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Review: could Methotrexate cause Hepatic cirrhosis?

We study 129,746 people who have side effects while taking Methotrexate from FDA and social media. Among them, 266 have Hepatic cirrhosis. Find out below who they are, when they have Hepatic cirrhosis and more.

Stay connected: join a mobile support group for people who take Methotrexate and have Hepatic cirrhosis >>>

Methotrexate

Methotrexate (latest outcomes from 131,070 users) has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis.

Hepatic cirrhosis

Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue) (latest reports from 42,845 patients) has been reported by people with hepatitis c, hiv infection, high blood pressure, diabetes, rheumatoid arthritis.

On Jul, 17, 2014: 129,740 people reported to have side effects when taking Methotrexate. Among them, 266 people (0.21%) have Hepatic Cirrhosis. They amount to 0.62% of all the 42,839 people who have Hepatic Cirrhosis on eHealthMe.

Trend of Hepatic cirrhosis in Methotrexate reports

Time on Methotrexate when people have Hepatic cirrhosis * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Hepatic cirrhosis11.11%19.75%20.99%13.58%17.28%8.64%8.64%

Gender of people who have Hepatic cirrhosis when taking Methotrexate * :

FemaleMale
Hepatic cirrhosis57.59%42.41%

Age of people who have Hepatic cirrhosis when taking Methotrexate * :

0-12-910-1920-2930-3940-4950-5960+
Hepatic cirrhosis0.00%0.83%2.07%6.20%1.24%10.33%34.71%44.63%

Severity of Hepatic cirrhosis when taking Methotrexate ** :

n/a

How people recovered from Hepatic cirrhosis ** :

n/a

Top conditions involved for these people * :

  1. Rheumatoid arthritis (126 people, 47.37%)
  2. Ankylosing spondylitis (28 people, 10.53%)
  3. Urticaria (26 people, 9.77%)
  4. Hypertension (23 people, 8.65%)
  5. Psoriatic arthropathy (19 people, 7.14%)

Top co-used drugs for these people * :

  1. Humira (91 people, 34.21%)
  2. Prednisolone (45 people, 16.92%)
  3. Folic acid (45 people, 16.92%)
  4. Prednisone (43 people, 16.17%)
  5. Remicade (41 people, 15.41%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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  • From this study (2 weeks ago):

  • I've been diagnosed with sero-negative rheumatoid arthritis. I have only tested minimally positive on the anti-CCP test and had a slightly high SED rate. My most recent tests showed some slight elevation in some RA marker tests, but nothing really significant. My rheumatologist is now doubting whether I have RA or some other pain syndrome going on.

    Reply

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On eHealthMe, Methotrexate (methotrexate sodium) is often used for rheumatoid arthritis. Find out below the conditions Methotrexate is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Methotrexate used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

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