Review: could Methotrexate cause Hepatic cirrhosis?
Summary: Hepatic cirrhosis is found among people who take Methotrexate, especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months, also take medication Humira, and have Rheumatoid arthritis.
We study 129,908 people who have side effects while taking Methotrexate from FDA and social media. Among them, 266 have Hepatic cirrhosis. Find out below who they are, when they have Hepatic cirrhosis and more.
You are not alone: join a support group for people who take Methotrexate and have Hepatic cirrhosis >>>
Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from 131,250 Methotrexate users)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue) has been reported by people with hepatitis c, hiv infection, high blood pressure, diabetes, rheumatoid arthritis. (latest reports from 8,925 Hepatic cirrhosis patients)
On Mar, 16, 2015: 129,897 people reported to have side effects when taking Methotrexate. Among them, 266 people (0.20%) have Hepatic Cirrhosis.
Time on Methotrexate when people have Hepatic cirrhosis * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Hepatic cirrhosis||11.11%||19.75%||20.99%||13.58%||17.28%||8.64%||8.64% |
Gender of people who have Hepatic cirrhosis when taking Methotrexate * :
|Hepatic cirrhosis||57.59%||42.41% |
Age of people who have Hepatic cirrhosis when taking Methotrexate * :
|Hepatic cirrhosis||0.00%||0.83%||2.07%||6.20%||1.24%||10.33%||34.71%||44.63% |
Severity of Hepatic cirrhosis when taking Methotrexate ** :
How people recovered from Hepatic cirrhosis ** :
Top conditions involved for these people * :
- Rheumatoid arthritis (126 people, 47.37%)
- Ankylosing spondylitis (28 people, 10.53%)
- Urticaria (26 people, 9.77%)
- Hypertension (23 people, 8.65%)
- Psoriatic arthropathy (19 people, 7.14%)
Top co-used drugs for these people * :
- Humira (91 people, 34.21%)
- Prednisolone (45 people, 16.92%)
- Folic acid (45 people, 16.92%)
- Prednisone (43 people, 16.17%)
- Remicade (41 people, 15.41%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Get connected: join our support group of methotrexate and hepatic cirrhosis on
Do you have Hepatic Cirrhosis while taking Methotrexate?
You are not alone! Join a mobile support group on :
- support group for people who take Methotrexate and have Hepatic Cirrhosis
- support group for people who take Methotrexate
- support group for people who have Hepatic Cirrhosis
Drugs in real world that are associated with:
Could your condition cause:
- A study of side effects of Methotrexate for a 40-year old woman with Rheumatoid Arthritis. The patient has Elevated Mood
- A study of side effects of Methotrexate for a 53-year old woman with Rheumatoid Arthritis. The patient has Hearing Loss, Ringing In The Ears (a ringing in the ears)
- A study of side effects of Methotrexate for a 71-year old man with RA. The patient has Itching - Burning Eyes, Muscle Weakness (a lack of muscle strength)
- A study of drug interactions between Folic Acid, Methotrexate, Enbrel for a 51-year old woman with Rheumatoid Arthritis. The patient has Nausea, Abdominal Pain
- A study of drug interactions between Metoprolol Succinate, Methotrexate Sodium Preservative Free, Plavix, Plaquenil, Humira, Folic Acid, Atorvastatin Calcium for a 59-year old woman with Coronary Artery Disease, Rheumatoid Arthritis, High Blood Cholesterol. The patient has Weight Gain
Recent Methotrexate related drug comparison:
NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.
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