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Review: could Methotrexate cause Intraocular pressure increased?

We study 129,765 people who have side effects while taking Methotrexate from FDA and social media. Among them, 78 have Intraocular pressure increased. Find out below who they are, when they have Intraocular pressure increased and more.

Stay connected: join a mobile support group for people who take Methotrexate and have Intraocular pressure increased >>>

Methotrexate

Methotrexate (latest outcomes from 131,091 users) has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis.

Intraocular pressure increased

Intraocular pressure increased (latest reports from 24,864 patients) has been reported by people with glaucoma, high blood pressure, macular degeneration, high blood cholesterol, depression.

On Aug, 17, 2014: 129,757 people reported to have side effects when taking Methotrexate. Among them, 78 people (0.06%) have Intraocular Pressure Increased. They amount to 0.31% of all the 24,863 people who have Intraocular Pressure Increased on eHealthMe.

Trend of Intraocular pressure increased in Methotrexate reports

Time on Methotrexate when people have Intraocular pressure increased * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Intraocular pressure increased85.71%14.29%0.00%0.00%0.00%0.00%0.00%

Gender of people who have Intraocular pressure increased when taking Methotrexate * :

FemaleMale
Intraocular pressure increased73.79%26.21%

Age of people who have Intraocular pressure increased when taking Methotrexate * :

0-12-910-1920-2930-3940-4950-5960+
Intraocular pressure increased0.00%24.10%8.43%0.00%2.41%7.23%38.55%19.28%

Severity of Intraocular pressure increased when taking Methotrexate ** :

n/a

How people recovered from Intraocular pressure increased ** :

n/a

Top conditions involved for these people * :

  1. Rheumatoid arthritis (37 people, 47.44%)
  2. Acute lymphocytic leukaemia (15 people, 19.23%)
  3. Psoriasis (14 people, 17.95%)
  4. Vitamin supplementation (14 people, 17.95%)
  5. Uveitis (9 people, 11.54%)

Top co-used drugs for these people * :

  1. Folic acid (38 people, 48.72%)
  2. Prednisolone (29 people, 37.18%)
  3. Humira (27 people, 34.62%)
  4. Prednisone (21 people, 26.92%)
  5. Dexamethasone (20 people, 25.64%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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- group for people who take Methotrexate and have Intraocular Pressure Increased
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- group for people who have Intraocular Pressure Increased

Comments from related studies:

  • From this study (4 days ago):

  • I have been taking methotrexate 10 mg (one injection a week) since 2002. I was then under Metoject (Methotrexate) 10 mg and then 7.5 mg until February 2013 when I had mouth sores. I was told I had mouth cancer in April 2014 and has been operated mid May at the Pitie Salpetriere hospital in Paris.

    Reply

  • From this study (6 days ago):

  • I have exhausted all drug options for overactive bladder due to "resistance." Including Botox injections that had moderate results but only lasted almost two months. Also, every injection was painfully felt although I was prepped with a pain minimizing treatment. I am searching for help if any of my medication are causing the resistance.

    Reply

  • From this study (2 weeks ago):

  • I've been diagnosed with sero-negative rheumatoid arthritis. I have only tested minimally positive on the anti-CCP test and had a slightly high SED rate. My most recent tests showed some slight elevation in some RA marker tests, but nothing really significant. My rheumatologist is now doubting whether I have RA or some other pain syndrome going on.

    Reply

    IHateRA on Jul, 22, 2014:

    My first RA Dr. put me on Plaquenil, it seemed to work for six months, then stopped - I thought the dose would be adjusted but it wasn't, so I went to another RA Doc - C-RP wasn't too high, sero neg. Was put on methotrexate - I ended up with a mouth sore the NEXT day, then bumps started appearing on my face, like zits, but NOT zits. I didn't touch them, but they ulcerated, left me full of scars on face, legs, etc - I have been OFF methotrexate for 5 years AND still have the same problem along with a daily fever (100+) and severe sweating - I knew the bumps were a sign of being allergic to Methotrexate, I quit it right away, called Dr. to get in - they told me 3 months (I was an established patient). In terms of fever and sweating, the ONLY thing I have in common with some of these posts and drug lists is METHOTREXATE - I wouldn't allow a pet to take it. I seem to have more in common with a friend who as MS - but my reg. doc doesn't listen to that. I can't take bio. drugs (live in "fungal" region), so I take pain medicine - as little as possible, I guess the Methotrexate is STILL messing with my body. I have a very good acupuncturist - when I told him that my Doc. wasn't "sure" about RA, he poked me (lightly) with his finger in two places and ask which hurt more. He confirmed the RA as it travels on certain meridians in Chinese medicine. Had I picked a different spot for hurting more, then we would have to figure out what I really had. My joints are deteriorating but now I'm afraid of the drugs for RA, so I just put up with and manage the pain (which is extreme) with pain meds, cold therapy (I love my cryo-cuff), and acupuncture. I wish that the side effects of RA drugs weren't as bad as they are! Leaving Cymbalta, Lyrica, Plaquenil and Methotrexate (all at different times) OUT of my body made me realize that they did affect me - I was "foggy" and sluggish mentally but didn't really notice it until I quit them.

    Reply

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On eHealthMe, Methotrexate (methotrexate sodium) is often used for rheumatoid arthritis. Find out below the conditions Methotrexate is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

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