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Review: could Methotrexate cause Hearing loss?

Summary: Hearing loss is found among people who take Methotrexate, especially for people who are female, 30-39 old, have been taking the drug for 1 - 6 months, also take medication Humira, and have Rheumatoid arthritis.

We study 129,882 people who have side effects while taking Methotrexate from FDA and social media. Among them, 235 have Hearing loss. Find out below who they are, when they have Hearing loss and more.

You are not alone: join a mobile support group for people who take Methotrexate and have Hearing loss >>>

 

 

 

 

Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from 131,224 Methotrexate users)

Hearing loss

Hearing loss has been reported by people with osteoporosis, high blood pressure, depression, rheumatoid arthritis, high blood cholesterol. (latest reports from 7,893 Hearing loss patients)

On Jan, 12, 2015: 129,858 people reported to have side effects when taking Methotrexate. Among them, 198 people (0.15%) have Hearing Loss.

Trend of Hearing loss in Methotrexate reports

Time on Methotrexate when people have Hearing loss * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Hearing loss7.14%42.86%7.14%14.29%28.57%0.00%0.00%

Gender of people who have Hearing loss when taking Methotrexate * :

FemaleMale
Hearing loss76.35%23.65%

Age of people who have Hearing loss when taking Methotrexate * :

0-12-910-1920-2930-3940-4950-5960+
Hearing loss0.49%6.31%3.40%7.28%25.24%17.96%25.24%14.08%

Severity of Hearing loss when taking Methotrexate ** :

leastmoderateseveremost severe
Hearing loss0.00%75.00%25.00%0.00%

How people recovered from Hearing loss ** :

while on the drugafter off the drugnot yet
Hearing loss0.00%50.00%50.00%

Top conditions involved for these people * :

  1. Rheumatoid arthritis (125 people, 63.13%)
  2. Arthritis (53 people, 26.77%)
  3. Pain (51 people, 25.76%)
  4. Cardiac disorder (47 people, 23.74%)
  5. Blood cholesterol increased (45 people, 22.73%)

Top co-used drugs for these people * :

  1. Humira (104 people, 52.53%)
  2. Folic acid (100 people, 50.51%)
  3. Prednisone (70 people, 35.35%)
  4. Aspirin (57 people, 28.79%)
  5. Nexium (55 people, 27.78%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Hearing Loss while taking Methotrexate?

You are not alone! Join a mobile support group:
- support group for people who take Methotrexate and have Hearing Loss
- support group for people who take Methotrexate
- support group for people who have Hearing Loss

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More questions for: Methotrexate, Hearing loss

You may be interested at these reviews (Write a review):

  • Humira: my experience
    I have had some form of arthritis probably since birth. My father and maternal grandfather had some form of arthritis. I began to realize pain in both ankles if I stood or walked too long.

    I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, sulfasalazine, etc. My best results came with methotrexate after I got cellulitis in my knee (scratch it while kayaking in the summer, fiberglass boat). It dropped my sed rate from over 100 to 35 or so within a few months. I continued with MTX from 1977 to 2000 when my MD suggested Enbrel and stopping MTX. That was a VERY bad decision. Enbrel appeared to mask the disease for a few years. I had my left MCP replaced in 2004, my right heel debrided in 2010, and both my TMJs replaced in 2012. I strongly believe that if I had kept with the MTX it would have delayed those changes. Additionally, in 2011 I was in a bus crash returning from RAGBRAI. I got knocked out from three to six minutes. I had a nasty concussion that lasted 2+ years. Towards the end of the third year post accident I started exercising more aggressively. After doing several 40, 50, and 60 miles rides, I took a leisurely 50 mile ride around Boston at night. Two days later I had a spinal edema. So much for biking and other active sports! :-(

    I have continued with MTX. Late 2013 my MD increased my MTX to .8/week. I had been taking .6/week. I stopped taking Enbrel and switched to Humira in early 2014. I took it for a few months before my doc and I realized it was not doing any better than Enbrel. I tried Humira for three months but it did not seem to work any better than Enbrel. In early June I stopped Humira and waited a few weeks before I started Otezla. I stopped Oterzla on 9/15/14 because it made me depressed and allowed my morning stiffness to get much worse.

    I started prednisone again from the start of July. By mid-August I told my MD that I was screaming louder than I ever had; my dog was very startled. I stopped it gradually over the next two weeks. Meanwhile, the Otezla made me feel awful.

    My MD is going to get me onto another injectable that I take monthly. I forget its name.
  • Psoratic arthritis and trigeminal neuralgia
    hi i suffer from psorisis and psoratic athritis i was just diagnosed with trigeminal neuralgia i was looking for the connection between the two and i see that there is one from your study
    the thing is all 13 people in the study said to have psoriatic arthropathy yet only one said to have psoratic arthritis yet to the best of my knowledge it is the same condition just a diffrent name which means all those studied have psoratic arthritis like me
    also i have not been taking those medicines in the study yet i have the same condition so if you take me into account could be the oly conecction between all of us is the psorisis and psoratic arthritis and not the medicine
  • Zetia causes deafness
    Took for two weeks and now have complete deafness. This was back in 2012.
  • Spiriva caused me to swell up like a hippo.
    My Doctor prescribed spiriva to help me breathe due to asthma/cold. I never smoked but my parents and friends were heavy smokers. I used the spiriva 3 times. Once a day for 3 days then I started swelling in my ankles and the swelling continued until my face, hands arms... basically I was so swollen I gained 29 pounds in two days. My doctor put me on lasix and potassium for several weeks. I quit using the spiriva when my other doctor asked if I was on any new meds. Spiriva was the only new medicine. When I stopped using it the swelling went away.
  • Isoniazid and deafness
    As a young girl I was put on Isoniazid, I didn't put 2 and 2 together but after taking the inh I started loosing my hearing to the point I'm completely deaf in my left ear. I have found a few people having report that they lost their hearing also. I'm just curious as to about how many people have had this problem.

More reviews for: Methotrexate, Hearing loss

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