Could Methotrexate cause Itching - from FDA reports


Summary

Itching is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Enbrel, and have Rheumatoid arthritis . We study 197,039 people who have side effects while taking Methotrexate from FDA. Among them, 2,817 have Itching. Find out below who they are, when they have Itching and more.

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Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 212,501 users)

Itching

Itching has been reported by people with high blood cholesterol, rheumatoid arthritis (latest reports from 150,264 Itching patients).

On Dec, 02, 2016

197,039 people reported to have side effects when taking Methotrexate.
Among them, 2,817 people (1.43%) have Itching


Number of reports submitted per year:

Could Methotrexate cause Itching?

Time on Methotrexate when people have Itching *:

  • < 1 month: 41.03 %
  • 1 - 6 months: 15.38 %
  • 6 - 12 months: 8.97 %
  • 1 - 2 years: 10.9 %
  • 2 - 5 years: 14.1 %
  • 5 - 10 years: 7.69 %
  • 10+ years: 1.92 %

Gender of people who have Itching when taking Methotrexate *:

  • female: 79.96 %
  • male: 20.04 %

Age of people who have Itching when taking Methotrexate *:

  • 0-1: 0.05 %
  • 2-9: 1.42 %
  • 10-19: 3.71 %
  • 20-29: 3.94 %
  • 30-39: 7.89 %
  • 40-49: 17.01 %
  • 50-59: 29.16 %
  • 60+: 36.82 %

Severity of Itching **:

  • least: 10 %
  • moderate: 40 %
  • severe: 40 %
  • most severe: 10 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (1,553 people, 55.13%)
  • Psoriatic Arthropathy (202 people, 7.17%)
  • Psoriasis (195 people, 6.92%)
  • High Blood Pressure (194 people, 6.89%)
  • Pain (179 people, 6.35%)

Top co-used drugs for these people *:

  • Enbrel (776 people, 27.55%)
  • Humira (764 people, 27.12%)
  • Folic Acid (748 people, 26.55%)
  • Prednisone (388 people, 13.77%)
  • Remicade (300 people, 10.65%)

Top other side effects for these people *:

  • Rashes (923 people, 32.77%)
  • Joint Pain (358 people, 12.71%)
  • Pain (343 people, 12.18%)
  • Nausea (292 people, 10.37%)
  • Urticaria (283 people, 10.05%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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