers are only slightly elevated. My liver enzymes are also slightly elevated. The doctors don't Seem very concerned. Today, for the first time in 2 months since this whole thing started I noticed I'm jaundiced. What the heck is this?
More questions for: Methotrexate, Headache
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I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, sulfasalazine, etc. My best results came with methotrexate after I got cellulitis in my knee (scratch it while kayaking in the summer, fiberglass boat). It dropped my sed rate from over 100 to 35 or so within a few months. I continued with MTX from 1977 to 2000 when my MD suggested Enbrel and stopping MTX. That was a VERY bad decision. Enbrel appeared to mask the disease for a few years. I had my left MCP replaced in 2004, my right heel debrided in 2010, and both my TMJs replaced in 2012. I strongly believe that if I had kept with the MTX it would have delayed those changes. Additionally, in 2011 I was in a bus crash returning from RAGBRAI. I got knocked out from three to six minutes. I had a nasty concussion that lasted 2+ years. Towards the end of the third year post accident I started exercising more aggressively. After doing several 40, 50, and 60 miles rides, I took a leisurely 50 mile ride around Boston at night. Two days later I had a spinal edema. So much for biking and other active sports! :-(
I have continued with MTX. Late 2013 my MD increased my MTX to .8/week. I had been taking .6/week. I stopped taking Enbrel and switched to Humira in early 2014. I took it for a few months before my doc and I realized it was not doing any better than Enbrel. I tried Humira for three months but it did not seem to work any better than Enbrel. In early June I stopped Humira and waited a few weeks before I started Otezla. I stopped Oterzla on 9/15/14 because it made me depressed and allowed my morning stiffness to get much worse.
I started prednisone again from the start of July. By mid-August I told my MD that I was screaming louder than I ever had; my dog was very startled. I stopped it gradually over the next two weeks. Meanwhile, the Otezla made me feel awful.
My MD is going to get me onto another injectable that I take monthly. I forget its name.
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I became ill several years ago.
It all started with a head cold that lasted a few months and left me with Tinnitus and chronic sinusitis.
After a nose operation and many visits to the doc and hospital, I am no closer to felling better or being cured.
My doc gave me Beconase Aq at first and this made me very unwell, causing me fatigue which would last for a few days. I'm still searching for help.
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Comments from related drug studies (Check your drugs):
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