Methotrexate and Hepatic cirrhosis - from FDA reports


Summary

Hepatic cirrhosis is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for 5 - 10 years, also take medication Humira, and have Rheumatoid arthritis. This review analyzes which people have Hepatic cirrhosis with Methotrexate. It is created by eHealthMe based on reports of 223,372 people who have side effects when taking Methotrexate from FDA, and is updated regularly.

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On Apr, 17, 2017

223,372 people reported to have side effects when taking Methotrexate.
Among them, 404 people (0.18%) have Hepatic Cirrhosis


Number of reports submitted per year:

Could Methotrexate cause Hepatic cirrhosis?

Time on Methotrexate when people have Hepatic Cirrhosis *:

  • < 1 month: 7.23 %
  • 1 - 6 months: 8.43 %
  • 6 - 12 months: 14.46 %
  • 1 - 2 years: 13.25 %
  • 2 - 5 years: 20.48 %
  • 5 - 10 years: 24.1 %
  • 10+ years: 12.05 %

Gender of people who have Hepatic Cirrhosis when taking Methotrexate *:

  • female: 57.88 %
  • male: 42.12 %

Age of people who have Hepatic Cirrhosis when taking Methotrexate *:

  • 0-1: 0.0 %
  • 2-9: 1.08 %
  • 10-19: 1.79 %
  • 20-29: 7.53 %
  • 30-39: 2.87 %
  • 40-49: 8.96 %
  • 50-59: 26.88 %
  • 60+: 50.9 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (193 people, 47.77%)
  • Psoriasis (52 people, 12.87%)
  • Psoriatic Arthropathy (44 people, 10.89%)
  • High Blood Pressure (27 people, 6.68%)
  • Pain (17 people, 4.21%)

Top co-used drugs for these people *:

  • Humira (126 people, 31.19%)
  • Enbrel (67 people, 16.58%)
  • Remicade (48 people, 11.88%)
  • Folic Acid (47 people, 11.63%)
  • Prednisolone (30 people, 7.43%)

Top other side effects for these people *:

  • Ascites (58 people, 14.36%)
  • Portal Hypertension (34 people, 8.42%)
  • Varices Oesophageal (33 people, 8.17%)
  • Thrombocytopenia (33 people, 8.17%)
  • Hepatic Steatosis (33 people, 8.17%)

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Hepatic cirrhosis when taking Methotrexate?

Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 226,881 users)

Hepatic Cirrhosis

Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue) has been reported by people with hepatitis c, high blood pressure, hiv infection, rheumatoid arthritis, diabetes (latest reports from 12,694 Hepatic cirrhosis patients).

Browse all side effects of Methotrexate

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Drugs that are associated with Hepatic cirrhosis

Hepatic cirrhosis

Could your condition cause Hepatic cirrhosis

Hepatic cirrhosis

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What would happen?

Forecast new side effects and undetected conditions when you take Methotrexate and have Hepatic cirrhosis.

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