Review: could Methotrexate cause Intraocular Pressure Increased?


Intraocular pressure increased is found among people who take Methotrexate, especially for people who are female, 50-59 old , have been taking the drug for < 1 month, also take medication Folic Acid, and have Rheumatoid arthritis . We study 128,587 people who have side effects while taking Methotrexate from FDA and social media. Among them, 94 have Intraocular pressure increased. Find out below who they are, when they have Intraocular pressure increased and more.

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Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 129,243 users)

Intraocular Pressure Increased

Intraocular pressure increased has been reported by people with breathing difficulty, hypotension, diplopia, tinnitus, eye swelling (latest reports from 5,707 Intraocular pressure increased patients).

On Jul, 27, 2016

128,587 people reported to have side effects when taking Methotrexate.
Among them, 94 people (0.07%) have Intraocular Pressure Increased

Number of reports submitted per year:

Could Methotrexate cause Intraocular pressure increased?

Time on Methotrexate when people have Intraocular Pressure Increased *:

  • < 1 month: 75 %
  • 1 - 6 months: 25 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Intraocular Pressure Increased when taking Methotrexate *:

  • female: 71.74 %
  • male: 28.26 %

Age of people who have Intraocular Pressure Increased when taking Methotrexate *:

  • 0-1: 0.0 %
  • 2-9: 26.67 %
  • 10-19: 9.33 %
  • 20-29: 0.0 %
  • 30-39: 2.67 %
  • 40-49: 8.0 %
  • 50-59: 33.33 %
  • 60+: 20.0 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (30 people)
  • Vitamin Supplementation (8 people)
  • Uveitis (8 people)
  • Psoriasis (8 people)
  • Hypertension (6 people)

Top co-used drugs for these people *:

  • Folic Acid (29 people)
  • Humira (19 people)
  • Prednisone (16 people)
  • Prednisolone (16 people)
  • Enbrel (10 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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